hrp0098rfc1.5 | Diabetes and Insulin | ESPE2024

Evaluation of Arterial Stiffness in Children with Type 1 Diabetes Mellitus Using Speckle Tracking Carotid Strain Ultrasonography: Do Atherosclerotic Changes Begin in Childhood?

Gök Mustafa , Deveci Sevim Reyhan , Öztürk Sercan , Ünüvar Tolga , Anık Ahmet

Objective: The aim of this study was to evaluate the effectiveness of the Speckle Tracking Carotid Strain (STKS) ultrasonography technique, which allows the measurement of arterial stiffness and strain parameters, in the detection of early atherosclerotic findings in children with type 1 diabetes mellitus (T1DM).Materials and Methods: Children aged 7-18 years with T1DM and no other comorbidities were included in the stud...

hrp0098p2-42 | Bone, Growth Plate and Mineral Metabolism | ESPE2024

The etiological distribution of elevated serum alkaline phosphatase levels and characteristics of children with transient hyperphosphatasemia

Bahar Balaban Berber İlkay , Öztürk Sercan , Güneş Sebla , Tekneci Ayşegül , Ünüvar Tolga , Anik Ahmet

Objective: Elevated serum alkaline phosphatase (ALP) levels in pediatric patients can result from various etiologies, with transient hyperphosphatasemia, bone pathologies, and hepatic diseases being the most common. This study aimed to elucidate the etiological factors responsible for elevated ALP levels and to evaluate the clinical presentations of transient hyperphosphatasemia in these patients.Materials and Methods: T...

hrp0098p2-69 | Diabetes and Insulin | ESPE2024

Venous Sodium, Potassium, and Glucose Results on Rapid Arterial Blood Gas Analyzer in Children with Diabetic Ketoacidosis: Are the Values Comparable with Results Obtained from the Central Laboratory?

Güneş Sebla , Öztürk Sercan , Şafak İlhan , Deveci Sevim Reyhan , Ünüvar Tolga , Anık Ahmet

Introduction: This retrospective study aim ed to assess the correlation between whole blood electrolytes measured by an arterial blood gas analyzer and serum electrolytes measured at a central laboratory, of patients with diabetic ketoacidosis (DKA).Materials and Methods: Children (1-18 years old) with DKA, followed up at Aydın Adnan Menderes University Faculty of Medicine Hospital between January 2017 and August 2...

hrp0098p1-238 | Fat, Metabolism and Obesity 4 | ESPE2024

Predictive Value of Impulse Oscillometry and Hepatic Fat Content for Obstructive Sleep Apnea Syndrome in Obese Children and Adolescents

Öztürk Sercan , Oğan Akyıldız Utku , Gök Mustafa , Eryılmaz Aylin , Erge Duygu , Ünüvar Tolga , Deveci Sevim Reyhan , Güneş Sebla , Anık Ahmet

Objective: This study aims to assess the potential predictive value of impulse oscillometry (IOS) and hepatic fat content as an alternative diagnostic tools to polysomnography (PSG) for obstructive sleep apnea syndrome (OSAS) in obese children and adolescents.Method: The study included obese children with a body mass index (BMI) above the 95th percentile. OSAS was assessed via PSG in obese children. Hypopnea was defined ...

hrp0098p2-285 | Thyroid | ESPE2024

Levothyroxine poisoning in children is usually benign: A multi-center experience from Turkey

Şen Küçük Kübra , Demir Şule , Deveci Sevim Reyhan , Akgül Fatma , Yalçın Gülşen , Eser Öznur , Bal Alkan , Ergün Elif , Öztürk Sercan , Anık Ahmet

Objective: The objective of this study was to investigate the clinical presentations, laboratory findings, treatment modalities, follow-up strategies employed for children with levothyroxine (LT4) poisoning.Materials-Methods: The study encompassed patients admitted to the respective centers between 2010-2023, who fulfilled the predefined study criteria. Findings were presented as percentages (%), median values with inter...

hrp0086p2-p875 | Syndromes: Mechanisms and Management P2 | ESPE2016

Tricho-Rhino-Phalangeal Syndrome Type I in a Girl with Growth Hormone Deficiency

Cakir Meltem Didem , Altintas Zuhal , Bozdogan Sevcan Tug

Tricho-rhino-phalangeal syndrome Type I (TRPS I) is a rare autosomal dominant genetic disorder clinically characterized by craniofacial and skeletal abnormalities, associated with cone-shaped epiphyses, brachydactyly and short stature. Although patients with TRPS I present various degrees of short stature, there are only four reports of growth hormone deficiency in patients with TRPS I. We present the case of TRPS I and partial GH deficiency. A 15-year-old female was referred ...

hrp0098t8 | Top 20 Posters | ESPE2024

Predicting the risk of fragility fractures in childhood hematologic cancer survivors

Cima Luminita-Nicoleta , Iustina Grosu , Oprescu Raluca , Soare Iulia , Gabriela Barbu Carmen , Colita Anca , Jercan Cristina , Serbanica Andreea , Fica Simona

Background: Childhood hematologic malignancies are no longer a death sentence. With survival rates significantly increasing, focus needs to shift towards diminishing long-term adverse effects, such as bone disorders. In childhood hematologic cancer survivors (CHCS), peak bone mass is not usually attained due to malginancy-related inflammation, treatments employed or subsequent endocrine complications. Thus, low BMD is frequent. However, in the absence of fragi...

hrp0092p1-330 | Diabetes and Insulin (2) | ESPE2019

Evaluation of Clinical, Laboratory and Therapeutic Features and Long Term Follow-up Results in 44 Cases with Genetic Diagnosis of MODY; Single Center Experience

Ozalkak Servan , Keskin Meliksah , Çetinkaya Semra , Erdeve Senay Savas , Bayramoglu Elvan , Aycan Zehra

Introduction-Aim: MODY;It is an autosomal dominant, rare type of diabetes that occurs in young people as a result of mutations of beta cell function and genes involved in insulin secretion. The cases may be misdiagnosed as Type1 and Type2 diabetes. Considering that MODY is clinically and genetically heterogeneous, the findings should be evaluated correctly. It is important to define the clinical-laboratory characteristics of diagnosis and follow-up of patients...

hrp0092p1-342 | Fat, Metabolism and Obesity (2) | ESPE2019

Can Increased First Hour Glucose Concentration in OGTT Be a New Indicator in Projecting Metabolic Profile?

Sahin Nursel Muratoglu , Yilmaz Aslihan Arasli , Özalkak Servan , Aycan Zehra

Aim: Recent studies have shown that the first hour glucose concentration of ≥155 mg / dL in the oral glucose tolerance test (OGTT) in adults with normal glucose tolerance (NGT) may be a strong marker for the development of diabetes, and also an increase in subclinical inflammation, insulin resistance, dyslipidemia and serum transaminases. These results indicate that adults with NGT have increased risk of developing cardiovascular disease and non-alcoholi...

hrp0092p2-234 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Evaluation of Clinical Features and Treatment Responses of Cases with Hyperprolactinemia

Özalkak Servan , Bayramoglu Elvan , Savas Erdeve Senay , Çetinkaya Semra , Aycan Zehra

Aim: In this study, we planned to evaluate the patients with hyperprolactinemia etiology, clinical features and treatment responses.Material and Method: We evaluated retrospectively the features, clinical follow-up data and treatment responses of the patients with hyperprolactinemia in our pediatric endocrinology clinic between 01.01.2012-31.12.2018.Results: Thirty-one patients wit...