hrp0089p3-p174 | Fetal, Neonatal Endocrinology and Metabolism P3 | ESPE2018

Congenital Hyperinsulinism and Maple Syrup Urine Disease a Challenging Combination

Shidhani Azza Al , Murshedi Fathiya Al , Yaarubi Saif Al , Thihli Khalid Al , Ullah Irfan

Background: Congenital hyperinsulinism (CHI) is the most common cause of persistent hypoglycemia in infancy, characterized by unregulated insulin secretion. CHI is a challenging disease to diagnose and manage. Moreover, complicating the course of the disease with another metabolic disease like Maple syrup urine disease (MSUD) adds more challenges to the already complex management.Case: We report a term male neonate with uneventful birth ...

hrp0082p3-d2-719 | Diabetes (1) | ESPE2014

Arabic Translation and Validation of the Newest Vital Sign Health Literacy Tool: a Pilot Project to Test Health Literacy of Caregivers of Children with Type 1 Diabetes in Kuwait

Al-Abdulrazzaq Dalia , Al-Haddad Muneera , AbdulRasoul Majedah , Al-Basari Iman , Al-Taiar Abdulla

Introduction: Health literacy is a recognized concept in diabetes care. The newest vital sign (NVS) is an English instrument established to test health literacy using a nutrition label. No studies looked into health literacy in the Arab world. Our aim is to translate and validate the NVS tool to Arabic then test it on a pilot of Arabic-speaking caregivers of children with type 1 diabetes.Methods: i) Production of the Arabic version: the English version o...

hrp0094p2-276 | Growth hormone and IGFs | ESPE2021

Growth Hormone Resistance; The Iraqi experience

Al-Jumaili Ali ,

Introduction: Primary growth hormone resistance or growth hormone insensitivity syndrome (Laron syndrome) is an autosomal recessive disorder caused by deletions or mutations in the growth hormone receptor gene or by post receptor defects. Laron is characterized by a clinical appearance of sever growth hormone deficiency with high levels of growth hormone in contrast to low insulin-like growth factor 1 values and in this cases are refractory to both endogenous ...

hrp0097p2-280 | Late Breaking | ESPE2023

Prevalence of Childhood Obesity Among Children Visited Paediatric Outpatient Clinics in Oman - A Single Centre Experience

Al-Lawati Osama , Al-Musharafi Ahmed , Al-Ghafri Shahad , Al-Harthi Hamza , Alsaffar Hussain

Introduction: Childhood obesity is a significant public health concern, affecting over 100 million children worldwide, with an overall prevalence of 13%. A previous Omani study in 2012 suggested the prevalence of childhood obesity in Oman was 12.5%.Objectives: This study aims to identify the prevalence of childhood obesity among children under the age of 13 yrs, who visited various pediatric outpatient clinics at Sultan ...

hrp0086p2-p860 | Syndromes: Mechanisms and Management P2 | ESPE2016

Referral Pattern of Children with Short Stature to a Pediatric Endocrine Clinic in Kuwait

Al-Abdulrazzaq Dalia , Al-Taiar Abdulla , Hassan Kholoud , Al-Twari Basma , Al-Osaimi Abdulaziz , Al-Busairi Iman

Background: Short stature is a prominent complaint for which children are referred to pediatric endocrinologists. Data on short stature is lacking in the Arab states in the gulf region despite the fact that treatment is easily accessible. The study aimed to describe the referral pattern, baseline characteristics, and etiological profile of children referred with short stature to a pediatric endocrine clinic in Kuwait.Method: This is a cross-sectional ret...

hrp0094p2-11 | Adrenals and HPA Axis | ESPE2021

Rare Presentation of Adrenal Insufficiency in an Infant with Holocarboxylase Synthetase Deficiency

Al-Farsi Aws , Qureshi Tabinda Naz , Ullah Irfan , Al-Rahbi Najwa , Abdwani Raghad Al , Al-Musalhi Buthaina , Al-Thihl Khalid , Al-Shidhani Azza , Alsaffar Hussain ,

Introduction: Adrenal insufficiency can be caused by different factors. Biotin deficiency is either nutritional or related to synthesis/recycling defects. We are reporting a rare case of adrenal insufficiency complicating a late diagnosis of holocarboxylase synthetase deficiency in an infant who also had protein-S-deficiency, later thought to be secondary.Case: Term female infant born, to non-consanguineous parents, in good condition wit...

hrp0095p2-115 | Fat, Metabolism and Obesity | ESPE2022

Is it Hyponatremia or Pseudohyponatremia? Management of Low Serum Sodium in Patient with Acute Pancreatitis Secondary to Hypertriglyceridemia

Alsaffar Hussain , Al-Mamari Moza , Al-Mamari Salim , AlShidhani Azza

Background: Hyponatremia is an electrolyte disorder, that may lead to severe complications such as rhabdomyolysis, seizures, coma, and death. Clinicians do take hyponatremia seriously. However sometimes clinicians should be careful in interpreting the low laboratory sodium level as it does not necessarily reflect the actual natremic status especially when the patient is euvolemic and having normal serum osmolality, for which pseudohyponatremia should be consid...

hrp0089p2-p008 | Adrenals and HPA Axis P2 | ESPE2018

Testing Antiandrogens and Aromatase Inhibitors to Achieve Normal Growth in Children with Classical Congenital Adrenal Hyperplasia: A Systematic Review and Meta-analysis

Al Balwi Rana , Al Madani Wedad , Saad Rania , Ferwana Mazen

Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is an autosomal recessive disease in which adrenal synthesis of glucocorticoids and mineralocorticoids is impaired and steroid biosynthesis is directed toward the formation of excessive androgens. Persistently high androgens will accelerate bone maturation and reduce final adult height.Objectives: To assess the efficacy of androgen antagonist Flutamide and aromatase inhibitor Tastolact...

hrp0084p1-92 | Growth | ESPE2015

Chronic Effects of Bisphenol A Administration on Growth Hormone Activity

AL-Masroori Mohammed , Hebais Mohammed , AL-Araimi Amnah , Zadjali Fahad

Background: Bisphenol A (BPA), a plastic byproduct, is a known endocrine disruptor and is types of cancers, such as prostate and ovaries, and some other health conditions, for instance diabetes and obesity. It has direct effect on reproductive system through its strong oestrogen agonist activity.Objective and hypotheses: BPA has a strong oestrogen agonist activity. And oestrogen antagonize cellular activity of growth hormone (GH), however, the effect of ...

hrp0097p1-33 | Diabetes and Insulin | ESPE2023

Health-Related Quality of Life in Children and Adolescents with Type1 Diabetes Mellitus

Alkhouli Laila , Al Remeithi Sareea , Al Jeneibi Sara

Background: HRQoL has been acknowledged as an essential health outcome measure. Studies have shown that enhancing the HRQoL and well-being of children with diabetes is as important as metabolic control in preventing secondary morbidity. Objectives: to evaluate HRQoL of children and adolescents with T1D managed at our institute and investigate factors (patient and disease-related) associated with HQoL scores.Methods: a cr...