hrp0095fc1.4 | Thyroid | ESPE2022

Children at cardio-metabolic risk raise their circulating concentrations of TSH and free T3

Carreras-Badosa Gemma , Mas-Parés Berta , Gómez-Vilarrubla Ariadna , Puerto-Carranza Elsa , Martinez-Calcerrada Jose-María , Riera-Pérez Elena , de Zegher Francis , Ibañez Lourdes , Bassols Judit , López-Bermejo Abel

Introduction: Thyroid hormones regulate body composition and metabolism, and are among the key drivers of body growth and maturation. In children, associations of cardio-metabolic measures with the circulating prohormone thyroxine (T4) have been extensively studied, but not with active triiodothyronine (T3). In apparently healthy children, we studied whether circulating free T3 (fT3) [and its ratio with free T4 (fT3/fT4)] associates with cardio-metabolic measu...

hrp0097rfc8.3 | Fat, metabolism and obesity 2 | ESPE2023

Higher levels of serum α-Klotho are longitudinally associated with less visceral fat accumulation in apparently healthy girls experiencing weight gain

Puerto-Carranza Elsa , Mas-Parés Berta , Gómez-Vilarrubla Ariadna , Díaz-Roldán Ferran , Riera-Pérez Elena , de Zegher Francis , Ibañez Lourdes , Bassols Judit , Carreras-Badosa Gemma , López-Bermejo Abel

Introduction: Klotho is an anti-aging protein that reduces adiposity and increases caloric expenditure, among others. Although associations between secreted α-Klotho levels and obesity have been described, its relationship with central obesity and visceral fat accumulation during childhood is poorly understood. Our objective was to study the longitudinal associations between serum α-Klotho concentrations and obesity parameters in apparently healthy...