hrp0094p2-465 | Thyroid | ESPE2021

Allan-Herndon-Dudley syndrome: case report of a rare disorder

Navasardyan Lusine , Muradyan Irina

Introduction: Allan-Herndon-Dudley syndrome (AHDS) is an X linked disorder – mutation of monocarboxylate transporter 8 (MCT8) gene. It leads to a severe psychomotor retardation, significant hypotonia of the skeletal muscles, spastic or dystonic quadriplegia. MCT-8 is responsible for the uptake of T3 by neurons of CNS. AHDS is characterized by increased T3 concentration, increased T3 / T4 ratio, TSH not depressed, even slightly elevated levels. Because of impossibility f...

hrp0097p2-187 | Adrenals and HPA Axis | ESPE2023

Challenges and barriers of choosing the sex in patients with congenital adrenal hyperplasia: a case report

Navasardyan Lusine , Tumasyan Dalar , Muradyan Irina , Marutyan Irina , Sarinyan Sofi

Background: Congenital adrenal hyperplasia (CAH) is a disorder, leading to hyperandrogenaemia in the period of organogenesis of external genitalia, resulting in the disorders of sex development(DSD) in 46XX patients where external and internal genitalia do not correspond to each other. The aim of current work is to show the barriers and challenges in a 46XX patient in choosing the sex for up-bringing the child.Case presentation:<...

hrp0097p2-302 | Late Breaking | ESPE2023

ESPE School Sharing Knowledge for Saving Patients' Lives: Empowering Pediatric Endocrinologists in Armenia

Navasardyan Lusine , Lundberg Elena , Toumasyan Dalar , Muradyan Irina

Background: Practicing as a Pediatric Endocrinologist in Armenia means living in a middle- to low-income country with semi-closed borders associated with war and conflicts. There are therefore fewer opportunities to attend educational events or training at highly rated hospitals worldwide to improve knowledge and skills on pediatric endocrinology. In April 2023 the Endocrine Society of Pediatric Endocrinologists (ESPE) held the ESPE Caucasus & Central Asia...

hrp0095p1-243 | Diabetes and Insulin | ESPE2022

Did Covid-19 pandemic restrictions impact on diabetic care of children and adolescents in Armenia?

Muradyan Irina , Aghajanova Yelena , Janvelyan Tamara , Markosyan Renata , Bayburdyan Gayane , Kalantaryan Lusine , Arakelyan Lusine , Navasardyan Lusine

Background: Type 1 diabetes mellitus (T1DM) is an autoimmune disorder, which occurs mostly among children and adolescents. Armenia is a middle-low income country, where pediatric diabetic care is given centralized in three main centers. The 85-90% of diabetic children and adolescents are followed in the university hospital. During Covid-19 pandemic Armenia was under either lockdown or strict restrictions. The purpose of the current study is to assess the dynam...

hrp0097p2-163 | GH and IGFs | ESPE2023

Taller in One Year: Early Intervention Emphasize of Growth Hormone Therapy in Children with Growth Hormone Deficiency

Muradyan Irina , Tumasyan Dalar , Manvelyan Diana , Harutyunyan Nora , Aghajanova Elena , Navasardyan Lusine

Background: Growth hormone deficiency (GHD) is a disorder affecting children's linear growth and leading to short stature without initiation of treatment with growth hormone (GH). Administration of GH has been shown to be safe and effective to increase children's final height in GHD. It is important to start the treatment as early as the GHD is diagnosed. The objective of the current study is to evaluate the growth velocity and height standard deviat...