hrp0086p2-p327 | Diabetes P2 | ESPE2016

Benefits of Switching Insulin from Twice Daily to Multiple Daily Injections on Glycaemic Control in Children with Type 1 Diabetes Mellitus in Sri Lanka at the Lady Ridgeway Hospital, Sri Lanka

Atapattu Navoda , Vithanage Vasundara , De Silva Shamya

Introduction: Intensive insulin therapy with multiple daily injections (MDI) gives better glycaemic control than conventional biphasic insulin regimen in children with type 1 Diabetes mellitus. Though MDI regimen is widely practiced in other countries, this is not so in Sri Lanka.Objective: Effect on glycaemic control and BMI of children with TIDM after the change of insulin regimen to MDI from twice daily insulin regime. Methodology</st...

hrp0086p2-p435 | Gonads &amp; DSD P2 | ESPE2016

An Infant with 49XXXXY Syndrome: A Case Report from Sri Lanka

Atapattu Navoda , Liyanage Chaminda , Naotunna Chamidri

Introduction: 49XXXXY syndrome is the rarest X chromosome aneuploidy with an approximate incidence of 1: 85 000–100 000 male births. The classic triad of symptoms include mental retardation, hypogonadism and radioulnar synostosis along with congenital heart diseases; Patent Ductus Arteriosus being the commonest defect reported, Distinct facial features, skeletal defects, cerebral and renal defects. To the best of our knowledge this is the first reported case of 49XXXXY sy...

hrp0084p3-898 | Fat | ESPE2015

A Case of Rapid Onset Obesity, Hypoventilation, Hypothalamic Dysregulation and Neuroendocrine Tumours-ROHHADNET Syndrome

Atapattu Navoda , Dissanayaka Lalitha , Arulmoli S

Background: Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHADNET) is a rare disorder which presents in early childhood.Case presentation: Four years old girl was referred to endocrinology unit with a history of excessive weight gain. Parents noticed a rapid weight gain from 3 years of age with increase food seeking behaviour and daytime somnolence. Her weight was >95th centile and her height was o...

hrp0095p1-294 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2022

Foetal and Neonatal outcome of pregnant women with Thyroid Disorders

Gunasekara Buddhi , Wijeyaratne Chandrika , Atapattu Navoda , Lucas Nishani , Weliange Shreenika

Introduction: Thyroid disorders are the second commonest endocrine dysfunctions encounter in pregnancy after Diabetes. These include overt hypothyroidism, overt hyperthyroidism, subclinical hypothyroidism and subclinical hyperthyroidism. Pregnancy has profound impact on the thyroid gland and thyroid functions (TF). Failure to adapt to these physiological changes result in abnormal TF and cause adverse foetal and neonatal outcomes like miscarriages, placental a...

hrp0092p3-304 | Late Breaking Abstracts | ESPE2019

Congenital Craniopharyngioma - A Rare Case of Congenital Hypopituitarism

Suntharesan Jananie , Atapattu Navoda , Prematilake Dilusha , Hashim Raihana , Gunasekara Buddhi

Introduction: Hypopituitarism leads to one or more pituitary hormones deficiency. Hypopituitarism can be congenital or acquired. The incidence of congenital hypopituitarism is between 1 in 4000 and 1in 10 000 live births. Children with congenital hypopituitarism may present with hypoglycemia, hyponatremia, shock, micro phallus in males, and later present with growth failure. It can be due to congenital or acquired causes. Adamantinomatous type craniopharingiom...

hrp0092p3-321 | Late Breaking Abstracts | ESPE2019

Hydrometrocolpos Due to Congenital Adrenal Hyperplasia – A Rare Cause of Bladder Outflow Tract Obstruction in a Female Child

Suntharesan Jananie , Atapattu Navoda , Gunasekara Buddhi , De silva Dimarsha

Introduction: Hydrometrocolpos (HMC) develops in a female child as a result of a vaginal outflow tract obstruction and accumulation of secretions. HMC can have associated with other malformations or associated syndromes. Imperforated hymen, vaginal atresia, persistent urogenital sinus, and cloacal malformation, are the common causes for HMC. Congenital adrenal hyperplasia causing androgen exposure during the fetal life leads to varying degree of ambiguous geni...

hrp0089p2-p037 | Bone, Growth Plate &amp; Mineral Metabolism P2 | ESPE2018

Vitamin D Deficient (Nutritional) Rickets Presenting in Infancy

Prematilake Dilusha , Hashim Raihana , Kollurage Udeni , Atapattu Navoda

Background: Nutritional rickets is a disorder of defective chondrocyte differentiation and mineralization of the growth plate and osteoid due to vitamin D deficiency with or without low calcium intake in growing children. Maternal Vitamin D deficiency and exclusive breastfeeding without supplementation are the most frequent causes of rickets in the infancy. Vitamin D deficiency is still a problem in Sri Lanka in spite of sun shine throughout the year. We present a case series ...

hrp0084p3-627 | Adrenals | ESPE2015

Familial Glucocorticoid Deficiency – A Case Report

Atapattu Navoda , Mohomad Sureka , Rathnasiri Shammi , Wijesuriya Asoka Padmakanthi

Background: Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disorder associated with isolated glucocorticoid deficiency. Melanocortin−2 receptor (MC2R), account for approximately 25% of FGD cases.Case report: 3 year old girl presented with recurrent hypoglycaemic episodes from day 2 of life. She was a product of consanguineous family born with a birth weight of 2.3 kg. At birth she was found to be dark in complexion from birt...

hrp0094p2-482 | Thyroid | ESPE2021

Iodine status and autoimmune thyroiditis in children; a case-control study in Sri Lanka

Hashim Raihana , Mahesh Buddika , Atapattu Navoda , de Silva Shamya

Conclusions: Iodine nutrition status in children in both groups was optimal, based on urinary iodine concentration. Furthermore, there was no significant association between iodine intake and autoimmune thyroiditis....

hrp0097p1-141 | Multisystem Endocrine Disorders | ESPE2023

Bilateral adrenalectomy for Cushings syndrome in Infantile McCune Albright Syndrome(MAS)-A Case Report

Jayasundara Imalka , Atapattu Navoda , Siriwardhane Dinendra , Naotunna Chamidri , Hoole Thabitha

McCune Albright Syndrome is a rare disease characterized by classic triad of polyostotic fibrous dysplasia, café-au-lait spots and endocrine dysfunction and out of them cushings syndrome is a fatal manifestation which might need bilateral adrenalectomy. We report a 6 months old baby who presented to Paediatric Endocrinology Unit due to elevated alkaline phosphatase levels while investigating for failure to thrive, hypotonia and global developmental delay. This child was...