ESPE Abstracts

Background: Precocious puberty (PP) is one of its variations which defines as appearance of physical signs of sexual development in a child prior to the earliest accepted age of sexual maturation, 7 years in girls and 9 years in boy. The exact mechanisms and genetic background of ICPP are not well understood. It is suggested that the kisspeptin neuropeptide, encoded by the KISS1 gene, could have role in this regard.Objective and hypotheses: Considering t...

Background: Neonatal thyroid screening is considered one of the best cost-effective tool to prevent mental retardation in population. Different strategies are suggested for thyroid hormone estimation in the sample obtained at birth using cord blood or later in neonatal period. In King Abdulaziz Medical City, cord TSH is the screening tool to detect congenital hypothyroidism cases with a cut off value of 30 MIU/l considered positive result. In 2011, newborn screening programme ...

Introduction: Diabetic ketoacidosis (DKA) is a common medical emergency and is the most common cause of death in children with type 1 diabetes mellitus due its complications. Paediatric residents are usually the first line whom managing paediatric emergencies in Iraqi hospitals. They form the backbone of the provided service. It is important to make sure they are practicing at the highest possible standard to ensure patients’ safety. Therefore, it is cruc...

Key words: Childhood, Obesity, Periaortic fat thickness, Echocardiography, Cardiovascular risk.Aim: To assess the periaortic fat thickness (PAFT) by echocardiograpy in a cohort of children with simple obesity and to evaluate its relationship to clinical and metabolic cardiovascular risk factors.Methods: Fifty children and adolescents with simple obesity and 25 healthy sex and age m...

Introduction: Data on BP in children with classic congenital adrenal hyperplasia (CAH) is inconsistent.Aim: To assess the trend in BP throughout childhood using data from the International CAH registry and compare this to normative data from the American Academy of Paediatrics (AAP).Method: This retrospective multi-centre study included 37 centres from 20 countries. BP data was ana...

Introduction: The conventional approach to the treatment of Beta- thalassemia major (BTM) is based on the correction of hemoglobin status through regular blood transfusions and iron chelation therapy for iron overload. Allogeneic hematopoietic stem cell transplantation (HCT) remains the only currently available technique that has curative potential. No previous study compared the long-term growth and endocrinopathy changes among large cohorts of BTM patients o...

Background: Metabolic syndrome (MetS) is related to increased cardiovascular complications of obesity. The triglyceride-glucose (TyG) index is frequently used as an indicator of insulin resistance in adults. However, there is scant information on the TyG index in the morbidly obese Pediatric population, nor is its correlation with the components of the metabolic syndrome (MetS).Methods: We compared the use of TyG vs athe...

Obesity is a state of imbalance between food intake and energy expenditure leading to a positive energy balance. This condition may be due to the existence of a genetic syndrome: the Prader-Willi syndrome (PWS) is the genetic cause the most common obesity and Laurence-Moon Bardet-Biedl syndrome (BBS), autosomal recessive.Objectives: Our objective is to compare the cardio-metabolic risk factors in children with obesity gene to those of ch...

Introduction: Epidemiological data suggest that obesity was associated with increased risk of renal injury in children.Objective: To assess urinary podocalyxin in obese children and adolescents as a marker of obesity related kidney disease (ORKD) compared to urinary albumin creatinine (A/C) ratio as the standard marker of glomerular injury.Methodology: This case-control study inclu...

Introduction: There is still a debate on the effect of combined treatment with growth hormone (GH) and a luteinizing hormone-releasing hormone (LHRH) analog versus GH alone on final adult height in children with idiopathic short stature (ISS) and those who have early pubertal development at a short height.Case Report: We studied two sisters with a history of familial short stature, early puberty and advanced bone age at ...