Background and aim: Childhood obesity is one of the most serious public health problem. Obesity-related complications such as hepatic steatosis or type 2 diabetes can now be monitored even during early childhood. The aim of the study was to examine the relationship between vitamin D levels and obesity with hepatosteatosis (HS) in children.
Methods: A total of 128 children with obesity were included in this study. HS was diagnosed using ultrasonography. HS was graded. 25-hydroxyvitamin D, calsium, phoshate alkaline phosphatase, parathormone, serum lipid level, glucose and insuline level were measured. Data were analysed using two categories; obesity with HS and obesity without HS.
Results: A total of 128 children were studied. In our study group 42% was male and the mean age 12.1+3.1 (range 418 years) HS was identified in 39% (n: 50) There was a high prevalence (122/128 95%) of vitamin D deficiency or insufficiency; however, there were no significant associations between vitamin D level and HS. Uric acide, ALT, trigliseride level were significantly different in two groupes.
Conclusions: There is a high prevalence of vitamin D deficiency and insufficiency in children with HS however, no association was found between vitamin D deficiency and HS.
01 - 03 Oct 2015
European Society for Paediatric Endocrinology