hrp0092p1-44 | Fat, Metabolism and Obesity | ESPE2019

Metabolic Complications After Paediatric Liver Transplantation: A 10-year Longitudinal Study in a South-East Asian Population

Beng Hui Ng Nicholas , Yijuan Lim Yvonne , Wei Li Ho Cindy , Anjian Sng Andrew , Aw Marion , Seng Lee Yung , Yin Loke Kah

Background: Improved patient and graft survival post-liver transplantation has led to a parallel increase in metabolic syndrome (MS) reported in multiple centres. We aimed to study the prevalence and risk factors of metabolic complications in our paediatric liver transplant (LT) cohort.Methods: This was a retrospective review of the LT database from 1995-2018. We studied the incidence of overweight, obesity (WHO BMI crit...

hrp0097p1-427 | Diabetes and Insulin | ESPE2023

Quality Improvement Initiative to Improve Influenza Vaccination Uptake Rates in Paediatric Patients with Diabetes Mellitus

Shan Carey Lim Yun , Yin Loke Kah , Seng Lee Yung , Andrew Sng Anjian , Su Annette , Yang Xiuji , Li Cindy Ho Wei , Yvonne Lim Yijuan , Hui Nicholas Ng Beng

Introduction: The annual incidence of severe influenza infections reaches 5 million cases globally. Patients with diabetes mellitus (DM) are known to suffer more severe influenza infections, with increased mortality. Despite vaccination being recommended as standard of care, vaccination uptake rates have remained low for our DM patients. We undertook a quality improvement (QI) initiative to improve influenza vaccination uptake rates in our paediatric DM clinic...

hrp0097p1-151 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Clinical profile of children with central precocious puberty in a single tertiary centre

Yen Wee Chun , Beng Hui Ng Nicholas , Wei Li Ho Cindy , Anjian Sng Andrew , Leiqiu Tay Vanerry , Seng Lee Yung , Yin Loke Kah , Yijuan Lim Yvonne

Introduction: Our study aimed to describe the clinical profile of children with central precocious puberty (CPP) presenting to a single tertiary centre, and to determine the factors that would lead patients and families to pursue treatment with gonadotrophin releasing hormone (GnRH) agonist as well as the predictors of a more favourable final adult height in this cohort.Methods: We conducted a retrospective medical chart...

hrp0089p1-p128 | Fat, Metabolism and Obesity P1 | ESPE2018

Rate of Accumulation of Abdominal Fat is Associated with Fasting Glucose Levels in Early Childhood

Anand Sadananthan Suresh , Thway Tint Mya , Michael Navin , Wei Pang Wei , Ling Loy See , Soh Shu-E , Shek Lynette , Yap Fabian , Hian Tan Kok , Kramer Michael , Eriksson Johan , Godfrey Keith , Gluckman Peter , Seng Chong Yap , Karnani Neerja , Seng Lee Yung , Fortier Marielle , Sendhil Velan S

Objectives: Abdominal fat has been strongly linked to increased cardiometabolic risk and impaired glucose regulation in adults. Owing to the lack of detailed body composition phenotyping in most previous child cohort studies, the temporal links between abdominal fat accumulation and impaired glucose regulation have not been well established. In this study, we evaluated the associations of abdominal fat assessed by MRI at early infancy (≤21 days after birth) and at 4.5 ye...