hrp0095p1-59 | Diabetes and Insulin | ESPE2022

Type 1 diabetes glycated haemoglobin outcomes did not differ by insulin regimen in two large Cambodian tertiary hospitals

May Ng Sze , IV Malene , Yay Chantana , Chhun Khun Leang , Manet Ban , Martin Tyla , Lek Ngee

Introduction: Action 4 Diabetes (A4D) is a UK non-profit organisation which has been providing free insulin and self-monitoring blood glucose test kits for children and young people (CYP) with type 1 diabetes (T1D) in Cambodia’s 2 large tertiary hospitals-Kantha Bopha II Hospital based in Phnom Penh (KB2H) and Jayavarman VII Hospital based in Siem Reap (J7H), since July 2018 and January 2020, respectively.Objective:</strong...

hrp0089p2-p117 | Diabetes &amp; Insulin P2 | ESPE2018

Prevalence of and Risk Factors for Nonadherence to Insulin Among Paediatric Type 1 Diabetes Patients in Singapore

Chua Brandon , Stephanie Jamie , Lim XIn Yan , Poh Kar Men , Cheen McVin , Lim Soo Ting , Lek Ngee

Introduction: Nonadherence to insulin therapy is a significant problem worldwide, which is associated with poor health outcomes among patients with type 1 diabetes (T1D). It is important to identify the risk factors related to nonadherence to target those at higher risk of diabetic complications. In Singapore, there is a knowledge gap in understanding the risk factors for insulin nonadherence in paediatric patients with T1D.Objectives: To assess the prev...

hrp0084p2-243 | Diabetes | ESPE2015

Dyslipidaemia in Children with Diabetes

Lim Pei Kwee , Vasanwala Rashida , Cheng Tuck Seng , Lek Ngee , Hui Yuen Ching Angela , Lim Soo Ting , Yap Fabian

Background: Data on prevalence and phenotypic distribution of dyslipidaemia in children with type 1 diabetes (T1D) is scarce. Studies have shown that lipid abnormality tracks from childhood to adulthood and contributes to atherosclerotic process, therefore initial assessment and follow-up is essential.Aims: To study the prevalence and phenotypic distribution of dyslipidaemia in children with T1D and compare with type 2 diabetes (T2D).<p class="abstex...

hrp0095rfc8.4 | Diabetes and Insulin | ESPE2022

Developing a regional Southeast Asia diabetes healthcare professional network and webinars programme initiative during the pandemic

Sze May Ng , Lek Ngee , Sahakitrungruang Ngee , Pheng Chan Siew P , Yong Lai Mee , Yazid Jalaludin Muhammad , Thao Bui Muhammad , Nyi Nyi Soe , Ficheroulle Anne-Charlotte , Toomey Charles

Background: In 2020, the average glycaemic index of Type 1 diabetes (T1D) in Southeast Asia (SEA) countries were reported to be at around 83mmol/mol. In many low-middle-income countries (LMICs) in SEA, insufficient infrastructure, lack of universal health coverage and professional knowledge are factors that affect T1D outcomes that adversely affect mortality and morbidity. Action4diabetes (A4D) currently provides comprehensive partnership programmes with defin...

hrp0097p1-59 | Fat, Metabolism and Obesity | ESPE2023

Diagnostic value of soluble LEPR levels in the serum of patients with disease-causing biallelic LEPR variants

Zorn Stefanie , Tews Daniel , von Schnurbein Julia , Flehmig Bertram , Pridzun Lutz , Wabitsch Martin , Malene IV , Chantana Yay , Khun Leang Chhun , Ban Manet , Tyla Martin , Ngee Lek

Introduction: The soluble leptin receptor (sLR) is the main binding protein of leptin in the serum. It reflects the amount of membrane-bound leptin receptors (LEPR) as the sLR is produced by proteolytic cleavage of the extracellular domain of membrane-bound LEPR. Low sLR but high leptin levels were measured in patients with severe obesity. In patients with monogenic obesity caused by biallelic LEPR variants, sLR levels were found to be either undetect...

hrp0095p1-58 | Diabetes and Insulin | ESPE2022

Developing a digital Southeast Asia Type 1 diabetes healthcare educational platform in local languages during the pandemic

May Ng Sze , IV Malene , Khue Nguyen Thy , Le Khuong , Xian Lucas Lim Yang , Lek Ngee , Anuar Zaini Azriyanti , Seal Samantha , Yun Tange Steffen , Charlotte Ficheroulle Anne , Toomey Charles

Introduction: Action4Diabetes (A4D) is a non-profit UK organisation formed in 2016 that is making sustainable and scalable progress to provide quality Type 1 diabetes (T1D) healthcare in Southeast Asia (SEA). A4D provides comprehensive partnership programmes through a Memorandum of Understanding (MOU) signed with the governments in SEA that guarantees ongoing supplies of free insulin, blood glucose testing, HbA1c tests and hospital emergency funds in low-middl...