hrp0097p1-157 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Girls born small for gestational age may have an earlier pubertal development comparing to girls born appropriate for gestational age

Nicolas Georges , Haddad Nicolas

Key words: girls, small for gestational age, thelarche, pubarche, menarche.Background: Small for gestational age (SGA) babies are more prone to have an earlier onset of pubertal development and menarche. We conducted a study comparing the first menarche of small for gestational age (SGA) to appropriate for gestational age (AGA) girl newborns.Objective: The objective of the study is...

hrp0092p2-117 | Fat, Metabolism and Obesity | ESPE2019

Trends in Childhood Obesity, Underweight and Short Stature Among Urban School Children in Romania

Pop Raluca-Monica , Neagu Nicolae , Pascanu Ionela

Background: Childhood adolescence overweight and obesity are increasing in Romania, but limited information is available on their current trends.Aim: the current study aimed to analyze the trend in prevalence of weight disturbances and stunting in the past 5 years in school aged children from the Transylvania region in Romania.Material and Methods: Two cross-sectional data sets fro...

hrp0095p1-358 | Pituitary, Neuroendocrinology and Puberty | ESPE2022

Pathogenic and Low-Frequency genetic determinants in children with Central Precocious Puberty

Fanis Pavlos , Toumba Meropi , A Tanteles George , Iasonides Michalis , C Nicolaides Nicolas , Nicolaou Stella , Kyriakou Andreas , Neocleous Vassos , A Phylactou Leonidas , Skordis Nicos

Background: Central precocious puberty (CPP) due to premature activation of GnRH secretion results in early epiphyseal fusion and to a significant compromise in the achieved final adult height as well as psychological consequences. So far only a limited number of genetic determinants have been associated with the pathogenesis in children with CPP. In this original research, rare sequence variants in MKRN3, DLK1, KISS1, and KISS1R genes were i...

hrp0095p1-284 | Fat, Metabolism and Obesity | ESPE2022

Impact of bariatric surgery on newborn growth parameters.

Rayen Aoun , Georges Nicolas

Background: Maternal obesity is known to have many detrimental effects on pregnancy. Bariatric surgery represents the most efficient therapy for severe obesity. Although it is known to positively impact many pregnancy outcomes, bariatric surgery can disturb fetal growth due to nutritional deficiencies.Objective: We aim to examine the repercussions of bariatric techniques on fetal growth, and to evaluate the risk of deliv...

hrp0097p1-84 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2023

Impact of bariatric surgery on newborn growth parameters

Nicolas Georges , Aoun Rayen

Keywords: Bariatric surgery, Pregnancy, Maternal obesity, Small for gestational age, fetal growth, Nutritional deficiencies.Background: Maternal obesity is known to have many detrimental effects on pregnancy. Bariatric surgery represents the most efficient therapy for severe obesity. Although it is known to positively impact many pregnancy outcomes, bariatric surgery can disturb fetal growth due to nutritional deficienci...

hrp0097p1-94 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2023

Thyroid function in small for gestational age and appropriate for gestational age preterm infants admited to the NICU at Notre Dame Des Secours - University Medical Center

Nicolas Georges , Achkar Joy

Keywords: Preterm newborn, Small for gestational age, Thyroid hormones, Thyroid-stimulating hormone, Thyroid dysfunctions, Thyroid function tests.Background: A common cause of neurodevelopmental impairment in children is congenital hypothyroidism, but can be preventable with adequate screening and proper management. Preterm newborns are more likely to have thyroid dysfunction, with small for gestational age (SGA) being a...

hrp0097p1-284 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2023

Neonatal hypoglycemia at one and four hours of life: incidence and associated factors

Nicolas Georges , Khalil Rita

Key words: neonates, hypoglycemia, size for gestational age, gender, mode of delivery.Introduction: Neonatal hypoglycemia is one of the most common treatable metabolic disorders. Universal newborn screening for hypoglycemia is primordial in detecting persistent hypoglycemia and asymptomatic episodes in order to save neonates from adverse neurological outcomes and brain injury.Objectives:</s...

hrp0097p1-487 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2023

The Association of Maternal Pre-pregnancy BMI and Gestational Weight Gain on the Course of Pregnancy and Some Neonatal Parameters

Nicolas Georges , Rouhana Saly

Keywords: Pre-pregnancy BMI, gestational weight gain, pregnancy outcomes, neonatal outcomes.Background: Overweight and obesity epidemic is still expanding, and it is affecting women of childbearing age. Multiple studies have shown unmatched results concerning the effect of Body Mass Index (BMI) besides gestational weight gain (GWG) on pregnancy and neonatal outcomes.Objectives: Thi...

hrp0097p2-181 | Diabetes and Insulin | ESPE2023

Demographic and clinical characteristics of children with type 1 diabetes mellitus at Notre Dames Des Secours University Medical Center Byblos Lebanon

Nicolas Georges , Topalian Raphael

Keywords: Retrospective descriptive study, diabetes mellitus type 1, diabetic ketoacidosis, NDS-UMC, Byblos, Lebanon, single-center experience.Background: Type 1 diabetes mellitus (T1DM) increases worldwide especially in the Mediterranean region. Epidemiological studies about T1DM are made in many countries, but Lebanon lacks such data.Objective: This is a descriptive study of demo...

hrp0097p1-301 | GH and IGFs | ESPE2023

Outcome of growth hormone treatment in growth hormone deficient children over the course of 3 years in Notre Dames Des Secours-University Medical Center Byblos-Lebanon-single center experience

Nicolas Georges , El Kortbaoui Anthony

Key words: Descriptive study, short stature, Growth Hormone deficiency, Growth Hormone analogue, Lebanon, NDS-UMC, Byblos, single center experience.Background: There is a lack of national data concerning growth hormone deficiency treatment in Lebanon. The aim of this study is to describe the height gained under growth hormone therapy of 39 patients diagnosed with growth hormone deficiency (GHD).<st...