ESPE Abstracts

Background: Diabetic Ketoacidosis (DKA) is a serious complication of type 1 diabetes mellitus (T1DM) that require prompt recognition, diagnosis and treatment. There is wide geographic variation in the frequency of DKA at onset of diabetes.Objective: To determine frequency of DKA in children and adolescents with newly diagnosed type 1 diabetes admitted to a tertiary care hospital in Turkey.Methods: A retrospective study was undertak...

Background: There is no specific guideline for management of children with type 1 diabetes just after diabetic ketoacidosis (DKA) treatment. There are different insulin dosage practices (from 0.8 to 2.0 U/kg per day) in different centres based on personal experiences.Objective and hypotheses: To assess daily subcutaneous insulin requirements and frequency of hypoglycaemic events (blood glucose < 50 mg/dl) just after DKA treatment of children with typ...

Background: Idiopathic intracranial hypertension (IIH) is a disorder of elevated intracranial pressure without any evidence of intracranial pathology or underlying systemic disease. Obesity was reported as a significant cause of IIH in childhood especially in adolescents.Objective and hypotheses: IIH is a disorder of elevated intracranial pressure without any evidence of intracranial pathology or underlying systemic disease. Obesity was reported as a sig...

Objective: The aim of this study was to investigate the effect of COVID-19 pandemic restrictions on the frequency of diabetic ketoacidosis (DKA) at the time of diagnosis in children with type 1 diabetes (T1D).Method: The medical records of children with T1D who were diagnosed between 16.03.2018 and 16.03.2022 in pediatric endocrinology clinics in Elazig province in Turkey were retrospectively reviewed for the presence of...

Background: Vitamin D Dependent Rickets Type IA(VDDR1a) is an autosomal recessive disorder characterized by defects in the biosynthesis of its active form 1,25 dihydroxyvitamin D due to the mutations in the CYP27B1 gene encoding for the enzyme 1α-hydroxylase.Objective and hypotheses: To evaluatethe clinical characteristics, molecular genetics aetiology and long-term outcome of a large nationwide cohort of VDDR-Ia f...

Aim: Hypophosphatemic rickets (HR) is a rare renal phosphate wasting disorder commonly related to X-linked form, caused by PHEX mutations and it treatment and follow-up is challenging due to imperfect treatment options. Here we presented nationwide data on HR with initial and follow-up data on the patients presented to the pediatric endocrinology clinics before the age of 18 years.Results: From 24 centers, 158 patients (93 male/65 female) were i...

Objective: The aim of this study was to evaluate demographic characteristics; clinical, laboratory, imaging features; and response to treatment of boys who were followed up and treated with the diagnosis of central precocious puberty (CPP) in Turkiye.Materials and Methods: The study was planned as a multicenter, retrospective study. Cases with a diagnosis of CPP, whose follow-up data were available were included. Patient...