hrp0084p3-745 | Diabetes | ESPE2015

Vitamin D Status in Egyptian Children with T1D and the Role of Vitamin D Replacement on Glycaemic Control

Hafez Mona , Hassan Mona , Sharaf Sahar , Musa Noha , Sameh Sally

Background: Many epidemiological studies have found high prevalence of vitamin D deficiency in children with type 1-diabetes mellitus (T1D). 1,25(OH)2D is a potent immune-modulator that also enhances the production and secretion of several hormones, including insulin. The association of low serum 1,25(OH)2D levels with high glucose level and diminished insulin sensitivity suggests that vitamin D may modulate insulin metabolism.Aim and objectives: To scre...

hrp0084p3-856 | Fat | ESPE2015

Relationship between Visceral Obesity and Plasma Fibrinogen in Obese Children

Hafez Mona , Masry Sahar El , Musa Noha , Fathy Marwa , Hassan Mona , Hassan Nayera , Tareef Mahmoud , Husseiny Mohamed El

Background: The prevalence of obesity in children and adolescents has increased significantly worldwide with an alarming rise of its co-morbidities. The excess of visceral adipose tissue is associated with hypertension, prothrombotic and pro-inflammatory states leading to cardiovascular diseases.Aim of the study: To find possible associations between visceral obesity and plasma fibrinogen, as one of the cardiovascular risk factors, in obese children....

hrp0092lb-17 | Late Breaking Posters | ESPE2019

Assessment of Urinary Podocalyxin as a Marker of Glomerular Injury in Obesity Related Kidney Disease in Obese Children and Adolescents compared to urinary Albumin-creatinine ratio

Hassan Mona , Musa Noha , Ramzy Tarek , Hamdy Ahmed

Introduction: Epidemiological data suggest that obesity was associated with increased risk of renal injury in children.Objective: To assess urinary podocalyxin in obese children and adolescents as a marker of obesity related kidney disease (ORKD) compared to urinary albumin creatinine (A/C) ratio as the standard marker of glomerular injury.Methodology: This case-control study inclu...

hrp0086p2-p310 | Diabetes P2 | ESPE2016

Diabetic Ketoacidosis: Clinical Features and Precipitating Factors at DEMPU

Ibrahim Amany , Hassan Mona Mamdouh , Arafa Noha , Eldin Asmaa Salah

Background: Diabetic ketoacidosis (DKA) is an acute complication of type 1 diabetes mellitus (T1DM) that can be fatal if not properly managed. DKA is a leading cause of mortality in these children, early recognition and prompt treatment should substantially reduce childhood mortality in children with T1DM.Objective and hypotheses: We aimed to identify the risk factors and the most common clinical features of newly diagnosed diabetes in children, in addit...

hrp0084p3-739 | Diabetes | ESPE2015

Assessment of Quality of Life in Adolescents with Type 1 Diabetes; a Pilot Study

Hassan Mona , Musa Noha , Hay Rehab Abdel , Fathy Ashgan

Background: Diabetes as a disease and its treatment can have a profound effect on the quality of life (QoL) in terms of social and psychological well-being as well as physical ill health. Current goals of diabetes management focus on optimising metabolic control, along with preserving a good QoL.Aims and objectives: To assess QoL in adolescents with type 1 diabetes (T1D) at the Diabetes Endocrine and Metabolism Pediatric Unit at Cairo University.<p c...

hrp0095p2-156 | GH and IGFs | ESPE2022

Short Term Effects of Growth Hormone in Children and Adolescents with Growth Hormone Deficiency

Tawfik Sameh , Hassan Mona , Attia Mona , Atef Abeer , Mira Marwa , Dowidar Wafaa , Elkhashab Khaled , Diab Wala

Introduction: Children with Growth Hormone deficiency(GHD) should be treated with r-hGH as early as possible after the diagnosis is made. The primary objectives of therapy is to normalize growth during childhood and to achieve final height within their genetic potential.Objectives: To determine impact of GH treatment on short term linear growth in the 1st year of therapy in children with isolated growth hormone deficienc...

hrp0089p2-p031 | Adrenals and HPA Axis P2 | ESPE2018

The Relationship Between Vitamin D Status and Metabolic Abnormalities in Females with Classical Congenital Adrenal Hyperplasia: A Pilot Study

Hassan Mona , Ibrahim Amany , Abdou Marise , Atty Sahar Abdel , Nabil Diana

Congenital adrenal hyperplasia (CAH) patients have a higher frequency of obesity, visceral adiposity, hyperinsulinism, insulin resistance and hyperandrogenism. There is increasing evidence that low vitamin D status is associated with impaired β-cell function, insulin resistance and impaired glucose tolerance.Objectives: This pilot aimed to determine the status of serum 25 (OH) D levels in CAH female patients who are followed up in Diabetes Endocrine...

hrp0086p1-p235 | Diabetes P1 | ESPE2016

The Genetic Causes and Phenotypic Characteristics of Egyptian Patients with Neonatal Diabetes Mellitus

Elkaffas Rasha , Musa Noha , Franco Elisa De , Madani Hanan A , Shaalan Yomna , El-Kaffas Rania M.H. , Hassan Mona , Hafez Mona , Kholi Badawy El , Flanagan Sarah E , Ellard Sian , Hussain Khalid

Background: Neonatal Diabetes Mellitus (NDM) is a rare form of monogenic diabetes that typically presents during the first 6 months of life. Its prevalence is about 1:100 000 live births; however it may rise up to 1:29 000 in highly consanguineous populations. Mutations in 22 different genes are reported; with the most common cause being potassium channel subunit gene (KCNJ11/ABCC8) mutations. However, causative mutations among consanguineous populations seem to diffe...