hrp0097rfc9.5 | Diabetes and insulin 2 | ESPE2023
, Raile Klemens
, Galler Angela
, Wiegand Susanna
Introduction: Childhood obesity shows increasing numbers worldwide and presents as a global health issue due to multiple metabolic comorbidities. About 1 % of adolescents with obesity develop type 2 diabetes (T2D), however little is known about the genetic and pathophysiological background in young age. Genome-wide association studies in adults revealed genes with increased diabetes risk, most of them regulating insulin secretion. The objective of this study w...