hrp0082p3-d3-802 | Gonads and Gynaecology | ESPE2014

The Effects of Rhythmical Massage Therapy and Heart Rate Variability-Biofeedback on Primary Dysmenorrhea a Qualitative Study

Boning Anna , Karutz Aurelia , Vagedes Jan , Berger Bettina , Martin David

Aim: This study investigated rhythmical massage therapy (RMT) and heart rate variability-biofeedback (HRV) to treat dysmenorrhea.Methods: As a part of a randomized controlled trial, 60 patients were allocated to one of the two intervention groups or the crossover control group. For the qualitative study, before and after the 3-month intervention, the women drew their pain into a body silhouette. With the aid of these drawings, half-structured interviews ...

hrp0082p3-d3-872 | Growth (4) | ESPE2014

Descriptive Analyses of Turner Syndrome

Bessahraoui Mimouna , Naceur Malika , Niar Sakina , Zennaki Amel , Arbi Farouk , Ousaleh Meriem , Bouziane-Nedjadi Karim

Background: Turner syndrome (TS) is a genetic syndrome caused by complete or partial absence of an X chromosome. It is the most common diagnosed sex chromosome abnormality in women, affecting 1/2000–2500 female live births.Objective and hypotheses: To determine to establish the clinical, hormonal, cytogenetic, and evolutive pattern of children with TS and to establish for correlations between genotype and phenotype.Method: We ...

hrp0094hdi2.3 | How Do I Session 2 | ESPE2021

Advise patients on insulin dosing for real meals.

Pankowska Ewa ,

In Functional Intensive insulin therapy (FIIT), despite the using injection or continuous subcutaneous insulin infusion (CSII), the golden standard in meal insulin programing is carbohydrate food counting. On the other hand more and more study have shown how fat and protein meals raise postprandial glycaemia for long time than 3 hours. It was also observed that prolonged insulin delivery in normal and square-wave bolus for a mixed meal helps to normalize glycaemia profile if c...

hrp0094p2-454 | Thyroid | ESPE2021

Thyroid dysfunction in small for gestational age infants: a need for second screening?

Park So Yun , Kang Seokjin

Recently there has been studies which reported that SGA could be a risk factor for the development of delayed TSH elevation (dTSH) in preterm infant. To our knowledge, very few studies have addressed development of dTSH in SGA infants whose gestational age > 34. We included 76 SGA infants and 83 controls matched on sex and birth weight who showed normal results on the initial thyroid function screening test. On the following test for thyroid function, dTSH prevalence was ...

hrp0097p1-296 | GH and IGFs | ESPE2023

The efficacy and safety of rhGH treatment combined with letrozole/GnRHa in adolescent boys

Zhang Ying , Chen Ruimin

Objective: In boys during puberty who were undergoing recombinant human growth hormone (rhGH) treatment, we compared the therapeutic efficacy and any adverse reactions, of co-therapy with letrozole/gonadotropin releasing hormone analog (GnRHa).Methods: Fifty-six pubertal growth hormone deficiency (GHD) boys were studied, they were treated with the combination of letrozole and rhGH (letrozole group) or GnRHa and rhGH (GnR...

hrp0097p2-236 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Congenital Hypopituitarism: a pathology not to be ignored

Ould Mohand Ouamer , Drali Ouardia , Khelfat Farah , Mekki Azzedine

Introduction: Pituitary deficiency, or hypopituitarism, is defined by insufficient synthesis of one or more anterior pituitary hormones (growth hormone, TSH, ACTH, LHFSH, prolactin) associated or not with diabetes insipidus (ADH deficiency). In children it is more frequently congenital, due to abnormal pituitary development; it is then a rare disease with an estimated prevalence of between 1/16.000 and 1/150.000.Case report:</str...

hrp0095mte1 | Pediatric Cushing Disease | ESPE2022

Pediatric Cushing disease

By far, the most common type of CS is due to exogenous causes, i.e. medication-induced CS. Endogenous causes are rare by they are all associated with one form of another of a tumor. We call Cushing Disease (CD) what is caused by pituitary adenomas only. It is common for children with CD to show an increase in rate of weight gain accompanied by a decrease in growth rate (linear height) due to decreased growth hormone secretion. This is often easily detected in growth charts of ...

hrp0095fc1.2 | Thyroid | ESPE2022

Comorbidity in congenital hypothyroidism - A nationwide population-based cohort study

Danner Emmi , Jääskeläinen Jarmo , Huopio Hanna , Niuro Laura , Niinikoski Harri , Kero Jukka , Sund Reijo

Aim of the study: The aim of this nationwide population-based register study was to investigate the incidence of congenital malformations, neonatal and chronic comorbidities, and the use of prescribed drugs in patients with primary congenital hypothyroidism (CH).Methods: The study cohort and matched controls were identified from national population-based registers in Finland (The Social Insurance Institution of Finland a...

hrp0095p2-311 | Late Breaking | ESPE2022

A novel 2q12 duplication causes intellectual disability and short stature in a Turkish family

Kocaay Pınar , Tepe Derya , Cevdet Ceylan Ahmet

Copy-number variation (CNV) is a kind of malfunction of DNA polymerase to produce extra genetic material which leads to more number of repeats in genes. CNVs have been associated with different clinical phenotypes, such as learning disabilities, short stature, and intellectual disability. The chromosomal microarray analysis is an effective diagnostic method for identifying new CNVs and understanding their clinical effects. In this case report, a variation that has not been rep...

hrp0092fc2.6 | Bone, Growth Plate and Mineral Metabolism Session 1 | ESPE2019

Validation of a New Version of BoneXpert Bone Age in Children with Congenital Adrenal Hyperplasia (CAH), Precocious Puberty (PP), Growth Hormone Deficiency (GHD), Turner Syndrome (TS), and other Short Stature Diagnoses

Thodberg Hans Henrik , Martin David D

Background: The BoneXpert method for automated determination of bone age from hand X-rays is based on machine learning, so it lends itself naturally to be improved by adding more training data and using better learning algorithms. Currently, version 2 is running in 145 hospitals across Europe, and a new version 3 is rolled out in 2019.Objective and Hypotheses: The aim was to validate version 3 against manual ratings in r...