ESPE Abstracts (2021) 94 P2-210

1Clínica Universidad de Navarra, Pampona, Spain; 2University of Navarra, Pamplona, Spain; 3Institue of Research of Navarra, Pamplona, Spain; 4Clínica Universidad de Navarra, Pamplona, Spain; 5Complejo Hospitalario de Navarra, Pamplona, Spain; 6Institute of Research of Navarra, Pamplona, Spain


Aim: to evaluate sleep quality by accelerometry and its association with anthropometry and biochemical parameters in children and adolescents after a multidisciplinary intervention

Subjects Materials and Methods: One hundred and twenty-two children and adolescents with abdominal obesity, aged 7 to 16 years, were included in a multidisciplinary intervention study to lose weight. Abdominal obesity was diagnosed using the waist circumference (>p90). The intervention included an intensive phase during 2 months. Participants were divided in two groups: intervention and control. Intervention group was treated with hypocaloric Mediterranean diet and the control group with the standard recommendations from Community Nutrition Spanish Society, 2007. Both groups were advised to increase in 200 minutes per week their moderate-vigorous physical activity. Sleep was assessed by accelerometry (Actigraph GT3X) at the onset, after intensive phase, at 12 and 24 moths of follow-up. Sleep parameters analysed were: number of awakenings and sleep latency, total sleep time, time in bed, awakenings duration and wake after sleep onset (WASO). Anthropometric parameters measured were: weight, height, body mass index, waist, hip and neck circumferences, fat mass and fat-free mass. Biochemical parameters determined were: insulin, leptin, cholesterol and triglycerides. Statistical analysis was done using STATA 12.0.

Results: sleep parameters improved in both groups throughout the follow-up and the improvement was higher and statistically significant in the intervention group. We observed the following statistically significant associations: latency and efficiency, number of awakenings and awakenings duration, efficiency with all the sleep parameters, number of awakenings and efficiency, awakenings duration and WASO, time in bed and both total sleep time and WASO. At 2 years follow-up, we observed a higher reduction in both insulin and leptin and a higher significant improvement in all the anthropometric parameters in the intervention group. At 2 years follow-up, we observed the following statistically significant associations: triglycerides reduction and time in bed, fat mass decrease and number of awakenings reduction, awakenings duration reduction and LDL-cholesterol decrease, latency improvement and insulin reduction.

Coclusion: the significant anthropometric, biochemical and sleep parameters changes observed after intervention remain throughout the follow-up of the patients, and is accompanied by an improvement in their sleep quality, and a decrease in their cardiometabolic risk metabolic.

Volume 94

59th Annual ESPE (ESPE 2021 Online)

Online,
22 Sep 2021 - 26 Sep 2021

European Society for Paediatric Endocrinology 

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