ESPE Abstracts (2014) 82 P-D-2-1-326

Trends in Incidence and Prevalence of DM Type 1 in Children in Ukraine During 2002-2012

Evgenia Globa & Nataliya Zelinska

Ukrainian Center of Endocrine Surgery, Endocrine Organs and Tissue Transplantation, MoH of Ukraine, Kiev, Ukraine

Background: The aim of the study was to describe the incidence and prevalence trends of diabetes mellitus (DM) type 1 in children of different age groups in Ukraine during 2002–2012.

Objective and hypotheses: Ukraine has a 25 districts, with a population of 45 553 000, including 7 971 638 children.

Method: We analyzed data based on a clinical diagnosis in child population aged 0–17 years old centrally from all regions of Ukraine during 2002–2012. The prevalence and incidence of DM1 were studied in children aged 0–17 years old and in different age groups (0–6, 7–14, and 15–17 years old).

Results: Based on the Ukrainian Pediatric Diabetes Register the number of children with DM1 0–17 years old in 2012 was 8178 (one in 975), with DM2 – 64 (one in 124 557), with neonatal diabetes – 32 reported cases (one in 249 113). Among DM1 group the number of children without chronic complication was 58.3%, HbA1c level was 8.72±1.3% (vs 7.09±1.23% in DM2 group, P<0.05). During 2002–2012 the prevalence and incidence of DM1 in pediatric population 0–17 years old has greatly increased from 7.77 to 10.26 and from 1.0 to 1.42 (per 1000) accordingly, especially in the youngest age group (0–6 years old) [Figs 1 and 2].

Conclusion: In recent years incidence rate of childhood DM1 continues to rise, especially in children aged 0–6 years old (vs 15–17 years old) on a background of decreasing of the total child population. The annual increase of incidence of DM1 in 2012 was 2.98%.

Figure 1 Incidence of DM1 in different age groups (per 1000 population).

Figure 2 Prevalence of DM1 in different age groups (per 1000 population).

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