hrp0089p3-p143 | Fat, Metabolism and Obesity P3 | ESPE2018

Acanthosis Nigricans in Obese Children and Adolescents in relation to Severity of Obesity and Insulin Resistance

Hee Park Kyung , Jung Lim Hyun , Myoung Kim Yoon

Acnathosis nigricans (AN) is known to be common dermatologic manifestation in obese children and adolescents. The aim of this study is to examine the association of AN and insulin resistance in obese children and adolescents. One hundred seventy-nine obese subjects aged 6-17 years who participated in the intervention study, Childhood and Adolescents Obesity via Activity and Nutrition (ICAAN) study, were enrolled in 2017-2017. AN was diagnosed by physician. Anthropomet...

hrp0095p1-480 | Fat, Metabolism and Obesity | ESPE2022

Clinical symptom and sequence variations in patients with sitosterolemia

Kyung Jung Mo , Rhie Seonkyeong , Kim Mira , Hun Seo Go , Choi Man-ho , Yoo Eun-Gyong

Backgrounds: Sitosterolemia is an inborn error of sterol metabolism caused by pathogenic variation of ABCG5 or ABCG8. It is characterized by increased plant sterol levels, xanthomas, and accelerated atherosclerosis; however, it is likely to be underdiagnosed in the clinical field. This study aims to describe the genetic variance of clinically confirmed patients with sitosterolemia and analyze the clinical spectrum according to genetic variance.<p class="ab...

hrp0084p3-756 | Diabetes | ESPE2015

Factors Related to Progression to Macroalbuminuria in Type 1 Diabetic Children with Microalbuminuria

Choi Keun Hee , Kim Hwa Young , Jung Hae Woon , Lee Gyung Min , Jung Kyung A , Kim So Youn , Lee Young Ah , Chung Hye Rim , Shin Choong Ho , Yang Sei Won

Background: Microalbuminuria is usually the earliest sign of diabetic nephropathy. However, it does not always progress to macroalbuminuria,and may regress to normoalbuminuria. Mean HbA1c and HbA1c variability was known to be independent risk factors for microalbuminuria in children with type 1 diabetes.Objective and hypotheses: We hypothesised that both mean and variability of HbA1c could affect the progression to macroalbuminuria in children with type ...