hrp0089p2-p199 | Fetal, Neonatal Endocrinology and Metabolism P2 | ESPE2018

Evaluation of Vitamin D Status and Its Correlation with Gonadal Function in Children at Mini-puberty

Kılınc Suna , Atay Enver

Objective: Most recent evidence from conducted in human and animal studies suggests that vitamin D has a potential role in the physiology of reproductive function in both genders. We investigate the role of vitamin D in male and female gonadal function at mini-puberty period with particular emphasis on production of sex steroids and gonadal peptide hormones. Additionaly, this study evaluated serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradio...

hrp0082p2-d2-296 | Bone (1) | ESPE2014

Determinants of Vitamin D Levels in Italian Children and Adolescents of Mugello, an Area of Tuscany: a Longitudinal Evaluation

Scalini Perla , Stagi Stefano , Iurato Chiara , Manoni Cristina , Pelosi Paola , Capirchio Laura , de Martino Maurizio , Seminara Salvatore

Background: Few studies have assessed 25-hydroxy vitamin D [25(OH)D] status among Italian children.Objective and hypotheses: To assess 25(OH)D in children and adolescents living in Tuscany, Italy, identifing risk factors for vitamin D deficiency in different age groups.Method: We evaluated 446 children children and adolescents (2.4–17.8 years), from Mugello (latitude 44° N), and we determined 25(OH)D, calcium, alkaline ph...

hrp0097p1-448 | Fat, Metabolism and Obesity | ESPE2023

The Association between Vitamin D deficiency and Hepatosteatosis in Obese Children and Adolescents. (Underreview in Hormone Research Journal- HRP-2023-1-19)

Anil Korkmaz Huseyin , Bhushan Arya Ved , Barisik Vatan , Atila Dincer , Coskunol Fulya , Alci Serra , Ertug Cekdemir Yasin , Torlak Derun , Ozkan Behzat

Objective: To compare the serum 25-hydroxy Vitamin D [25(OH)D] concentrations in children and adolescents with obesity with and without hepatosteatosis, and investigate the relationship between serum 25(OH)D concentrations and severity of hepatosteatosis. We also aimed to assess the effect of vitamin D treatment after 6 months on hepatosteatosis and liver biochemistry.Methods: One hundred thirty-three obese patients with...

hrp0089p3-p046 | Bone, Growth Plate & Mineral Metabolism P3 | ESPE2018

The Level of the Vitamin D and Bone Mineral Density in Children with Obesity

Mikhno Hanna , Solntsava Anzhalika , Vasilieva Natalia , Dashkevich Helena

Objective: To evaluate bone mineral density (BMD) and its relationship with vitamin D in children with obesity.Methods: We examined 110 children in the University Hospital (Minsk) from 2015 to 2018 yrs. Their anthropometric parameters (height, weight, body mass index (BMI)) were determined. Body composition with evaluating of mineral component were made by dual energy X-ray absorptiometry with the calculation of feet, hands, spine, ribs, hips BMD (g/cm<s...

hrp0086p2-p164 | Bone &amp; Mineral Metabolism P2 | ESPE2016

Vitamin D Dependent Rickets Type II in Saudi Children

Alashwal Abdullah , Aldhalaan Waheeb , Abbas Bassam Bin

Background: Vitamin D dependent rickets type II (VDDR II) is a rare autosomal recessive disorder, inherited due to mutation on vitamin D receptor (VDR) leading to end organ unresponsiveness to vitamin D. It is characterized by an early onset refractory rickets, hypocalcaemia, hypophosphatemia, growth retardation, hyperparathyroidism and elevated circulating levels of 1,25-dihydroxyvitamin D3 which is the hallmark of the disease.Objective and hypotheses: ...

hrp0084p2-230 | Bone | ESPE2015

The Relationship between Serum 25-Hydroxy Vitamin D and Parathyroid Hormone in Children

Kim Hae Soon , Kang Jung In , Han Ye Jin

Background: The lack of agreement in the definition of vitamin D deficiency may be due to differences in the study populations or in the assays used to measure 25OHD.Objective and hypotheses: The aim of this study is to evaluate the relationship between 25OHD and PTH, and define the level of vitamin D deficiency in a paediatric population.Method: Retrospective medical record of children (age: 0.1–18years, n=193) who v...

hrp0082p2-d2-431 | Growth Hormone (1) | ESPE2014

Vitamin D Concentrations in Children with GH Deficiency During First Year of GH Treatment

Pyrzak Beata , Witkowska-Sedek Ewelina , Kucharska Anna , Sagala Magdalena , Majcher Anna

Introduction: The start of GH (rhGH) treatment in children with GH deficiency (GHD) causes a significant increase in bone turnover and increases height velocity. The increase in IGF1 concentrations during rhGH treatment is a marker of the efficiency of treatment. A significant increase in bone turnover during rhGH treatment results in an increased demand for vitamin D. It is important to determine proper supplementation doses of vitamin D in patients during catch-up growth.</p...

hrp0084p3-660 | Bone | ESPE2015

4 Years Follow-Up for 25OHD and iPTH in Vitamin D Substituted Patients with Diabetes Mellitus 1: An Unicentric Prospective Study

Weissenbacher Claudia , Roeb Julia , Sydlik Carmen , Pozza Susanne Bechtold Dalla , Marx Michael , Schmidt Heinrich

Background: Vitamin D deficiency/insufficiency seems to occur frequently in children and teenagers but it is a matter of debate if limits (<20 ng/ml; <30 ng/ml) are correct. Besides its effect in bone metabolism Vit-D is also supposed to have a positive influence in diabetes mellitus 1 (DM1).Objective and hypotheses: To study 25OHD and iPTH values in a group of patients (pts) (n=57) with DM1 without Vit-D substitution (2011), with 1000 I...

hrp0082p2-d2-302 | Bone (1) | ESPE2014

Plasma 25-OH Vitamin D and pth Concentrations in Cord Blood: relationship with Ethnic Groups, Nutritional Habits and Degree of Maternal Sun Exposure

Ortigosa Gomez Sandra , Garcia Algar Oscar , Mur Sierra Antonio , Ferrer Costa Roser , Carrascosa Lezcano Antonio , Yeste Fernandez Diego

Introduction: Several studies showing a high prevalence of vitamin D deficiency in pregnant women have been published in recent years. Vitamin D deficiency during pregnancy has been related to adverse events both in mother and child. Plasma 25-OH vitamin D (25(OH)D) levels in the newborn are dependent on maternal deposits and show a close correlation with maternal levels; thus, neonates of vitamin D-deficient mothers present a greater risk of hypocalcaemia, rickets and a highe...

hrp0084p2-238 | Bone | ESPE2015

Can Vitamin D Deficiency Cause Prolongation in Visual Evoked Potentials?

Dogan Murat , Aydin Ilyas , Kaba Sultan , Bala Keziban Asli , Gulpinar Ozlem

Objective: It is known that vitamin D has differential roles in cell proliferation, differentiation, neurotransmission and neuroplasticity in nervous system and exerts neurotrophic and neuroprotective effects. In recent studies, it was shown that vitamin D could be protective against in age-related macular degeneration and optic neuritis related to demyelinating disorders. Here, we aimed to perform visual evoked potential (VEP) studies before treatment in patients with rickets...