hrp0097p1-461 | Fat, Metabolism and Obesity | ESPE2023

Study on the correlation of metabolic syndrome with sex hormone binding protein and testosterone in obese boys

Yang Yu , Liang Yiwei

Objective: To explore the correlation of sex hormone-binding globulin (SHBG) and Total Testosterone (TT) with the development of Metabolic syndrome (MetS) in obese boys. To explore the relationship between components of MetS and TT levels in boys.Methods: A total of 439 boys aged 6-18 years old from April 2020 to February 2023, include boys who visited the Department of Endocrinology, Genetics and Metabolism in Jiangxi P...

hrp0098p2-130 | Fat, Metabolism and Obesity | ESPE2024

Genetic etiology and clinical phenotype of childhood obesity based on whole exon sequencing technology

Yang Yu , Huang Hui , Liang Yiwei , Yang Li , Xie Liling , Zhang Dongguang

Objective: This study investigated the genetic etiology and clinical phenotype of non-syndromic childhood and adolescent obesity.Methods: A total of 392 non-syndromic obese children aged 7-14 years old who were hospitalized in Department of Endocrinology. Whole exon sequencing was used to screen the potential genetic causes and analyze CNV and 79 reported obesity candidate genes.Results:</s...