ESPE Abstracts

Background: Carriers of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21-OHD) demonstrate increased secretion of cortisol precursors following ACTH stimulation, suggestive of impaired cortisol production, and compensatory increases in hypothalamic CRH secretion. Both cortisol and CRH have behavioural effects, and hypothalamic CRH hypersecretion has been associated with chronic states of anxiety and depression.Objective and hypoth...

Introduction: Childhood obesity is one of the most challenging contemporary public health problems. Children and adolescents with obesity experience multiple psychosocial difficulties, such as low self-esteem, depression, anxiety, and behavioral problems. Psychosocial problems noted in youngsters with excess adiposity persist for a long time. The aim of our study was to assess mental health symptoms in overweight and obese children and adolescents before and a...

Background: Accumulating evidence suggests that decreased 25-hydroxyvitamin [25(OH)D] concentrations are associated with components of the metabolic syndrome.Objective: The aim of our study was to investigate the effect of vitamin D supplementation on metabolic syndrome parameters in obese children and adolescents.Patients and methods: Two hundred thirty two (n=232) obese children and adolescents aged [mean ±S....

Introduction: Childhood obesity has reached epidemic proportions in contemporary societies with multiple comorbidities. Social stigma, low self-esteem, depression, anxiety, and behavioral problems are noted in youth with excess adiposity, and may persist for a long time. The aim of our study was to assess the alterations in cardiometabolic risk factors and mental health in children and adolescents with excess adiposity following the implementation of a multidi...