ESPE Abstracts

Sick euthyroid syndrome (SES) is the most common endocrine disorder in critically ill patients. It has been shown that the decrease in T4 levels correlates with disease severity and prognosis. Whether SES is a compensatory response to the disease course or needs to be treated is not known yet. To our knowledge, there are only a few studies oncritically ill infants and children investigating the correlation between thyroid function and disease severity as well as its outcome. T...

Background: Obesity is one of health problems worldwide. Acanthosis nigricans has been considered as a symptom of hyperinsulinemia in children.Objective and hypotheses: We designed this study to evaluate and compare clinical and laboratory findings in Iranian obese children with and without acanthosis nigricans.Material: Seventy-one obese children enrolled. Fasting blood sugar, total cholesterol, triglycerides, alanine aminotransfe...

Background: Vitamin D deficiency is now a critical issue due to its high prevalence and side effects.Objective and hypotheses:: We assessed the serum vitamin D status of obese and non-obese children and comparing their therapeutic response to identical oral vitamin D consumption in Iran.Method: This study was performed in children aged 2–14 years at Children Medical Center of Tehran in Iran. At first, the serum 25-hydroxy vita...

Objective: β-thalassemia major is an autosomal recessive hemoglobinopathy that needs to blood transfusion for the survival of patients with β-thalassemia. Iron overload as a side effect of transfusion causes some endocrine deficiency in these patients. The injectable iron chelators as an only treatment in the past lead to painful among patients. At present, use of oral iron chelator and increase in patients’ compliance has been successful....