hrp0092p2-72 | Diabetes and Insulin | ESPE2019

Adropin, Afamin And Neudesin - Novel Biomarkers of Type 1 Diabetes Mellitus in Children

Noiszewska Klaudyna , Bossowski Artur

Introduction: The incidence of type 1 diabetes mellitus (DM I) is rising. Newly discovered peptides: adropin, afamin and neudesin may play a key role in the diagnostic process in the future. Most studies assessing the relationship of those peptides provide data obtained from studies conducted on animals, adults with type DM II and women with gestational DM. There are only few studies concerning these relationships in children.Aim of the ...

hrp0089p1-p132 | Fat, Metabolism and Obesity P1 | ESPE2018

Non-Invasive Measurements of Central Blood Pressure with Arterial Stiffness Indicators as a New Research Tool for Predicting Cardiovascular Risk in Children with Type 1 Diabetes Mellitus and Obesity

Noiszewska Klaudyna , Puchalski Mateusz , Skolimowska Anna , Bossowski Artur

Introduction: The main problem of contemporary diabetology is to prevent chronic complications of carbohydrate metabolism disorders according to DM1 and obesity (pre-disposing for DM2). The task is to find simple tools that allow rapid identification of vascular lesions and early treatment intervention.Aim of the study: The aim of the study was to evaluate parameters of CBP in patients with DM1 and obesityMaterials and methods: The...

hrp0084p1-164 | Miscelleaneous | ESPE2015

Practical Application of Elastography in the Diagnosis of Thyroid Nodules in Children

Borysewicz-Sanczyk Hanna , Sawicka Beata , Dzieciol Janusz , Drzewek Katarzyna , Oleksinska Magdalena , Noiszewska Klaudyna , Bossowski Artur

Background: Elastography is non-invasive ultrasound method of imaging based on estimation of mechanical properties (elasticity) of the tissue. Recent data has shown its ability to differentiate benign from malignant tumours. Decreased flexibility in comparison to around tissue is characteristic for malignant tissues, like most thyroid carcinoma (except follicular thyroid carcinoma). Analysis of the image gives the result presented as a ROI1/ROI2 index.Ob...

hrp0084p3-1247 | Programming & Misc. | ESPE2015

The Association between Selected Endocrinopathies and Central Arterial Pressure in Children and Adolescents

Noiszewska Klaudyna , Krentowska Anna , Skoneczny Anna , Mazur Agnieszka , Borysewicz-Sanczyk Hanna , Bossowski Artur

Background: Many endocrinopathies are associated with cardiovascular abnormalities. Central blood pressure (CAP), reflecting the condition of blood vessels, may be useful in monitoring of patients with endocrinopathies.Objective and hypotheses: To evaluate parameters of CAP in patients with selected endocrinopathies.Method: The study group comprised 122 patients (58 girls and 64 boys) with endocrinopathies: GH deficiency before GH ...

hrp0097rfc5.3 | Diabetes and insulin 1 | ESPE2023

3 Screen ICA ELISA–A new tool to identify pre-clinical diabetes in first-degree relatives of patients with type 1 diabetes (pre-d1abetes study)

Bossowski Artur , Noiszewska Klaudyna , Polkowska Agnieszka , Zasim Aneta , Jamiolkowska Milena , Mysliwiec Malgorzata , Szadkowska Agnieszka , Mazur Artur , Jarosz-Chobot Przemyslawa , Szypowska Agnieszka , Chobot Agata , Nazim Joanna , Zubkiewicz Agnieszka , Ben-Skowronek Iwona , Niechcial Elzbieta , Walczak Mieczyslaw , Jozwa Anita , Mincewicz-Wysocka Marta , Robak-Kotna Katarzyna , Chen Shu , Furmaniak Jadwiga , Smith Bernard

Introduction: Overt clinical symptoms of type 1 diabetes (T1D) are often preceded by a pre-clinical stage of varying duration. Diagnosis of the pre-clinical stage is difficult and is based on the presence of specific islet autoantibodies in the subject's blood. Objectives: Apparently healthy first-degree relatives of patients with T1D were tested using the 3 Screen ICAELISA (RSR Ltd) for combined testing for autoantibodies to GAD65 (glutamic acid decarbox...

hrp0095p1-241 | Diabetes and Insulin | ESPE2022

3 Screen ICA TM Elisa - A New Tool for Identify Pre-Clinical Diabetes in First-Degree Relatives of Patients with Type 1 Diabetes (Pre-D1Abetes Study)

Noiszewska Klaudyna , Bossowski Artur , Zasim Aneta , Jamiołkowska-Sztabkowska Milena , Polkowska Agnieszka , Mazur Artur , Brzuszek Marta , Fichna Piotr , Niechciał Elżbieta , Szalecki Mieczysław , Wysocka-Mincewicz Marta , Myśliwiec Małgorzata , Żalińska Magdalena , Szmigierko-Kawko Małgorzata , Noczyńska Anna , Zubkiewicz-Kucharska Agnieszka , Chobot Agata , Górska-Flak Karolina , Ochab Agnieszka , Szadkowska Agnieszka , Wyka Krystyna , Pietrzak Iwona , Pilecki Olgierd , Jarosz-Chobot Przemysława , Rusak Ewa , Beń-Skowronek Iwona , Sieniawska Joanna , Szypowska Agnieszka , Nazim Joanna , Walczak Mieczysław , Jóźwa Anita , Marcinkiewicz Katarzyna , Powell Michael , Amoroso Marie , Rees Smith Bernard , Furmaniak Jadwiga

Background and Aims: A pre-clinical stage of type 1 diabetes (T1D) often precedes by many years the overt clinical symptoms. Diagnosis during this period is often difficult and is based on the presence of specific islet autoantibodies in the subject's blood. First-degree relatives of patients with T1D were tested using the 3 Screen ICA TM ELISA (RSR Ltd) for combined testing for autoantibodies to GAD65 (glutamic acid decarboxylase, 65kDa isoform), ZnT8 (z...