ESPE Abstracts

Background: Treatment of childhood and adolescent obesity is rarely effective if “cure” i.e., BMI below the obesity range, is used as the definition of success. However, results of obesity treatment is much more effective if treatment is initiated in 6–7 years old children. It is therefore urgent to develop interventions for young children, both preventive and obesity treatment efforts. Results from such interventions as well as preliminary results from ongoing ...

Background: Severe GH deficiency (GHD) leads to several metabolic effects in the body ranging from abnormal body composition to biochemical disturbances such as high insulin sensitivity. However, less is known regarding these parameters in children with a milder deficiency in GH secretion.Objective and hypotheses: To analyse if short children with a relatively low GH secretion differ metabolically from healthy children of normal height.<p class="abst...

Objective: Growth hormone (GH) is a central hormone for regulating linear growth during childhood and also highly involved in metabolism of lipids, carbohydrates and protein. However, few studies report on how treatment with GH during childhood influences metabolic parameters. Our aim was to investigate metabolic effects of different doses of GH in short children with GH peak levels in the low normal range.Design: Thirty...

Background: The integration of mobile health technology with a limited number of physical visits shows promising treatment outcomes, but long-term evidence is lacking. Additionally, concerns about eating disorders following obesity treatment are common among families and caregivers, although data on this matter are scarce for children and adolescents. This study evaluates three-year weight outcomes for patients using a digi-physical treatment tool and reviews ...

Introduction: The substantial increase in prevalence of childhood obesity presents a major challenge. Obesity is associated with significant physical and mental co-morbidities including diabetes and cardiovascular disease. Successful treatment requires intensive input from a specialist multidisciplinary team. In 2019, NHS England initiated a pilot to treat Complications Relating to Excess Weight (CEW) in dedicated clinics across the country. Facilitating suffi...

Background: Screening for autoimmune thyroid disease in children and adolescents with type 1 diabetes lacks consensus. Optimal screening methods should benefit the patients and reduce costs to healthcare.Objective and hypotheses: To, at diagnosis of type 1 diabetes, determine the predictive value of thyroid autoantibodies, thyroid function, islet autoantibodies, and HLA-DQ for autoimmune thyroid disease.Method: At diagnosis of type...

Obesity remains a critical global health concern. Traditional treatment often yields limited results, necessitating innovative solutions. The Evira tool; comprising a digitless scale and a mobile application with real-time feedback, addresses these challenges by enhancing home- based monitoring. The primary aimwas to evaluate its efficacy for childhood obesity treatment in Abu Dhabi, with a secondary objective to establish non-inferiority compared to outcomes in Stockholm, Swe...