ESPE Abstracts (2023) 97 P1-473

1University Pediatric Clinic, Skopje, Macedonia, the former Yugoslav Republic of. 2Department of Pediatric Endocrinology, Skopje, Macedonia, the former Yugoslav Republic of. 3Department of Pediatric Cardiology, Skopje, Macedonia, the former Yugoslav Republic of. 4Department of Pediatric Genetics, Skopje, Macedonia, the former Yugoslav Republic of. 5Department of Pediatric endocrinology, Skopje, Macedonia, the former Yugoslav Republic of. 6Department of Pediatric Gastroenterohepatology, Skopje, Macedonia, the former Yugoslav Republic of. 7Department of Pediatric Hematology, Skopje, Macedonia, the former Yugoslav Republic of. 8University Pediatric clinic, Skopje, Macedonia, the former Yugoslav Republic of


Introduction: Obesity in children and adolescents is increasing, and represents a global concern regarding future health related consequences. It has been classified as a disease that affects a large number of individuals.

Materials and Methods: We have recruited 119 obese children and adolescents from our outpatient Pediatric Endocrine Clinic for metabolic evaluation between the year 2018-2022. There was a 2year discontinuation of the study period due to Covid-19 pandemic. Physical examination was performed along with measurement of arterial blood pressure, weight and height with body mass index (BMI) calculation. Blood samples were collected for cholesterol, lipoproteins, triglycerids, insulin and thyroid function. An OGTT was performed for each patient.

Preliminary Results: The mean age of patients was 11,2 years, with mean BMI of 31,7. Hypertension was found in 36 children (30%), mean age 12,6 years (BMI 34,4), dyslipidemia in 34 children (28,5%) BMI 32, mean age 11 years, subclinical hypothyroidism in 27 (22,6%), with a mean age of 10,4 years and BMI of 33,2. Hyperinsulinaemia in 46 children (38,6%) and mean age of 10,9 years BMI 32,3. Impaired glucose tolerance was found in 9 children (7,5%) with a BMI of 32, prediabetes in 1(0,8%) and diabetes type 2 in 4 (3,3%) patients. Metabolic syndrome had 2 patients, 1,6% age 13 and 14 years, BMI 36 and 34. Only 11 subjects (7,4%) were metabolically healthy, mean age 10,6 years and BMI 31,4.

Conclusion: Our results raise concern regarding the long term outcome of examined subjects. Only 7,4% of the patients were metabolically healthy. Before this time period, type 2 diabetes was not diagnosed in children. The growing incidence of obesity in our country requires the need for medical intervention, multidisciplinary approach and wide spread preventive education.

Volume 97

61st Annual ESPE (ESPE 2023)

The Hague, Netherlands
21 Sep 2023 - 23 Sep 2023

European Society for Paediatric Endocrinology 

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