hrp0082p2-d2-296 | Bone (1) | ESPE2014

Determinants of Vitamin D Levels in Italian Children and Adolescents of Mugello, an Area of Tuscany: a Longitudinal Evaluation

Scalini Perla , Stagi Stefano , Iurato Chiara , Manoni Cristina , Pelosi Paola , Capirchio Laura , de Martino Maurizio , Seminara Salvatore

Background: Few studies have assessed 25-hydroxy vitamin D [25(OH)D] status among Italian children.Objective and hypotheses: To assess 25(OH)D in children and adolescents living in Tuscany, Italy, identifing risk factors for vitamin D deficiency in different age groups.Method: We evaluated 446 children children and adolescents (2.4–17.8 years), from Mugello (latitude 44° N), and we determined 25(OH)D, calcium, alkaline ph...

hrp0094fc7.2 | Fetal Endocrinology and Multisystem Disorders | ESPE2021

Maternal, rather than fetal, genetic variation in vitamin D metabolism is associated with umbilical cord blood 25-hydroxyvitamin D in pregnancies supplemented with cholecalciferol: findings from the MAVIDOS randomized controlled trial

Moon Rebecca , D’Angelo Stefania , Curtis Elizabeth , Cooke Laura , Davies Justin , Crozier Sarah , Godfrey Keith , Graham Nikki , Holloway John , Lewis Rohan , Cleal Jane , Inskip Hazel , Cooper Cyrus ,

Background: Neonatal vitamin D deficiency (VDD) can result in symptomatic hypocalcemia, seizures and cardiomyopathy and has been associated with reduced bone mineralization in childhood, but is potentially preventable with antenatal cholecalciferol supplementation. Single nucleotide polymorphisms (SNP) in the vitamin D metabolism pathway are associated with serum 25-hydroxyvitamin D [25(OH)D] in adulthood. We assessed whether maternal and/or offspring SNPs in ...

hrp0092p1-174 | Bone, Growth Plate and Mineral Metabolism (1) | ESPE2019

The Optimal Dosage of Vitamin D Supplement for Vitamin D deficiency in Korean Children and Adolescents

Yang Seung , Hee Yi Kyung , Kim Eun Young , Hwang Il Tae

Purpose: Vitamin D deficiency (VDD) is very common nowadays in children as well as in adults, probably due to decreased exposure to sunlight. In Korea, the prevalence of VDD was 47% in teenage boys and 65% in teenage girls. However, the optimal dosage regimen for correcting deficiency is unknown. We investigate the change of serum 25(OH) vitamin D concentration according to the treatment dosage and duration in VDD.Methods...

hrp0092p3-107 | Fat, Metabolism and Obesity | ESPE2019

Relation of Serum 25 Hydroxy-Vitamin Levels D3 with Body-Mass Index in Pediatric Patients

Ventura Wichner Paula Sol , Bosch Zelmira , Grigolato Anabella , Del Valle Rossi Romina , Fornells Eduard , LaCruz Marisa Torres

Background: The aim of our study is to determine the relation of vitamin D levels (25(OH)VD) with body-mass index (BMI), age and month of extraction in pediatric patients.Materials and Methods: We present a retrospective review of medical records of patients under 18 years of age visited by the Children's Endocrinology Service (overweight and obesity) and ambulatory pediatrics (healthy and normal weight children) at ...

hrp0084p3-916 | GH & IGF | ESPE2015

Vitamin D Deficiency can Modulate GH/IGF1 Axis in GH Deficient Children

Witkowska-Sedek Ewelina , Kucharska Anna , Majcher Anna , Pyrzak Beata

Background: According to the latest studies vitamin D has an effect on the production and/or secretion of IGF1 in the liver, but the exact mechanism regulating these relationships has not been thoroughly explained.Objective and hypotheses: Evaluation of the relationship between 25(OH)D and IGF1 levels in the serum of children with GH deficiency (GHD).Method: The study group consisted of 76 GH deficient children qualified for GH the...

hrp0082p3-d1-761 | Fat Metabolism & Obesity | ESPE2014

25-Hydroxy Vitamin D Deficiency and its Relationship to Obesity and Other Risk Factors in a Group of Iranian Children and Adolescents

Moayeri Heshmat , Ghasemzadeh Maral

Background: There is increasing evidence of vitamin D deficiency world-wide resulting in nutritional rickets. With increasing use of fast foods and reducing appropriate physical activity. Our world is encountered with the problem of obesity which increases the risk of 25-hyroxy vitamin D deficiency.Objective and hypotheses: The aim of this study was to determine the status of serum 25(OH)D level in children 2–14 years old who visited in a pediatric ...

hrp0082p1-d2-37 | Bone | ESPE2014

Vitamin D Levels and Effects of Vitamin D Replacement in Children with Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome

Scalini Perla , Stagi Stagi Stefano , Iurato Chiara , Menchini Camilla , Manoni Cristina , Anzillotti Giulia , de Martino Maurizio , Seminara Salvatore

Background: The periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome, is an autoinflammatory disease characterised by regularly recurrent fever episodes, due to seemingly unprovoked inflammation.Objective and hypotheses: The aim of the study was to assess serum 25-hydroxy cholecalciferol (25(OH)D) concentrations in children with PFAPA and to evaluate longitudinally the effect of wintertime supplementation on 25(OH)D st...

hrp0092p3-103 | Fat, Metabolism and Obesity | ESPE2019

Relationship Between 25-Hydroxyvitamin D with Adiposity Assessed by Body Mass Index, Serum Glucose and Lipids Levels in Korea: A Cross-Sectional Analysis

Shim Kye Shik , Cho Ja Hyang , Jung Hae Woon

Purpose: Vitamin D deficiency is thought to be influenced by cardiovascular function and glucose homeostasis, however the potential influence of vitamin D status on insulin resistance, is not well understood. The aim is investigate the correlations between 25-hydroxyvitamin D[25(OH)D] with adiposity assessed by body mass index(BMI), fasting glucose and lipid levels on schoolchildren.Methods: From April 2015 to July 2018,...

hrp0082p3-d2-893 | Perinatal and Neonatal Endocrinology (1) | ESPE2014

Severe Vitamin D Deficiency Among Pregnant Women and Their Newborns in Turkey

Parlak Mesut , Kalay Zuhal , Kirecci Ahmed , Guney Ozgur , Koklu Esad , Kalay Salih

Objectives: Vitamin D deficiency is an important health problem in pregnant women and their infants in sunny countries. The present study evaluated serum 25-hydroxyvitamin D3 (25(OH)D3) concentrations in pregnant women and in their newborns and determined the risk factors in LSES cities in Turkey.Methods: Ninety-seven pregnant women and their newborns were included in the study between December 2012 and February 2013. All of the pregnant women had irregu...

hrp0082p2-d2-295 | Bone (1) | ESPE2014

Determinants of Vitamin D Levels in Children, Adolescents, and Young Adults with Juvenile Idiopathic Arthritis

Stagi Stefano , Capirchio Laura , Marino Achille , Bertini Federico , Seminara Salvatore , de Martino Maurizio , Falcini Fernanda

Background: 25-Hydroxyvitamin D (25(OH)D) deficiency is reported to be common in patients with rheumatoid arthritis and associated with disease activity, physical disability, and cardiometabolic intermediates; data in patients with juvenile idiopathic arthritis (JIA) are inconsistent.Objective and hypotheses: To assess serum 25(OH)D in children, adolescents, and young adults with JIA, and to identify the risk factors for vitamin D deficiency in JIA patie...