ESPE Abstracts

Background: Central precocious puberty (CPP) and early puberty (EP) are characterized by premature breast development. Girls with CPP and EP who experience rapid pubertal progression are treated with gonadotropin-releasing hormone analog (GnRHa) to halt pubertal advancement and optimize height potential. However, studies on factors impacting near-final height (NFH) for CPP and EP in Asian girls remain scarce. We aim ed to explore the factors associated with pr...

Background: The incidence rate (IR) of childhood diabetes is increasing globally. These upward trends were also found in Thailand. However, newly diagnosed childhood diabetes incidences are not updated, especially in Northern Thailand. There are possibilities that COVID-19 pandemic affects the development of acute diabetes after infection and the severity of the first clinical presentation of childhood diabetes. However, data are also conflicting regarding the...

Background: Hyperthyroidism is a common condition in general pediatric practice. Several adult studies show hyperthyroidism affects health-related quality of life (HRQoL). However, information regarding HRQoL in the pediatric population is limited.Objectives: To evaluate HRQoL and psychosocial functioning of patients diagnosed with childhood primary hyperthyroidism compared with healthy controls and to identify the possi...

Background: Hypophosphatasia (HPP) is a rare inherited disease of bone metabolism caused by inactivating mutations in the ALPL gene encoding tissue non-specific alkaline phosphatase (TNSAP). Infantile HPP is characterized by early onset abnormal skeletal mineralization with hypercalcemia and low alkaline phosphatase (ALP). It has been rarely reported from Thailand, resulting in limited disease awareness. We reported an infantile HPP Thai patient who p...