ESPE Abstracts

Introduction: The nutritional status of a child is essential for the overall development and in particular for the statural growth. It was previously reported that growth hormone (GH) administration in children with growth hormone deficiency (GHD) could have a beneficial effect on body mass index (BMI) in both underweight and overweight children, suggesting a complex interplay between nutrition and growth. Therefore, the aim of the study was to analyze the influence of BMI on ...

Autosomal dominant cutis laxa type 3 (ADCL3) is a genetic connective tissue disorder characterized by poor pre- and postnatal growth and, rarely, by systemic impairment. The aetiology of short stature is incompletely known, some of these patients reaching normal final height. Less than 50 cases were reported in the literature. We report the case of a male patient 3.2 years old who presented for endocrinological evaluation of short stature. His medical history reveals congenita...

Background: Dystopia thyroid is an anomaly of development and is the result of a violation of embryogenesis and often remains unrecognized, the true frequency of the dystopia of the thyroid gland is not known, described 800 cases of ectopic thyroid gland in the region of blind holes of the tongue in adults and 80 cases in children, half of them diagnosed congenital hypothyroidism.Objective and hypotheses: To reveal some features in the diagnosis and trea...

Background: Intrauterine growth retardation (small for gestational age (SGA)) is connected with perinatal morbidity, neurological pathology and stature.Objective and hypotheses: The aim of our study is to estimate the incidence of SGA and its consequences in newborns and infants at the age 1.Method: The incidence of SGA among newborns in the Udmurt Republic (the region of the European part of the Russian Federation) has been studie...

There is not enough reasoned data on the dynamics of body weight indices in premature infants born small by gestational age (SGA).Aim: To study the nutritional status in premature babies born small by gestational age, in the first 5 years of life.Materials and Methods: The prospective study included preterm infant with SGA (n = 100) and prematurity corresponding to gestational age - AGA (n = 69) w...

Aim: to evaluate the frequency and predictors of short stature in preterm infants born small for gestational age (SGA), by the age of 5 years. Materials and Methods. We examined 100 premature babies (gestational age of 22-31 weeks – 18, 32-36 weeks – 82), born SGA with the tables Fenton T. R. et al. (2013). Protocol included an assessment of anthropometric indicators and IGF-1 levels in the blood at birth, at the ages of 1 and 5 years. The odds ratio...

Background: In this study we investigated the genetic aetiology of a series patients with DSD seen in Ukraine.Materials and Methods: The Ukraine Pediatric DSD Register has 95 children with DSD between the ages of 0-18 y.o. in 2018 (a prevalence of 1 in 80097). The criterion for including patients to the database was ambiguous genitalia and/or a discrepancy between the chromosomal and gonadal/genital sex. All patients had...

Introduction: The pathology of thyroid gland is Ukraine is quite common and in 2018y included 277,708 patients with diffuse goiter (36.47 per 1000 population), 2,311 patients (0.30:1000) with nodular goiter, 341 patients with diffuse toxic goiter (0.04:1000), 7,157 (0.94:1000) with autoimmune thyroid disease and 129 patients with thyroid cancer (1.7:100000). However the syndrome of resistance to thyroid hormone (RTH) or Familial Dysalbuminemic Hyperthyroxinemi...

Introduction: The birth of a child with disorders of sex development (DSD) requires a long-term strategy of monitoring and treatment which is carried out by a multidisciplinary group of professional physicians, with a mandatory understanding of the psychosocial problems in a child and parents.Materials and Methods: Gender self-identification was investigated in 20 children and adolescents with DSD aged 1.5-17 years. To d...

Background: The term ‘disorder of sex development’ (DSD) includes congenital conditions in which development of chromosomal, gonadal or anatomic sex is atypical.Materials and methods: A retrospective analysis of the 75 medical cards of patients with DSD since 2000 up to 2017 year was done. The criterion for including patients to the database was ambiguous genitalia and/or a discrepancy between the chromosomal and gonadal/genital sex. At the tim...