ESPE Abstracts

Background: Chronic kidney disease (CKD) was defined by structural or functional renal abnormalities, or an estimated glomerular filtration rate (GFR) of less than 60 mL/min per 1.73 m2. A child with CKD may develop many complications such as: anemia, poor growth and nutrition, bone and mineral disorders, cardiovascular complications, and complications of hemodialysis, and peritoneal dialysis.Aim: Assessment of severity ...

Background: Electrophysiological techniques allowed identification of sub-clinical pathological changes and early diagnosis of diabetic peripheral neuropathy (PN). Neopterin is a marker of inflammation and cellular immune response that is elevated in conditions of T-cell or macrophages activation. Diabetic peripheral neuropathy (PN) is associated with inflammatory/immune processes and therefore, we hypothesized that neopterin could be used as a marker of neuropathy in type 1 d...

Background: The etiology of infantile colic is unknown. Its timing overlaps with that of minipuberty. To the best of our knowledge, the relationship between these entities has not been investigated. In this study, we aimed to assess the relationship between minipuberty and infantile colic by measuring the levels of sex steroids in saliva among infants with and without infantile colic.Methods: Saliva samples were collecte...

Pituitary hyperplasia (PH) is absolute increase in the number of one or more adenohypophyseal cell subtypes, manifesting radiologically as pituitary enlargement beyond what is considered normal. Diagnosis of PH remains predominantly clinical, hormonal, and radiological. Case presentation: we present a clinical course, diagnosis, and management of a case of pituitary gland hyperplasia in 10 years old Egyptian girl, one of twins who sought medical advice when the mother noticed ...

Obesity is a state of imbalance between food intake and energy expenditure leading to a positive energy balance. This condition may be due to the existence of a genetic syndrome: the Prader-Willi syndrome (PWS) is the genetic cause the most common obesity and Laurence-Moon Bardet-Biedl syndrome (BBS), autosomal recessive.Objectives: Our objective is to compare the cardio-metabolic risk factors in children with obesity gene to those of ch...

Introduction: Epidemiological data suggest that obesity was associated with increased risk of renal injury in children.Objective: To assess urinary podocalyxin in obese children and adolescents as a marker of obesity related kidney disease (ORKD) compared to urinary albumin creatinine (A/C) ratio as the standard marker of glomerular injury.Methodology: This case-control study inclu...

Introduction: There is still a debate on the effect of combined treatment with growth hormone (GH) and a luteinizing hormone-releasing hormone (LHRH) analog versus GH alone on final adult height in children with idiopathic short stature (ISS) and those who have early pubertal development at a short height.Case Report: We studied two sisters with a history of familial short stature, early puberty and advanced bone age at ...

Objective: The A1C assay, expressed as the percent of hemoglobin that is glycated, measures chronic glycemia and is widely used to judge the adequacy of diabetes treatment and adjust therapy. Day-to-day management is guided by self-monitoring of capillary glucose concentrations (milligrams per deciliter or millimoles per liter) as well as by using continuous glucose monitoring systems (CGMS). We found a mathematical relationship between A1C and average glucose (AG) levels meas...

Background: Diabetic ketoacidosis (DKA) is a common, life-threatening complication of type 1 diabetes (T1D). Insulin deficiency impairs lipoprotein lipase (LPL) resulting in elevated serum triglycerides (TG) that usually normalize after establishing IV insulin.Objectives: To study the prevalence of hypertriglyceridemia during DKA in T1D patients and assess its relation to DKA severity and glycemic control after 3 months.Methodology...

Due to recent scientific progress in assisted reproductive techniques (ART), infertile couples can now become fertile. Thus, a number of infants in our country are the results of these costly interventions. This study has been undertaken to evaluate the physical growth of ART infants using standard growth charts from birth until 18 months of age.Methods: We measured the anthropometric data of 100 infants newborns conceived through ART intracytoplasmic sp...