hrp0098p1-275 | Pituitary, Neuroendocrinology and Puberty 4 | ESPE2024

Endocrine Deficiency after Photon and Proton Radiotherapy for Medulloblastoma in Hokkaido University Hospital, Japan.

Kaneko Naoya , Hishimura Nozomi , Morikawa Syuntaro , Terashita Yukayo , Hirabayashi Shinsuke , Cho Yuko , Hashimoto Takayuki , Yamaguchi Shigeru , Manabe Atsushi

Background: Medulloblastoma accounts for about 10% of pediatric brain tumor, and about 60 to 100 cases occur in Japan per year. After tumor removal, chemotherapy and radiation therapy including craniospinal irradiation (CSI) are performed. Since the irradiation range of CSI includes hypothalamus, pituitary gland, thyroid, ovaries, and spine, it is known that endocrine deficiency and growth disorders are frequent as late effects. In this study, we aim to highli...

hrp0089p3-p396 | Thyroid P3 | ESPE2018

Myastenia Gravis in a Girl with Hashimoto Thyroiditis

Gucev Zoran , Alili Laerta , Laban Nevenka , Tasic Velibor

Objective: To describe an association of Hashimoto’s thyroiditis and myasthenia gravis in a 16 years old girl.Patient Report and Methods: A 18-year old girl with persistent hypothyroidism secondary to Hashimoto’s thyroiditis and a family history of Hashimoto’s thyroiditis (grandmother), diagnosed in 2005 and confirmed by elevation of thyroid stimulating hormone (TSH), low levels of T3, T4 and fT4 levels. The US of the thyroid gland reveale...

hrp0086p1-p887 | Thyroid P1 | ESPE2016

EEG Alterations are Common in Hashimoto’s Thyroiditis

Boettcher Claudia , Brosig Burkhard , Windhaus Henriette , Kamrath Clemens , Wudy Stefan A. , Hahn Andreas

Background: Steroid responsive encephalopathy with autoimmune thyroiditis (SREAT) is a clinically and electrographically heterogeneous steroid-responsive encephalopathy associated with thyroid autoantibodies.Objective and hypotheses: To investigate, whether children and adolescents with Hashimoto’s Thyroiditis (HT) lacking acute clinical manifestation of SREAT show electroencephalogram (EEG) alterations, and to compare EEGs of HT patients with those...

hrp0082p1-d2-248 | Thyroid (1) | ESPE2014

Vitamin D in Adolescents with Hashimoto’s Thyroiditis

Gumeniuk Olga

Background: The results of several studies suggest that vitamin D could possibly decrease the risk of autoimmune diseases.Objective: To evaluate the efficiency of the vitamin D in adolescents with Hashimoto’s thyroiditis (HT).Methods: The study included 32 adolescents (aged 12–17 years, mean age was 14.4±1.3 years) with HT (normal range TSH, fT3, fT4 and elevated antibodies). HT was diagnosed on...

hrp0086p1-p930 | Thyroid P1 | ESPE2016

Seasonality of Month of Birth in Children and Adolescents with Hashimoto Thyroiditis

Kyrgios Ioannis , Giza Styliani , Kotanidou Eleni , Maggana Ioanna , Galli-Tsinopoulou Assimina

Background: A number of studies have previously described seasonality of birth in children with type 1 diabetes, thus suggesting that the autoimmune process may begin during fetal development. However, there is a lack of data regarding autoimmune thyroid disease in childhood.Objective and hypotheses: The aim of this study was to analyse the seasonal birth month pattern in young patients with Hashimoto thyroiditis and compare it with that of youth healthy...

hrp0086p2-p974 | Thyroid P2 | ESPE2016

Severe Growth Retardation and Hypothyroidism due to Hashimoto’s Thyroidits

Krstevska-Konstantinova Marina , Stamatova Ana , Gucev Zoran

Background: Hashimoto’s thyroiditis is a common autoimmune disease in pubertal and adolescent girls. In the past years the incidence of this autoimmune disease of the thyroid gland has increased.Objective and hypotheses: We present a 12.5 year old girl who had her first visit at our Pediatric Endocrinology Department at the age of 10 years due to short stature and clinical signs of hypothyroidism. Her height was – 3SD SDS and her BMI was 12.7. ...

hrp0092p2-300 | Thyroid | ESPE2019

The Encephalopathy as Complication of Hashimoto Thyroiditis in Children: A Wide Variety of Clinical Manifestations

Chiarello Paola , Talarico Valentina , Galati Maria Concetta , Raiola Giuseppe

Hashimoto encephalopathy is an autoimmune encephalopathy predominantly diagnosed in the adult population. In the pediatric population, the mean age is determined to be 14 years, with the majority of adolescent females. The diagnosis of Hashimoto encephalopathy is clinical and based on the highly variable neuropsychiatric conditions, often affecting more than one area of the central nervous system, the detection of antiperoxidase or antithyroglobulin antibodies in serum, and on...

hrp0086p2-p941 | Thyroid P2 | ESPE2016

Celiac Disease in Children and Adolescents with Hashimoto Thyroiditis

Tuhan Hale , Isik Sakine , Abaci Ayhan , Simsek Erdem , Anik Ahmet , Anal Ozden , Bober Ece

Background: Hashimoto thyroiditis (HT) is part of the spectrum of autoimmune thyroid diseases and is characterized by the destruction of thyroid cells by various cell- and antibody-mediated immune processes.Objective and hypotheses: The aim of this study was to evaluate clinical and laboratory findings and determine the prevalence of celiac disease (CD) in children with HT.Method: A total of 80 patients with positive anti-thyroid a...

hrp0086p2-p951 | Thyroid P2 | ESPE2016

Hashimoto’s Thyroiditis in Childhood: An 8 Year Experience

Oikonomakou Maria-Zoi , Oikonomou Maria-Irini , Giannopoulou Sotiria , Filias Athanasios , Krokidas Georgos , Iliopoulou Maria

Background: Hashimoto’s thyroiditis (HT) is the most common thyroid disorder in the pediatric population.Objective and Hypotheses: The aim of the present study was to observe clinical manifestations, clinical course and long term outcomes of HT in children and adolescents.Method: A total of 110 children and adolescents who presented to our center from 2008–2015, were evaluated retrospectively. Age and gender of the patien...

hrp0084p1-129 | Thyroid | ESPE2015

Intelligence and Behaviour in Children and Adolescents with Hashimoto’s Thyroiditis

Boettcher Claudia , Brosig Burkhard , Windhaus Henriette , Wudy Stefan A , Hahn Andreas

Background: Hashimoto’s thyroiditis (HT) is an autoimmune-mediated disorder, and is the most common cause of thyroid disease and acquired hypothyroidism in children and adolescents. In adults with HT, concentration problems, memory disorders and an increased rate of depression have been reported.Objective and hypotheses: To investigate, whether children and adolescents with HT have more behaviour and emotional problems, and/or lower intelligence tha...