hrp0095p2-301 | Late Breaking | ESPE2022

Analysis of Factors Affecting Bone Mineral Density in Children and Adolescents with systemic lupus erythematosus

Jin Park Su , Bae Ahn Moon , Suh Byung-Kyu

Background: Children and adolescents with chronic disease are at risk of developing bone fragility. In particular, low bone mineral density (BMD) is increasingly recognized in pediatric patients with glucocorticoid treated rheumatic disease. The purpose of this study was to evaluate the clinical characteristics of children and adolescents with systemic lupus erythematosus (SLE), and to analyze the factors associated with a lower BMD in these patients.<p cl...

hrp0097p1-421 | Bone, Growth Plate and Mineral Metabolism | ESPE2023

Bisphosphonate, sirolimus, atenolol treatment in a 4-year old child diagnosed with Gorham-Stout disease

Jin Park Su , Yeun Sim Soo , Suh Byung-Kyu , Bae Ahn Moon

Gorham-Stout disease(GSD), also known as vanishing bone disease is an extremely rare skeletal disorder characterized by idiopathic intraosseous proliferation of lymphatic vascular structures resulting in progressive resorption of bone. Herein, we report a case of a 4-year-old girl with GSD treated with the combination treatment with bisphosphonate, sirolimus, and atenolol. A 4-year-old girl presented with prolonged back pain for 2 weeks. The thoracolumbar spine radiography rev...

hrp0097p1-32 | Diabetes and Insulin | ESPE2023

Continuous Glucose Monitoring: A possible aid to detect hypoglycemia event during insulin challenge tests

Yeun Sim Soo , Jin Park Su , Bae Ahn Moon , Suh Byung-Kyu

Combined pituitary function test is a dynamic function test used to evaluate the anterior pituitary gland in patients suspected with hypopituitarism. The test comprises insulin challenge test where intravenous insulin injection in order to induce symptomatic hypoglycemia (serum blood glucose <40mg/dL). Insufficient increase in growth hormone and cortisol after the stimulation confirms the diagnosis of growth hormone deficiency and/or adrenal function insufficiency. However,...

hrp0095lb3 | Late Breaking | ESPE2022

High Glycated Hemoglobin instead of High Body Mass Index Might Increase the Urine N-acetyl-β-D-glucosaminidase Concentration in Children and Adolescents with Diabetes Mellitus

Jin Park Su , Bae Ahn Moon , Suh Jin-Soon , Soon Cho Kyoung , Ho Jung Min , Suh Byung-Kyu

Children with diabetes, and particularly those with obesity, have poor glycemic control. They are thus at higher risk of early microvascular complications. Renal tubulointerstitial markers are integral to evaluating diabetic nephropathy. Various biomarkers have been proposed, but their role in the obese pediatric population is uncertain. We investigated renal injury markers in children with diabetes, according to obesity, and determined their role as early predictors of diabet...