hrp0082p2-d3-407 | Fat Metabolism & Obesity (2) | ESPE2014

Examining β-Cell Reserve in Extremely Obese Children

Neshkinska Maria , Galcheva Sonya , Lateva Mina , Iotova Violeta

Background: Obesity is a major risk factor for developing type 2 diabetes mellitus (T2DM). Despite the obesity epidemics, the incidence of childhood T2DM is not increased.Objective and hypotheses: To assess the β-cell reserve expressed as an oral glucose disposition index (GDIo), an independent predictor of developing T2DM.Method: A total of 80 adolescents (61.3% girls), aged from 10.0 to 17.6 years (mean age 13.59±2.34 y...

hrp0084p3-871 | Fat | ESPE2015

Body Composition and Metabolic Risk Factors in Preschool Children

Lateva Mina , Popova Ralitsa , Galcheva Sonya , Georgieva Miglena , Iotova Violeta

Background: Recently childhood obesity shows trends of lowering age at start. Preschool children are still very physically active. A possible association between total and abdominal obesity and metabolic risk at preschool age could be of value for preventive measures.Objective and hypotheses: To investigate the relationship between body composition and some metabolic risk factors at preschool age.Method: A total of 40 (50% boys) he...

hrp0086p2-p505 | Fat Metabolism and Obesity P2 | ESPE2016

Irisin and Abdominal Obesity in Preschool Age

Lateva Mina , Popova Ralitsa , Bocheva Yana , Galcheva Sonya , Chervenkov Trifon , Iotova Violeta

Background: Since its discovery in 2012 the ‘browining’ adipokine irisin is known to lead to increased thermogenesis and energy expenditure. Studies in children are scarce, with results similar to most studies in adults.Objective and hypotheses: To establish a link between total and abdominal fat mass, physical activity and irisin in preschool age.Method: Height, weight and waist circumference (WC) of 40 healthy pre-puber...

hrp0082p2-d1-370 | Fat Metabolism & Obesity | ESPE2014

Childhood Obesity, Renal Injury, and Future Disease Risk

Lateva Mina , Bliznakova Dimitrichka , Galcheva Sonya , Neshkinska Maria , Mladenov Vilhelm , Boyadzhiev Veselin , Halvadzhiyan Irina , Yordanova Galina , Iotova Violeta

Background: Evidence associates obesity with glomerular hyperperfusion. Concurrent inflammation, hypertension, dyslipidemia, and insulin resistance represent further established risks to renal health in both children and adults.Objective and hypotheses: To investigate the relationship between childhood obesity and risk of renal impairment.Method: A total of 114 (38.6% boys) obese according to the IOTF reference but otherwise health...

hrp0084p2-476 | Growth | ESPE2015

One Year Screening Program for Stature Deviations – Strategy and Outcome

Yordanova Galina , Iotova Violeta , Lateva Mina , Galcheva Sonya , Stoycheva Rositsa , Mladenov Vilchelm , Boyadjiev Vesselin , Bazdarska Yulia , Ivanova Antonia

Background: Many children still miss the early recognition of their stature problems due to inefficient screening strategies.Objective and hypotheses: To assess stature deviations referral through recruiting general practitioners (GPs) and providing them with tools for easier anthropometric data assessment and enhanced access to the Paediatric Endocrinologist.Method: Thirty-one general practitioners with a total of 23 058 patients ...

hrp0086p1-p464 | Fat Metabolism and Obesity P1 | ESPE2016

Central Obesity among European Preschool Children: The ToyBox-Study

Galcheva Sonya , Lateva Mina , Iotova Violeta , Androutsos Odysseas , Manios Yannis , De Bourdeaudhuij Ilse , Cardon Greet , Socha Piotr , Moreno Luis , Koletzko Berthold , on behalf of ToyBox-Study Group

Background: Waist circumference (WC) reflects the fat distribution and the degree of central adiposity in children, which is specifically associated with cardiovascular risk factors and useful as a component of metabolic syndrome definition in children.Objective and hypotheses: To evaluate the distribution of WC measures among preschool children aged 3.5–5.5 years from six European countries.Method: Cross-sectional study of a ...

hrp0084p1-51 | Diabetes | ESPE2015

Distribution of Obesity Indices Among European Preschool Children and Associated Risk Factors: The ToyBox-Study

Galcheva Sonya , Lateva Mina , Iotova Violeta , Bourdeaudhuij Ilse De , Cardon Greet , Androutsos Odysseas , Kulaga Zbigniew , Socha Piotr , Moreno Luis , Koletzko Berthold , Manios Yannis , Group ToyBox-study

Background: Childhood obesity is a serious health problem, related to an increased risk of adult morbidity and mortality. Evidence indicates that central adiposity increases this risk to a higher degree compared to the general obesity indices.Objective and hypotheses: To evaluate the distribution of anthropometric obesity indices among preschool children aged 3.5–5.5 years, from six European countries, and to examine their associations with certain ...