hrp0097p1-445 | Fat, Metabolism and Obesity | ESPE2023

Impact of early-life overweight/obesity trajectory on insulin resistance at age 8: a prospective cohort study

Jin Lee Hye , Jeong Lee Yun , Lim Youn-Hee , Hong Yun-Chul , Ho Shin Choong , Ah Lee Young

Objective: To investigate whether the early-life overweight/obesity trajectory from ages 2, 4, to 8 affects insulin resistance (IR) in 8-year-old prepubertal children.Methods: From the Environment and Development of Children (EDC) cohort, 262 prepubertal children (147 boys and 115 girls) who visited Seoul National University Children’s Hospital for anthropometric measurements at ages 2, 4 and 8 were included. At ag...