hrp0098p3-319 | Late Breaking | ESPE2024

Relevance of the hypoglycemic insulin stimulation test in 486 cases

Salih Bendeddouche Ahmed , Chemlal Soundous , Dali Youcef Meryem , Bouriche Khadidja , Senouci Djawida , Mazari Wafa , Benasla Djihane , Benchikh Sana , Rafii Bouheraoua Mohamed , Hamidi Wahiba , Boukli-Hacene Chakib , Belgherbi Chahrazed , Kadouci Hanane , Ouahiani Raouida , Bezzaouya Hadjer , Hamini Rahma , Belbachir H.L

Objective: Determine the relevance of the hypoglycemic insulin stimulation test for GH secretion in the context of the exploration of stature delay in childrenMaterials and Methods: This is a prospective study carried out during the year 2022, of 486 children followed for the management of failure to thrive in the pediatric department of CHU Tlemcen.Inclusion criteria: SR or slowin...

hrp0084p3-1005 | Gonads | ESPE2015

Incidence and Etiology of Hyperandrogenism in Children and Adolescent

Mahdi Haddam Ali El , Hafsa Si Youcef , Radhia Si Youcef , Djamila Meskine

Background: The hyperandrogenism in the teenager is a frequent reason for consultation. It poses diagnostic problems and sometimes therapeutic ones.Objective and hypotheses: Search of the incidence and aetiology of hyperandrogenism in children and adolescent.Method: This is a retrospective study of patients hospitalized for exploration of hyperandrogenism. 14 patients was for collected, all underwent to a profound clinical examinat...

hrp0089p3-p329 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P3 | ESPE2018

About a Case of Leydig Cell Tumor Associated with Central Precocious Puberty

Meryem Bensalah , Yamina Aribi , Houda Badrane Nour El , Samia Ouldkablia

Background: Leydig cell tumor (LCT) is a rare testicular tumor developing from male gonadal interstitium and most common type of testicular sex cord-stromal tumor. Its incidence is about 1%–3% of all testicular neoplasms. In children only few cases had been reported and are associated with pseudo puberty.Case report: We report a case of a 4 years old boy admitted to our unit for management of precocious puberty which started one year ago with increa...

hrp0084p3-656 | Bone | ESPE2015

Retrospective Evaluation of Patients Diagnosed as Nutritional Rickets: A Single Centre Study

Karaca Meryem , Cetinkaya Semra Caglar , Keskin Meliksah , Aycan Zehra

Background: Nutritional rickets continues to be an important health care problem. Its incidence has decreased in our country following the free vitamin D distribution that started in 2005 but it continues to stay on the agenda as a preventable disorder.Aim: Our aim was to evaluate patients diagnosed with nutritional rickets following the vitamin D supplementation program.Method: We evaluated patients diagnosed with nutritional rick...

hrp0098p3-274 | Late Breaking | ESPE2024

Iatrogenic cushing's syndrome in infants: Clinical and evolutionary aspects

Smouni Meryem , Amhajar Samah , Filali Imane , Imane Zineb

Introduction: Cushing's syndrome is a rare but serious condition in children. It is most often of iatrogenic origin, resulting from the prolonged use of glucocorticoids. It is responsible for increased cardiovascular mortality, highlighting the importance of recognizing and treating it. Cushing's syndrome due to topical application is a very rare cause, with only a few cases reported in the literature. We present here three cases of iatrogenic Cushin...

hrp0098p3-340 | Late Breaking | ESPE2024

Pituitary stalk interruption syndrome: Clinical, biological and radiological aspects of 20 cases.

Smouni Meryem , Filali Imane , Amhajar Samah , Imane Zineb

Introduction: Pituitary stalk interruption syndrome (PSIS) is a relatively common cause of growth hormone deficiency and hypopituitarism, often diagnosed during the neonatal period or early childhood. Is a syndrome characterized by an absent or hypoplastic anterior pituitary gland, thin or absent infundibulum, and ectopic posterior pituitary location. The aimof this study is to describe the clinical and paraclinical aspects of PSIS.<stro...

hrp0089p2-p188 | Fetal, Neonatal Endocrinology and Metabolism P2 | ESPE2018

Diazoxide Unresponsive Congenital Hyperinsulinism due to a Novel ABCC8 Missense Mutation

Ouarezki Yasmine , Ladjouze Asmahane , Djermane Adel , Houghton Jayne , Maouche Hachemi , Bouzerar Zohir , Tayebi Youcef

Background: Congenital hyperinsulinism is a frequent cause of persistent hypoglycaemia in neonates. Mutations of the KATP channel subunit are the most common molecular defects. We report here a novel ABCC8 gene mutation causing a severe form of CHI in a newborn.Case report: A 10-day-old boy born to consanguineous parents was referred for persistent hypoglycaemia. He was born by normal vaginal delivery at 38 weeks gestation, birth weight was 4....

hrp0082p3-d3-808 | Gonads and Gynaecology | ESPE2014

Phenotypic and Genotypic Characteristics of Patients with Turner Syndrome

Fedala Soumeya , Haddam Mahdi , Chentli Farida , Meskine Djamila , Akkache Lyna , Youcef Hafsa Si

Background: Turner syndrome (TS) is the most common chromosomal abnormality in females (prevalence 1/2500 births). It is related to the absence or abnormality of one of the two X chromosomes. It is characterized by a short stature, gonadal failure and a many diseases that reduce life expectancy of patients.Objective and hypotheses: Report Clinical, hormonal, Cytogenetics and evolutionary ST characteristics then correlate the karyotype and clinical expres...

hrp0092p3-113 | Fat, Metabolism and Obesity | ESPE2019

Severe Hypernatremia Revealing A Rohhad-Net Syndrome

Ouarezki MEDICAL/HEALTH , Bouferoua Fadila , Djermane Adel , Boucenna Hamza , Boukhedouma Nabila , El-Mokhtar Mohamed , Maouche Hachemi , Benhalla Nafissa , Tayebi Youcef

Introduction: Rapid-onset Obesity with Hypoventilation, Hypothalamic dysfunction and Autonomic Dysregulation (ROHHAD) recently named ROHHAD-NeuroEndocrine Tumors (ROHHAD-NET) syndrome is a rare cause of obesity in children. The diagnosis is challenging and can easily be confused with other causes of obesity.Case Report: We report a case of a six-year-old boy, referred to our clinic for hypernatremia. Six months ago, he s...

hrp0094p2-47 | Adrenals and HPA Axis | ESPE2021

Clinical, biological and genetic aspects of congenital adrenal hyperplasia in children at the Central Army Hospital in Algiers

Iabbassen Malek , Bensalah Meryem , Tardy-Guidollet Veronique , Menassa Rita , Morel Yves , Ouldkablia Samia Khadidja ,

Context: Congenital adrenal hyperplasia (CAH) is a rare genetic defect. Its prevalence is estimated at one case per 3,000 births in Algeria and one case per 15,000 births worldwide. The most common form is due to 21-hydroxylase deficiency associated with mutations in the 21-hydroxylase gene, which is located at chromosome 6p21. Molecular defects of CYP21A2 systematically decrease the activity of this enzyme and result in expression of varying severity and phen...