ESPE Abstracts

Introduction: Anogenital distance (AGD) is a useful marker of prenatal androgen exposure and a tool for assessment of differences of sex development. Normative data on AGD ranges for local references should be established as standards for comparison in clinical practice, but there is a paucity of data among newborns in Thailand.Aim: To provide the sex-specific ranges for AGD in Thai full-term newborns.<p class="abste...

Background: Subjects with impaired glucose tolerance (IGT) are at risk for type 2 diabetes mellitus (T2DM) and cardiovascular disease. The predictors of IGT in obese youth are not well described.Objective and hypotheses: We aim to evaluate insulin dynamics and biochemical markers for predicting IGT in Thai obese youth.Method: We studied 115 obese Thai children who underwent an oral glucose tolerance test (OGTT). Plasma glucose and ...

Background: Kisspeptin and Delta-like 1 homolog (DLK1) are neuropeptides that regulate pubertal timing by activating and inhibiting the hypothalamic-pituitary-gonadal axis; consequently, measuring these biomarkers could potentially distinguish central precocious puberty (CPP) from premature thelarche (PT) girls and monitor CPP treatment.Objectives: To compare baseline serum kisspeptin and DLK1 levels in girls with CPP at...