hrp0089p3-p143 | Fat, Metabolism and Obesity P3 | ESPE2018

Acanthosis Nigricans in Obese Children and Adolescents in relation to Severity of Obesity and Insulin Resistance

Hee Park Kyung , Jung Lim Hyun , Myoung Kim Yoon

Acnathosis nigricans (AN) is known to be common dermatologic manifestation in obese children and adolescents. The aim of this study is to examine the association of AN and insulin resistance in obese children and adolescents. One hundred seventy-nine obese subjects aged 6-17 years who participated in the intervention study, Childhood and Adolescents Obesity via Activity and Nutrition (ICAAN) study, were enrolled in 2017-2017. AN was diagnosed by physician. Anthropomet...

hrp0097p2-92 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

A case of pituitary stalk interruption syndrome of normal height with chronic fatigue and delayed puberty

Choi Yunha , Kyung Jung Mo , Yoo Han-Wook

Pituitary stalk interruption syndrome (PSIS) is a rare congenital pituitary anatomical defect with endocrine abnormalities. The triad of this syndrome comprises thin or interrupted pituitary stalk, absent or ectopic posterior lobe, and hypoplastic or aplastic anterior pituitary lobe. We diagnosed a 16-year-old female patient with combined pituitary hormone deficiency (CPHD) due to PSIS. The patient complained of chronic fatigue and was Tanner stage 1 with no signs of puberty. ...

hrp0095p1-480 | Fat, Metabolism and Obesity | ESPE2022

Clinical symptom and sequence variations in patients with sitosterolemia

Kyung Jung Mo , Rhie Seonkyeong , Kim Mira , Hun Seo Go , Choi Man-ho , Yoo Eun-Gyong

Backgrounds: Sitosterolemia is an inborn error of sterol metabolism caused by pathogenic variation of ABCG5 or ABCG8. It is characterized by increased plant sterol levels, xanthomas, and accelerated atherosclerosis; however, it is likely to be underdiagnosed in the clinical field. This study aims to describe the genetic variance of clinically confirmed patients with sitosterolemia and analyze the clinical spectrum according to genetic variance.<p class="ab...

hrp0097p1-394 | Thyroid | ESPE2023

Assessment of five domains of neurodevelopment and growth in congenital hypothyroidism: Serial 6-year follow-up study of 408 patients

Kyung Jung Mo , Kyo Ha Eun , Ryung Cha Hey , Yong Han Man

Background: There is a link between congenital hypothyroidism (CH) and neurodevelopmental abnormalities, but no longitudinal studies have yet identified reliable quantifiable measures.Purpose: To evaluate associations between CH and abnormalities in neurodevelopment and growth, and identify the timing of these abnormalities and the best time for intervention.Methods: Data from the ...

hrp0097p1-130 | Growth and Syndromes | ESPE2023

The differences of clinical characteristics and effect of growth hormone treatment according to karyotype classification in Turner syndrome patients

soon Kim Hae , Eun Choi Jung , Won Huh Jung , So Min-Kyung , Jung Park Mi , Yu Jeesuk

Objectives: Short stature is the main characteristics for Turner syndrome (TS) patients, and growth hormone (GH) therapy has been used as an essential treatment for developing final adult height. However, there are only a few studies on the difference responsiveness to GH therapy according to the karyotype of Turner syndrome in Korea. The aim of this study was to analyze the effect of different types of TS karyotype abnormality on the response of GH therapy.</...

hrp0084p3-756 | Diabetes | ESPE2015

Factors Related to Progression to Macroalbuminuria in Type 1 Diabetic Children with Microalbuminuria

Choi Keun Hee , Kim Hwa Young , Jung Hae Woon , Lee Gyung Min , Jung Kyung A , Kim So Youn , Lee Young Ah , Chung Hye Rim , Shin Choong Ho , Yang Sei Won

Background: Microalbuminuria is usually the earliest sign of diabetic nephropathy. However, it does not always progress to macroalbuminuria,and may regress to normoalbuminuria. Mean HbA1c and HbA1c variability was known to be independent risk factors for microalbuminuria in children with type 1 diabetes.Objective and hypotheses: We hypothesised that both mean and variability of HbA1c could affect the progression to macroalbuminuria in children with type ...

hrp0097p1-120 | Growth and Syndromes | ESPE2023

Personalized behavioral change technique intervention with TUITEK® patient support program to support caregivers of children treated with growth hormone in Korea

Wook Chae Hyun , Sil Oh Eun , van Dommelen Paula , Jang Kyungmi , Kyung Jung Mo , Hyang Cho Ja , Suh Junghwan , Eun Moon Jung , Koledova Ekaterina , Yang Yoo-Jin , Yoo Eun-Gyong

Background: Growth hormone (GH) treatment requires long-term self-management and optimized recombinant-human growth hormone (r-hGH) prescription. Patient support programs (PSPs) are vital in educating, providing personalised support to caregivers and enhancing patient care to achieve optimal growth outcomes. Nurse-led PSP calls using behavior change techniques (BCTs) and motivational interviewing principles have demonstrated a meaningful behavior change across...