hrp0098p1-21 | Diabetes and Insulin 1 | ESPE2024

A population preventive study of early detection of type 1 diabetes in asymptomatic children in the North-East region of Poland

Bossowski Artur , Noiszewska Klaudyna , Jamiołkowska-Sztabkowska Milena , Zasim Aneta , Polkowska Agnieszka , Bossowski Filip , Skorupska Magdalena , Buczyńska Angelika , Krętowski Adam , Sikora Tobiasz , Trzonkowski Piotr

Introduction: The population study of early detection of type 1 diabetes (T1D) in asymptomatic children in the Podlaskie region of Poland is an extension of the Pre-d1abetes Study conducted by our clinic between 2019 and 2023 in collaboration with 14 Polish diabetes centres. A total of 1288 patients aged between 7 months and 18 years were studied with positive family of T1D. Positive 3-screen ELISA values were observed in 112 patients (8.69%). During analysis ...

hrp0082p1-d1-208 | Reproduction | ESPE2014

GH Therapy in Turner Syndrome Patients: the Effects on Nutritional Status, Adipokines, and Aortic Dilatation

Magnuszewska Hanna , Gnacinska-Szymanska Maria , Wisniewski Piotr , Potaz Piotr , Birkholz-Walerzak Dorota , Korpal-Szczyrska Maria , Sworczak Krzysztof

Background: Turner syndrome (TS) patients are at increased obesity risk. Additionally body composition in TS is distinctly altered. The percentage of body fat mass (BFM) is higher. Also adipokine dysregulation is observed. TS is associated with aortic dilatation, which is seen not only in patients with congenital aortic defects but also in patients without underlying pathology. Considering different co-morbidities common in TS, it’s extremely important to evaluate wide sp...

hrp0092p1-287 | Thyroid (1) | ESPE2019

The Comparison of Natural Course Thyroid Autoimmunity in Children and Adults with Type 1 Diabetes: From the Diabetes Onset Up to Five Years of its Duration

Niechcial Elzbieta , Frontczak Anita Rogowicz- , Pilacinski Stanislaw , Fichna Piotr , Zozulinska-Ziólkiewicz Dorota

Introduction: Individuals with type 1 diabetes (T1D) are at higher risk of developing other autoimmune disease, including autoimmune thyroid diseases (AITD). The incidence of Hashimoto among people with T1D varies between 8 and 50%, depending on gender, age and ethnicity.Aim: To evaluate prevalence of anti-thyroid peroxidase (anti-TPO) and its correlation to the presence of thyroid dysfunction in children and adults ...

hrp0089p3-p045 | Bone, Growth Plate & Mineral Metabolism P3 | ESPE2018

Idiopathic Hypoparathyroidism in a 10 Year-Old Girl with Concomitant Epilepsy, Long Q-T Syndrome (LQTS), Pericarditis and Pneumonia

Borysewicz-Sańczyk Hanna , Sawicka Beata , Kiryluk Barbara , Szumowski Piotr , Allgrove Dr. Jeremy , Bossowski Artur

Introduction: PTH is one of the principal regulatory hormones for calcium and phosphate homeostasis. Hypoparathyroidism, caused by reduced parathyroid hormone (PTH) concentration is characterised by hypocalcemia and hyperphosphataemia. Hypoparathyroidism in children can occur either as part of a genetic syndrome, autoimmune disorder, be acquired secondarily to thyroidectomy or some destructive process of the glands. If the reason for decreased PTH concentration is unknown, it ...

hrp0086p1-p237 | Diabetes P1 | ESPE2016

The Prevalence of Diabetic Ketoacidosis in Children with New-Onset Type 1 Diabetes Mellitus

Niechcial Elzbieta , Gertig-Kolasa Anna , Krzysko-Pieczka Izabela , Skowronska Bogda , Stankiewicz Witold , Michalak Michal , Fichna Piotr

Background: Children at type 1 diabetes (T1DM) diagnosis can develop ketoacidosis (DKA), a life-threatening condition, which is most frequently associated with the onset of diabetes in children aged <5 years.Aims and objectives: We studied the prevalence of DKA at T1DM diagnosis and the frequency of partial remission (PR) in children from Wielkopolska province, Poland.Method: The cohort comprised 735 children aged 0–18 yea...

