hrp0086s6.2 | Prevention of childhood obesity | ESPE2016

Early Childhood Life Style Intervention and Obesity Outcome

Marcus Claude

Background: Treatment of childhood and adolescent obesity is rarely effective if “cure” i.e., BMI below the obesity range, is used as the definition of success. However, results of obesity treatment is much more effective if treatment is initiated in 6–7 years old children. It is therefore urgent to develop interventions for young children, both preventive and obesity treatment efforts. Results from such interventions as well as preliminary results from ongoing ...

hrp0084p3-918 | GH & IGF | ESPE2015

Are Short Children with Low GH Secretion Metabolically Different from Children of Normal Height?

Tidblad Anders , Ekstrom Klas , Ritzen Martin , Marcus Claude

Background: Severe GH deficiency (GHD) leads to several metabolic effects in the body ranging from abnormal body composition to biochemical disturbances such as high insulin sensitivity. However, less is known regarding these parameters in children with a milder deficiency in GH secretion.Objective and hypotheses: To analyse if short children with a relatively low GH secretion differ metabolically from healthy children of normal height.<p class="abst...

hrp0092p2-162 | GH and IGFs | ESPE2019

Metabolic Effects of Growth Hormone Treatment in Short Prepubertal Children: A Double-Blinded Randomized Clinical Trial

Tidblad Anders , Gustafsson Jan , Marcus Claude , Ritzén Martin , Ekström Klas

Objective: Growth hormone (GH) is a central hormone for regulating linear growth during childhood and also highly involved in metabolism of lipids, carbohydrates and protein. However, few studies report on how treatment with GH during childhood influences metabolic parameters. Our aim was to investigate metabolic effects of different doses of GH in short children with GH peak levels in the low normal range.Design: Thirty...

hrp0086p1-p216 | Diabetes P1 | ESPE2016

Thyroid and Islet Autoantibodies Predict Autoimmune Thyroid Disease Already at Diagnosis of Type 1 Diabetes

Jonsdottir Berglind , Larsson Christer , Carlsson Annelie , Forsander Gun , Anders Ivarsson Sten , Lernmark AEke , Ludvigsson Johnny , Marcus Claude , Samuelsson Ulf , Ortqvist Eva , Elding Larsson Helena

Background: Screening for autoimmune thyroid disease in children and adolescents with type 1 diabetes lacks consensus. Optimal screening methods should benefit the patients and reduce costs to healthcare.Objective and hypotheses: To, at diagnosis of type 1 diabetes, determine the predictive value of thyroid autoantibodies, thyroid function, islet autoantibodies, and HLA-DQ for autoimmune thyroid disease.Method: At diagnosis of type...