ESPE Abstracts

Background: A child with slow growth rate (<−2 SDS) polyuria and polydipsia warrants urgent investigation for hypothalamic–pituitary tumors.Objective and hypoyhesis: To present the case of a boy with slow growth rate, polyuria NAD polydipsia due to remnant craniopharyngeal duct.Method: Boy 11 years old, was evaluated because of short stature and slow growth rate documented for 2 years. He reported no headaches but he...

Background: Carriers of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21-OHD) demonstrate increased secretion of cortisol precursors following ACTH stimulation, suggestive of impaired cortisol production, and compensatory increases in hypothalamic CRH secretion. Both cortisol and CRH have behavioural effects, and hypothalamic CRH hypersecretion has been associated with chronic states of anxiety and depression.Objective and hypoth...

Background: Congenital Hyperinsulinism (CHI) is the commonest cause of persistent neonatal hypoglycaemia and is characterised by inappropriately detectable plasma insulin during hypoglycaemia. Management depends on the timely analysis of biochemical parameters, which would help initiate appropriate management and avoid potential neurological compromise. The technical difficulties in sending the appropriate sample and the delay in processing the sample in the lab sometimes cont...

Background: Obesity in childhood and adolescence represents one of the main health problems of the 21st century. Fibroblast Growth Factor 23 (FGF-23) and its co-receptor, Klotho, play an important role in mineral metabolism, however, little is known about their role in obesity.Objective and Hypothesis: To determine the concentrations of FGF-23 and Klotho in children and adolescents with overweight and obesity.<p class="abs...

Introduction: Obesity in childhood and adolescence has been recognized by the WHO as a global epidemic and a major public health problem. Greece, is one of the main countries in Europe where the problem of childhood obesity has increased rapidly. This rise can be attributed to dietary and physical activity risk factors. Recently, there has been a need for a detailed recording and assessment of the lifestyle habits of children and adolescents receiving personal...

Introduction: Obesity in childhood and adolescence is a major problem with many adverse consequences in public health due to its increasing prevalence, as well as the burden on the health system. Recently, the need to find effective intervention and prevention strategies for the management of obesity has led to the development of e-health technologies, which record behavioral data objectively and correlate them with factors that increase body mass index (BMI)....

Background: Electromagnetic field (EMF) exposure has been considered a potential environmental toxicant, which may influence endocrine and other functions, while population awareness remains limited. In an earlier study, we demonstrated that EMF alters the hypothalamic-pituitary-adrenal axis in children using a 3G mobile telephone.Aim: To screen and compare the motives, knowledge and status of electromagnetic field expos...

This present study investigates the impact of a common environmental hazard, the radiofrequency fields (RF), such as those regarding cell phones, cell phone base stations, wi-fi, portable phones (DECT), etc., as close to the body sources of exposure, on endocrine function. This is of importance, particularly for developing children, that have been and are exposed to this potential hazard. We performed analyses on endocrine assessments regarding stress, thyroid hand reproductiv...

Background: Obesity in childhood and adolescence is often associated with dyslipidemia, hypertension, insulin resistance, inflammation, and disturbances in adipocytokine secretion, which lead to endothelial dysfunction and the development of atherosclerotic cardiovascular disease.Aim: To determine the prevalence of metabolic syndrome (MS) among obese children and adolescents attending our out-patient childhood obesity cl...

Introduction: Exercise has pleiotropic positive effects for children and adolescents with Type 1 Diabetes (T1D). It improves glycemic control, daily insulin requirements, quality-of-life, morbidity and mortality rate. Leptin and adiponectin are adipocytokines produced by adipose tissue cells. Adiponectin is anti-atherogenic, anti-diabetic and anti-inflammatory, whereas leptin induces insulin resistance, has thermoregulatory properties and is pro-inflammatory.<...