hrp0089ss1.3 | Special Symposia: Nutrition and Growth | ESPE2018

Interaction between Nutrition, the Endocrine System and the Growth Plate

Phillip Moshe

Children’s linear growth is a complex process determined by genetic and environmental factors. It is well known that nutrition influences linear growth, but the precise mechanisms by which nutrition interact with height gain was never fully elucidated. In the present lecture, the way by which nutrition affects linear growth will be discussed. Specifically, we will discuss the effect of nutrition on the GH- IGF-1 axis and its local effect on the chondrocytes of the epiphys...

hrp0089wg4.6 | ESPE Diabetes Technology and Therapeutics Working Group | ESPE2018

Updates on the Developments of Decision Support Systems for the Treatment of Diabetes

Phillip Moshe

With the increased number of patients with diabetes on one hand and the shortage of professional teams of health care providers (HCP) worldwide on the other hand, new ways of providing medical care to patients with diabetes are needed. Decision Support Systems (DSS) and emerging tools are developed in order to help HCP during patients’ office visits and to help patients navigate their own metabolic control between office visits. Recently, tools of DSS have been tested in ...

hrp0086wg5.6 | ESPE Diabetes Technology and Therapeutics Working Group | ESPE2016

Prescribing Software for the Treatment of Diabetes

Phillip Moshe

Management of Type1 diabetes is a challenge for both patients and health-care providers. The majority of patients worldwide are not reaching the desired glycemic control. Barriers to good control include risk of hypoglycemia, glucose monitoring limitations, technologies of insulin administration, scarceness of diabetes experts their limited time required in order to give the appropriate level of personalized treatment and supervision during patients’ visits. Other reasons...

hrp0082wg2.1 | Global paediatric Endocrinology and Diabetes | ESPE2014

Technological Horizon for the Treatment of Diabetes

Phillip Moshe

The daily treatment of pediatric patients with diabetes is challenging for patients, parents and medical teams. This is probably the reason why most patients all over the world do not meet the targets of glucose control defined by world organizations like ISPAD, EASD and the ADA as the safe zone for preventing complications, extending life expectancy and improving quality of life. New emerging technologies are in the pipeline of both academic centers and industry that promise ...

hrp0084wg2.3 | Diabetes Technology and Therapeutics Thursday, 1 October | ESPE2015

Are Genetic Tests Necessary before Starting the Treatment of a Patient with Neonatal Diabetes? CON

Phillip Moshe

Neonatal diabetes is defined by hyperglycemia either isolated or as a part of a syndrome, diagnosed within the first 6 months of life. This is a monogenic form of diabetes resulting from mutations in a number of different genes encoding proteins that play a key role in the normal function of the pancreatic β-cell. To date, over 20 genes have been identified in about 60–75% of cases. A significant breakthrough was the recognition that a large portion of patients can b...

hrp0092p2-115 | Fat, Metabolism and Obesity | ESPE2019

The Prevalence of Severe Obesity and Related Comorbidities has Increased During the Last Decade Among Children and Adolescents Referred for Evaluation at the Obesity Clinic

Avnieli Yael , Phillip Moshe , Shalitin Shlomit

Background/Aims: Childhood obesity has increased markedly during the past decades.The aim of the study was to examine the changes in trends of severe obesity and related comorbidities among children and adolescents referred for evaluation at the obesity clinic in a tertiary care center in Israel.Methods: The study included patients aged 2-18 years referred for evaluation due to obesity (BMI > 9...

hrp0084p2-435 | Gonads | ESPE2015

Clinical Criteria Remain Paramount for the Diagnosis of Polycystic Ovary Syndrome in the Adolescent Age Group

de Vries Liat , Weinberg Adi , Phillip Moshe

Background: Adolescent polycystic ovary syndrome (PCOS) may be difficult to distinguish from pubertal changes and diagnosis remains a challenge.Objective and hypotheses: To investigate the value of different biochemical parameters for the diagnosis of PCOS and also to assess the prevalence of non-classical congenital adrenal hyperplasia (NCCAH) among adolescent girls referred for clinical symptoms suggesting PCOS.Method: Retrospect...

hrp0097p1-335 | Multisystem Endocrine Disorders | ESPE2023

High yield of genetic testing in various endocrine disorders

Shefer Averbuch Noa , Orenstein Naama , Phillip Moshe

Background: A specialized endo-genetic service was established in our clinic in January 2018. The service is multi-disciplinary and includes not only endocrinologists but also other physicians from different fields (e.g urology, orthopedics, imaging), nursing staff, psychologists, social workers, dieticians, genetic laboratories and bioinformaticians. The service is now run by a board-certified physician in both pediatric endocrinology and medical genetics.</p...

hrp0095p1-329 | Growth and Syndromes | ESPE2022

Associations between Eating Patterns of Adolescents and Their Height and Weight, A Comparison Between Genders

Zur Maya , Fisch-Shvalb Naama , Phillip Moshe , Yackobovitch-Gavan Michal

Rationale: Adequate nutrition is essential for normal growth in childhood and adolescence. The high growth rate during adolescence demands high amounts of energy and various nutrients. During puberty, unlike infancy and early childhood, boys and girls of the same age have gender-specific nutritional needs. Our aim was to examine the associations between the dietary intake of male and female adolescents and their anthropometric measures.<...

hrp0095p2-138 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2022

Hypoglycemia in children: Clinical experience of a tertiary care center

Gil Margolis Merav , Lilos Pearl , Phillip Moshe , de Vries Liat

Introduction: Hypoglycemia is a significant cause of morbidity in children, yet is challenging to diagnose and treat due to its heterogeneity.Aim: To describe the diagnoses and clinical characteristics of children with hypoglycemia referred to a tertiary pediatric center.Methods: This retrospective study included 155 children (86 males, aged 0-18 years) diagnosed with hypoglycemia ...