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hrp0095p1-487 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2022

Early-Life Exposure to Phthalates in A Population of Infants from The North of Italy: Characterization and Time Trends

Lucaccioni Laura , Righi Elena , Trevisani Viola , Passini Erica , Palandri Lucia , Bruzzi Patrizia , Predieri Barbara , Iughetti Lorenzo

Background: Phthalates are ubiquitous environmental contaminants and endocrine-disrupting chemicals (EDCs). Nowadays, they are considered reproductive toxicants and in-utero exposure is well documented, although evidence of early life exposure is scarce, and needs to be described. Aim of this study is to assess phthalate exposure and its changes over the first months of life in a cohort of healthy full term infants and their mothers from a restricted area of t...

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hrp0095p1-349 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Use of Urinary Gonadotropins for The Evaluation of the Minipubertal Profile in Term Newborns and Infants Within The First Six Months of Age

Lucaccioni Laura , Trevisani Viola , Passini Erica , Palandri Lucia , Bruzzi Patrizia , Predieri Barbara , Righi Elena , Iughetti Lorenzo

Background: The activation of the hypothalamus-pituitary-gonadal (HPG) axis during the first months both in males(M) and females(F) is named as minipuberty. Urinary gonadotropins (uGn) represent an unexpensive and non-invasive method of assessing pubertal development and they have recently been used also for studying minipuberty.Aims of the study are: 1) to describe the urinary hormonal pattern (uLH, uFSH, testosterone – uT, oestra...

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hrp0097p1-479 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2023

Early-life exposure to phthalates and minipuberty: is there any relationship?

Lucaccioni Laura , Palandri Lucia , Trevisani Viola , Righi Beatrice , Calandra Bonaura Filippo , Predieri Barbara , Righi Elena , Iughetti Lorenzo

Background: Nowadays, the role of minipuberty in influencing pubertal development is well documented. Phthalates are ubiquitous environmental contaminants and endocrine-disrupting chemicals (EDCs) with reproductive toxic effect. Aim of this study is to assess phthalate exposure within the first months of life in a cohort of healthy term infants and their mothers and the possible relationship with minipuberty.Methods: Sin...

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hrp0098fc9.6 | Sex Endocrinology and Gonads | ESPE2024

The Gender Identity Questionnaire for Children: a useful tool for gender identity detection in early life

Trevisani Viola , Lucaccioni Laura , Palandri Lucia , De Pasquale Lisa , Insalaco Anna , Bruzzi Patrizia , Predieri Barbara , Righi Elena , Iughetti Lorenzo

Background: Gender identity (GI) is the unified and persistent self-perception on the male-female spectrum, and its acquisition is a multifactorial process maybe influenced also by minipuberty. GI develops in early childhood and is consolidated around 3-4 years. Several tests assess GI as the Gender Identity Questionnaire for Children (GIQC). GIQC is intended for parents and aims to assess GI in both clinical and non-clinical populations. Aim of the research i...

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hrp0098p1-193 | Sex Endocrinology and Gonads 2 | ESPE2024

Under the Lens: A Study of Childhood Gender Identity Through the Toy Preference Test and its relation to minipuberty

Lucaccioni Laura , Trevisani Viola , Errigo Denian , Palandri Lucia , De Pasquale Lisa , Bruzzi Patrizia , Predieri Barbara , Righi Elena , Iughetti Lorenzo

Background: Gender role behaviour refers to a set of behaviours that differ for boys and girls, although its source and development remain controversial. Gender differences in the choice of toys and activities are observed as early as 12 months. Ad hoc tests, such as the Toy Preference Test (TPT), have been developed to highlight gender differences in paediatric populations. The aim of our study was to investigate play behaviour, to determine which toys are mo...