hrp0084p3-632 | Autoimmune | ESPE2015

Thyroid Function and Autoimmunity in Children with Newly Diagnosed Type 1 Diabetes Mellitus

Niechcial Elzbieta , Skowronska Bogda , Gertig-Kolasa Anna , Krzysko Izabela , Stankiewicz Witold , Michalak Michal , Fichna Piotr

Background: Patients with type 1 diabetes (T1DM) are at a high risk of having other autoimmunological diseases. The most common coexisting disease is autoimmune thyroiditis, which is diagnosed in 15–30% diabetic patients. The incidence of the disease depends on the age, sex, and duration of T1DM.Aims and objectives: This study aims to assess the prevalence of anti-thyroid peroxidase antibodies and anti-thyroglobulin antibodies in children with newly...

hrp0086p1-p234 | Diabetes P1 | ESPE2016

Assessment of Selected Carbohydrate Parameters in Children Exposed to Gestational Diabetes in utero

Wilk Malgorzata , Horodnicka-Jozwa Anita , Moleda Piotr , Petriczko Elzbieta , Safranow Krzysztof , Chojnacka Hanna , Gawrych Elzbieta , Walczak Alicja , Walczak Mieczyslaw

Background: Children exposed to gestational diabetes mellitus (GDM) in utero have higher risk of development of glucose intolerance and diabetes mellitus.Objective and hypotheses: The study was undertaken to assess the selected carbohydrate parameters in children exposed to gestational diabetes in utero.Method: 50 children exposed to gestational diabetes were compared with 46 control subjects. Anthropometric parameters of a newborn...

hrp0086p1-p475 | Fat Metabolism and Obesity P1 | ESPE2016

Reduction of Body Mass and Change in Body Composition of the Participants of the PoZdro! – Programme for Prevention of Diabetes and Civilisation Diseases by Medicover Foundation – Preliminary Results, after the First Year of Interventions

Magnuszewska Hanna , Anyszek Tomasz , Brzezinski Michal , Lech Monika , Soszynski Piotr , Walewski Jacek , Szarejko Kamila , Radziwill Marcin , Mysliwiec Malgorzata , Czupryniak Leszek

Background: Lifestyle interventions are basic tool to treat obesity in the youth. They prevent from civilisation diseases. Globally, there are many programmes including regular meetings with dieticians, exercise specialists, and others. Results are promising, although there’s no consensus regarding one model of recommended diet, exercise’s intensity and frequency of interventions.Objective and hypotheses: Assessment of preliminary results of &#...

hrp0082p1-d3-191 | Pituitary | ESPE2014

Phenotype Evaluation of Combined Pituitary Hormone Deficiency Caused By prop1 Gene Mutation in Comparison to Pituitary Deficiency Caused by Other Factors

Zygmunt-Gorska Agata , Starzyk Jerzy , Wojcik Malgorzata , Madetko-Talowska Ewa , Sucharski Piotr , Herman-Sucharska Izabela , Pietrzyk Jacek J

Background: Combine pituitary hormone deficiency (CPHD) may be caused by many factors. One – them is PROP1 gene mutation, that causes maldevelopment of GH, TSH, LH, FSH prolactin but not ACTH, producing cells (CPHD–PROP1).Objective and hypotheses: The details of possible differences between phenotypes of CPHD–PROP1 and CPHD of other reasons (CPHD–nonPROP1) are not clear to date. The aim of the study...

hrp0086p1-p464 | Fat Metabolism and Obesity P1 | ESPE2016

Central Obesity among European Preschool Children: The ToyBox-Study

Galcheva Sonya , Lateva Mina , Iotova Violeta , Androutsos Odysseas , Manios Yannis , De Bourdeaudhuij Ilse , Cardon Greet , Socha Piotr , Moreno Luis , Koletzko Berthold , on behalf of ToyBox-Study Group

Background: Waist circumference (WC) reflects the fat distribution and the degree of central adiposity in children, which is specifically associated with cardiovascular risk factors and useful as a component of metabolic syndrome definition in children.Objective and hypotheses: To evaluate the distribution of WC measures among preschool children aged 3.5–5.5 years from six European countries.Method: Cross-sectional study of a ...