ESPE Abstracts

Papillary cancer represents majority of thyroid malignancies in children. However prognosis remains very successful. In recent years, we use elastography, except biopsy and standard ultrasonography in thyroid lesions diagnostic. We present a case of a male patient at the age of 13 years, with a history of ADHD and school phobia who was referred to Endocrinology Outpatient Clinic due to partial empty sella syndrome. Family history of endocrinological disorders was negative. Ph...

At present no European recommendations for the management of pediatric thyroid nodules and differentiated thyroid carcinoma (DTC) exist. Differences in clinical, molecular, and pathological characteristics between pediatric and adult DTC emphasize the need for specific recommendations for the pediatric population. An expert panel was instituted by the executive committee of the European Thyroid Association (ETA) including an international community of experts from a variety of...

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder of the young women, and it could influence both physical and psychological wellbeing. As a consequence of obesity and hirsutism lower sexual attractiveness, higher emotional distress as well as higher depression score is frequently observed.Study Objective was to evaluate anxiety and depression score as well as the body esteem and stress perception ...

Background: Chemerin is an adipocytokine which plays a great role in metabolism of carbohydrates. Chemerin concentration correlates positively with body mass (BM). GH deficiency (GHD) is associated with excess of abdominal fat tissue also in patients with normal BMI.Objective and hypotheses: To estimate the chemerin concentration and its correlation with BM and carbohydrate metabolism in non-obese, prepubertal children with isolated GHD before (GHD untre...

Background: GH deficiency (GHD) is usually associated with excess of abdominal fat tissue and increased risk of developing cardiovascular diseases. Adipose tissue produces different adipocytokines that could explain the relationship between excess of fat tissue and increased metabolic risk. Adipsin, omentin and vaspin are adipocytokines which are still not well examined.Objective and hypotheses: To estimate the effect of 6 months GH therapy on serum conc...

Background: Both, obesity and hyperandrogenism are the conditions that can influence many different health domains, also may affect the mental and social wellbeing components of subject’s life.Study objective: To evaluate whether body weight status and clinical hyperandrogenism may influence social competencies and psychological gender features in adolescent girls.Design & participants: In 104 adolescent girls clinical eva...

Introduction: Graves'disease (GD) is a polygenic and multifactorial disease.The innate immune system is a complex network of structured cells and proteins, including the Toll-like receptors (TLRs), which are also expressed on the cells of the adaptive immune system.The aim was to assess the relationship between the expression of TLR-2 on the surface of T CD4+ and CD8+ lymphocytes in pat...

Introduction: Diabetes type 1 (DM1) in children can result in lipid disorders due to insulin deficiency. Familial hypercholesterolaemia (FH) is a very common monogenic disorder with occurrence of 1:250 and it may lead to development of cardiovascular disease (CAD) in a very young age.Case report: Female patient with diabetes diagnosed at the age of 5, was referred to joint diabetes and lipid clinic due to high levels of ...

Background: It is observed from nearly 50 years that the incidence of diabetes worldwide is increasing. Also the incidence of type 1 diabetes, which is most common in paediatric population, rises across Europe.Objective and hypotheses: The aim of the study was to analyze the incidence of type 1 diabetes in Poland in Pomeranian province in the years 2005, 2010 and 2015. The hypothesis was an increased incidence of type 1 diabetes.Me...

Background: Fibroblast growth factor 21 (FGF21) is a metabolic and growth regulator. The growth-promoting effect of GH in children with GH deficiency (GHD) depends on many factors. FGF21 concentration in and its interaction with growth deficiency and growth response to GH therapy in GHD was not examined.Objective and hypotheses: To estimate the FGF21 concentration and its correlation with degree of growth deficiency and growth response in non-obese, prep...