hrp0092p1-180 | Diabetes and Insulin (1) | ESPE2019

Efficacy and Safety of Insulin Degludec as a Basal Insulin in Adolescents with Type 1 Diabetes During Ramadan Fasting: A Single Center Observational Study with Freestyle Libre Flash Glucose Monitoring System

Elbarbary Nancy

Background: Insulin degludec (IDeg) is an ultra-long-acting insulin, with flat time-action profile, having a lower risk of hypoglycemia. Many adolescents with type 1 diabetes, choose to observe Ramadan fasting for spiritual wellbeing despite different risks.Aim of study: To assess frequency, timing and severity of hypoglycemia of insulin IDeg as basal insulin in T1DM adolescence who are willing to fast. Other outcomes in...

hrp0082p1-d3-82 | Diabetes (2) | ESPE2014

Holding the Horses of Insulin Pump Infusion: Usage and Effectiveness of the Low Glucose Suspend Feature During Fasting in Ramadan Among Adolescents with Type 1 Diabetes Mellitus to Prevent Hypoglycemia

Elbarbary Nancy

Background and aim: Severe hypoglycemic episodes during the daytime of Ramadan fasting is the most feared complication. Sensor-augmented pump therapy with insulin in combination with automatic insulin shutoff (low glucose suspend (LGS)) can be used to reduce hypoglycemia. In a prospective observational study, we investigated the effect of the LGS algorithm on the frequency of hypoglycemia in adolescents with type 1 diabetes who wished to fast Ramadan 2013.<p class="abstext...

hrp0095fc8.1 | Diabetes and Insulin | ESPE2022

Clinical effectiveness of Liraglutide 3.0 mg for weight management as an adjuvant therapy in obese adolescents with type 1 diabetes: A single-center pilot study

Elbarbary Nancy

Background: Recent data from multiple international registries showed higher rates of overweight and obesity in adolescents with type 1 diabetes (T1DM) compared with their non-diabetic peers. Management of weight gain should be emphasized as obesity is a modifiable cardiovascular risk factor. Liraglutide is a glucagon like peptide&dash;1 receptor agonist approved for chronic weight management in adolescents with body weight above 60 kg and body mass index (BMI...

hrp0082p3-d2-746 | Diabetes (3) | ESPE2014

Current Status of Diabetes Management, Glycemic Control and Complications in Children and Adolescents with Diabetes: a Registry-Based Study in Egypt: Where Do We Stand Now? and Where Do We Go from Here?

Elbarbary Nancy , Elsamahy Mona , Elmorsi Hala

Background: Given that diabetes is an extremely common disorder in Egypt, the Diabetes Registry was designed by Pediatric Diabetes Clinic, Ain Shams University Hospital in the year 2010.Aim: Identify risk factors related to poor glycemic control and to provide data to health professionals for use in planning, evaluation, and optimizing diabetes care in those patients.Subjects and methods: The registry was designed to provide inform...

hrp0084p3-1066 | Hypo | ESPE2015

Congenital Hyperinsulinism in a Newborn with a Novel Paternally Inherited Heterozygous Mutation (p.E1517G) in the ABCC8 Gene

Elbarbary Nancy , Ellard Sian , Hussain Khalid

Background: Congenital hyperinsulinism (CHI), a clinically and genetically heterogeneous disease, is the most common cause of persistent hypoglycaemia in infancy.Case presentation: Here we describe an Egyptian male neonate first order of birth born to non-consanguineous healthy parents. At day 1 of age he presented with severe hypoglycemia and generalised seizures. At the time of hypoglycaemia (16 mg/dl) insulin and C-peptide levels were increased (insul...

hrp0095p1-244 | Diabetes and Insulin | ESPE2022

Glycemic Outcomes and Safety During the MiniMed™ 780G Advanced Hybrid Closed-Loop System in Egyptian Patients with Type 1 Diabetes

Elbarbary Nancy , Shaarawy Mohamed , Selim Esraa

Background: Advanced Hybrid Closed Loop (AHCL) system includes an algorithm that provides both automated basal rate and correction boluses to keep glycemic values in a target range. Patients are only required to estimate carbohydrate consumption for meal boluses.Objectives: To evaluate the real-world performance of the MiniMed TM 780G system in Egyptian patients with type 1 diabetes.Methods...

hrp0089p1-p045 | Diabetes &amp; Insulin P1 | ESPE2018

Management of Diabetes During Ramadan Fasting in Children and Adolescents: Survey of Physicians’ Perceptions and Practices in the Arab Society of Paediatric Endocrinology and Diabetes (ASPED) Countries

Elbarbary Nancy , Deeb Asma , Habeb Abdelhadi , Beshyah Salem A

Background: Many Muslim adolescents and children insist on fasting during the holy month of Ramadan. There are limited data on the patterns of diabetes management specifically about children and adolescents.Aim: To ascertain the knowledge, attitude, and practices to the management of diabetes during Ramadan fasting among physicians who look after children and adolescents living with diabetes in Arab countries.Methods: An electronic...

hrp0082p1-d2-78 | Diabetes (1) | ESPE2014

Hormonal and Lipid Profile in Correlation with Anthropometric Measurements Among Offspring of Diabetic Mothers

Elbarbary Nancy , AboElAsrar Mohammed , El-Hadidy Eman , Maghrabi Marwa

Objective: This study was designed primarily to estimate whether there is an association between neonatal anthropometric parameters on one hand and cord blood levels of insulin, leptin, IGF1 and lipid profile on the other hand in offspring of diabetic mothers.Method: A total of 60 full term infants of diabetic mothers and 40 healthy infants of non-diabetic women participated in the study. Detailed anthropometric assessment of the newborn, head circumfere...

hrp0089fc3.3 | Diabetes and Insulin 1 | ESPE2018

Pediatric Patients with Type 1 Diabetes and Abnormal Nerve Conduction Studies Demonstrate Higher Neopterin Levels: Potential Role as a Biochemical Marker for Peripheral Neuropathy

Elbarbary Nancy , Ismail Eman Abdel Rahman , El- Hilaly Rana Ahmed , Ahmed Fatma Salama

Background: Electrophysiological techniques allowed identification of sub-clinical pathological changes and early diagnosis of diabetic peripheral neuropathy (PN). Neopterin is a marker of inflammation and cellular immune response that is elevated in conditions of T-cell or macrophages activation. Diabetic peripheral neuropathy (PN) is associated with inflammatory/immune processes and therefore, we hypothesized that neopterin could be used as a marker of neuropathy in type 1 d...

hrp0089fc12.5 | Diabetes and Insulin 2 | ESPE2018

Effect of Homocysteine-Lowering Therapy on Diabetic Nephropathy in children and adolescents with Type 1 Diabetes

Elbarbary Nancy , Ismail Eman Abdel Rahman , Zaki Mamdouh Ahmed , Ibrahim Marwa Zaki , El-Hamamsy Manal

Background: Diabetic nephropathy (DN) is a major microvascular complica-tion of type 1 diabetes mellitus (T1DM). Homocysteine levels have been found elevated in T1DM patients with DN due to several causes, including dietary deficiencies of folic acid and B Vitamins. Hyperhomocysteinemia induces renal injury and is associated with increasing urinary albumin excretion in patients with diabetes. We therefore performed a randomized-controlled trial of oral supplem...