hrp0098p3-53 | Diabetes and Insulin | ESPE2024

Diabetic Neuropathic Cachexia and Mauriac Syndrome: A Rare Complication of Poorly Controlled Diabetes Mellitus

Djermane Adel , Fafa Abdennader , Ouarezki Yasmina , Ghedjati Asma , Kermi Lynda , Atek Laziz , Arous Radjaa , Semar Yasmine , Aggoune Samira , Maouche Hachemi

Background: Diabetic neuropathic cachexia is a rare syndrome of acute neuropathic pain and profound weight loss. Mauriac syndrome has rarely been reported in children and adolescents with a poorly controlled diabetes mellitus type 1. Common presenting features include short stature, growth retardation, moon facies, protuberant abdomen, and proximal muscle wasting. We report the first case of the association of Mauriac Syndrome and Diabetic neuropathic cachexia...

hrp0097p2-253 | Late Breaking | ESPE2023

Challenges and Outcomes of Using Insulin Analogues in Children with Diabetes in Low- and Middle-Income Countries.

Marzouk Asma , Laajili Mariem , Bouaziz Asma

Introduction: The selection of insulin therapy for children with type 1 diabetes (T1DM) poses a challenge, particularly in low- and middle-income countries. This study aimed to assess the utilization of insulin analogues in diabetic children and identify factors associated with achieving glycemic goals.Methods: In a retrospective study involving 80 children with T1DM, the impact of transitioning from human insulin to ins...

hrp0095p2-235 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Precocious puberty revealing a McCune Albright syndrome: About a case

Aoui Asma , Bessahraoui Mimouna

Introduction: McCune Albright syndrome (MAS) is classically defined by the clinical triad: fibrous dysplasia of bone, café-au-lait skin pigmentation and endocrinopathies :The most frequent is precocious puberty. Linked to a somatic mutation of the α subunit of the Gs protein, this syndrome leads to a constitutive activation of adenylate cyclase, to the excessive production of AMPcCase presentation: Here we r...

hrp0092p3-93 | Diabetes and Insulin | ESPE2019

Severe and Inaugural Diabetic Ketoacidosis in Children: Experience of a Pediatric Tunisian Department

guedria asma , Hadrich Zouhour

Introduction: Ketoacidosis is often indicative of diabetes in children in our Tunisian context. It can be severe and life-threatening, with mortality in the order of 1 to 2%.Methods: We report the results of a retrospective study over a period of 2 years (from 1/01/2017 to 31/12/2018) on all cases of inaugural ketoacidosis of type 1 diabetes mellitus in children, collected at the pediatric department of Mohamed Tlatl...

hrp0084p3-1177 | Thyroid | ESPE2015

The Correlation between TSH Levels and BMI Percentiles in Hypothyroid Children Who are Chemically Euthyroid on Levothyroxine Treatment

Shaoba Asma , Minutti Carla

Background: Prior research has shown a correlation between TSH levels and BMI in euthyroid subjects. Whether this relation can be applied to hypothyroid chemically euthyroid children has yet to be determined.Objective and hypotheses: To determine if there is a correlation between TSH levels and BMI percentiles in hypothyroid children who are chemically euthyroid on levothyroxine.Method: Retrospective chart review of patients from R...

hrp0094p2-102 | Diabetes and insulin | ESPE2021

Unmet need in technology for diabetes management in the Middle East, Africa and South East Asia

Alsaffar Hussain , Deeb Asma ,

Introduction: Diabetes is a global disease with approximately 425 millions of people affected throughout the world. The treatment cost for diabetes constitutes a significant economic burden and is estimated to increase in areas of Africa, South East Asia and the middle east in parallel to the increase to the disease incidence. These regions contribute differently in the global market revenue for the use of continuous glucose monitoring (CGM) and insulin pump t...

hrp0097p2-209 | Bone, Growth Plate and Mineral Metabolism | ESPE2023

Diagnostic and Management Challenges in X linked hypophosphatemic rickets:-A case series

Chaturvedi Deepti , Deeb Asma

Introduction: X Linked hypoposphatemic rickets (XLH) is a rare genetic disorder characterized by variable clinical features. It is often misdiagnosed with other types of rickets. A novel effective treatment is currently available. We report four cases of XLH who presented to our centre over a period of five years and describe their clinical presentation, diagnostic, treatment challenge and outcome.CASE 1 -The child presented with short s...

hrp0097p1-444 | Diabetes and Insulin | ESPE2023

From human insulin to insulin analogues: what impact on the BMI of children with type 1 diabetes?

Marzouk Asma , Laajili Mariem , Zouari Noura , Bouguila Jihene , Bouaziz ASma

Introduction:Despite the widely proven value of insulin analogs in the treatment of children with type 1 diabetes (T1D), pediatric studies of Increased weight gain in T1D are complicated by the age-dependency and gender-dependency of BMI, and also by a trend towards obesity in the general population.Objective: to assess the impact of switching from Humain Insulin (HI) to insulin analogues on the BMI of children with T1D....

hrp0098p3-343 | Late Breaking | ESPE2024

Primary amenorrhea in a 16-year-old girl

Fadel Asma , Bensallah Meriem , Dahlouk Djazia

Amenorrhea constitutes one of the primary reasons for consultation in reproductive medicine. Amenorrhea in adolescents can be either primary or secondary.Clinical Observation: She is a 16-year-old girl, born of a second-degree consanguineous marriage, the eldest of 2living siblings, She presents with primary amenorrhea. A aunt, aged 40, also presents with the same unexplored issue. The illness history dates back a year following primary ...

hrp0095p1-430 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

Importance of early detection of familial hypomagnesemia in preventing neurological handicap

Marzouk Asma , Tej Amel , Dworniczak Bernd , Donaldson Malcolm

Background: Hereditary hypomagnesemia with secondary hypocalcemia (HSH) is a are autosomal recessive disorder which presents in early infancy with generalized convulsions, or other symptoms related to increased neuromuscular excitability. Several mutations in the TRPM6 gene have been described. Early diagnosis is an effective means of preventing the inevitable neurocognitive sequelae which occur in the absence of appropriate treatment.<s...