hrp0097p2-126 | Diabetes and Insulin | ESPE2023

Relationship Between Time in Range (TIR), Time Below Range (TBR), Time Above Range (TAR), Glycemic Variability (GV), and HbA1c as predictor of glycemic control in children and adolescents with Type 1 Diabetes Mellitus.

Ahmed Shayma , Soliman Ashraf , Hussain Mona , Alyafei Fawzia , Alaaraj Nada , Hamed Noor

Introduction: Glycated hemoglobin (HbA1c) is a rough indicator of glycemic control and not useful to evaluate aspects related to acute or daily glycemic changes in diabetic patients. With the emphasis on intensive management of type 1 diabetes (T1DM), data from studies support using Continuous Glucose Monitoring (CGM) to improve glycemic control and reduce glucose variability, which is related to an increase in macro and microvascular complications.<p clas...

hrp0097p2-67 | Fat, Metabolism and Obesity | ESPE2023

The outcome of management for childhood obesity during COVID19 pandemic (2019-2021) in Qatar

Hamed Noor , Shaat Mona , Soliman Ashraf , Alyafei Fawzia , Alaaraj Nada , Ahmed Shayma

Introduction: Obesity is serious health concern that affect the children during pandemic due to school closing and shifting to online teaching with suspension of almost all physical activity. In addition, many overweight and obese children had irregular meal timing, frequent snacking, and increased screen time at home.Objectives: To study the effect of COVID 19 on weight gain during the lock- down and shifting to online ...

hrp0097p2-47 | GH and IGFs | ESPE2023

The Interaction between Growth Hormone (GH) -Insulin-like Growth factor 1 (IGF1) axis and Immune Systems in Infants and Children During undernutrition: Newly Discovered Pathological mechanisms.

Soliman Ashraf , Alaaraj Nada , Rogol Alan , Alyafei Fawzia , Hamed Noor , Ahmed Shayma , Soliman Nada

Accumulating evidence indicates various interactions between the GH-IGF1 axis and the immune system in infants and children during undernutrition.Objectives and Methods: We performed electronic literature systematic review using PubMed, Google Scholar, and Web of Sciences with the aim to provide an update on the link between the GH-IGF1 axis and the immune system in infants and children during malnutrition. We reviewed 22 studies (2007-2...

hrp0097p2-136 | GH and IGFs | ESPE2023

Human milk insulin-like growth factors and Cyclic glycine-proline (cGP) concentrations in relation to infantile and childhood growth.

Soliman Ashraf , Alyafei Fawzia , Alaaraj Nada , Hamed Noor , Ahmed Shayma , Soliman Nada

Introduction: Insulin-like growth factor (IGF)-1, IGF binding proteins (IGFBPs) and regulatory metabolites, including cyclic Glycine-Proline (cGP), have a possible role in modifying infant growth trajectories through their effects on linear growth, and body composition. There is no consensus on how maternal BMI affects breast milk IGF1 level.Aim: We reviewed the recent literature about human milk (IGF)-1, and cGP concent...

hrp0097p2-161 | GH and IGFs | ESPE2023

Maternal Factors affecting Human milk insulin-like growth factor (IGF) (HMIGF1) level.

Soliman Ashraf , Hamed Noor , Alaaraj Nada , Alyafei Fawzia , Ahmed Shayma , Adel Ashraf

Introduction: Accumulating evidence indicates various but significant effects of human milk IGF1 (HMIGF1) on infantile and childhood linear growth and weight gain. Studies on maternal factors affecting the level of HMIGF1 need to be clarified.Objectives and Methods: We performed electronic literature systematic review using PubMed, Google Scholar, and Web of Sciences with the aim to provide an update on maternal factors ...

hrp0097p2-6 | Growth and Syndromes | ESPE2023

Maternal, placental and fetal IGF-1 and IGFBP in Obese pregnancies and the effect on fetal/infantile growth

Soliman Ashraf , Hamed Noor , Ahmed Shyama , Alyafei Fawzia , Alaaraj Nada , Soliman Nada

Introduction: Placental hormones can control the transfer of maternal nutrients to the fetus and modulate fetal and neonatal growth. Data about the interaction between maternal, placental and fetal IGF1/IGFBP in relation to newborn size is not clear,Aim: To review research paper published in Pubmed, Google scholar, Research gate, and Scopus in the past 20 years on the relation between maternal, placental and fetal/infant...

hrp0097p2-194 | Growth and Syndromes | ESPE2023

Impact of Undernutrition and Short Stature on The Quality of Life (QOL) in Children and adolescents with Beta thalassemia Major (BTM)

Soliman Ashraf , Ahmed Shayma , Soliman Nada , Elalaily Rania , Alyafei Fawzia , Alaaraj Nada , Hamed Noor , Itani Maya

Introduction: Quality of life (QoL), comprises physical, psychological, environmental, and social aspects, is an index designed to measure the burden of chronic diseases and evaluate the treatment outcome. Thalassemia major (BTM) is a chronic disease in children that harms children QoL by interrupting physical function, emotional function, social function, and school function. ObjectivesAim: This study aims to identify t...

hrp0097p2-87 | Multisystem Endocrine Disorders | ESPE2023

Undernutrition, abnormal body composition, and impaired linear growth in children and adolescents with Beta-Thalassemia Major: possible contributing factors

Soliman Ashraf , Ahmed Shayma , Alaaraj Nada , Elalaily Rania , Alyafei Fawzia , Hamed Noor , Soliman Nada

Introduction:Blood transfusion and iron chelation are conventional treatments for β-thalassemia (BTM). Malnutrition negatively affects their growth, efficacy of treatments, and quality of life.Objective: To evaluate the nutritional status and linear growth in 10 countries in the past 20 years.Methods: We performed an electronic search in PubMed, Google Scholar, and Web of Scie...

hrp0095p1-92 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2022

Reference National Standards for Placental Weight in Infants born between the 37th and 43rd weeks of Gestation in Qatar. (A Population-Based Retrospective Data Analysis (n = 80722).

Alyafei Fawzia , Al-qubasi Mai , Soliman Ashraf , Ali Hamdy , Olukade Tawa , Alturk Mohamad , Alaaraj Nada , Hamed Noor , Ahmed Shayma

Introduction: Because of the associations and links between abnormal placental weight and both fetal and maternal disorders, it is important to have the national normal standard for placental weight as a normality reference.Aims: To find out the national placental weight standards for babies born between 37th and 43rd weeks of gestation in all groups of males and females babies born AGA, SGA, and LGA.<p class="abstex...

hrp0095p1-133 | Growth and Syndromes | ESPE2022

Postnatal growth of infants born < 2.5 kg: small for gestational age (SGA) vs appropriate for gestational age (AGA)

Alyafei Fawzia , Soliman Ashraf , AlYousef Doaa , Shaat Mona , Itani Maya , Ali Hamdy , Alaaraj Nada , Hamed Noor , Ahmed Shayma

We studied anthropometric measures (z scores) from birth to 2 years in 115 infants who were born with birth weight <2.5 kg but > 1.5 kg. They were divided into two groups based on Fenton's preterm growth standards at birth. Group 1 (AGA) with weight z score (WAZ) > -2 (n = 100), and group 2 (SGA) with WAZ < -2 (n = 15). Postnatal growth data were evaluated based on the WHO growth standard without correction for prematurity.<p class="abste...