ESPE Abstracts

Introduction: Obesity leads to the development of hypertension, cardiovascular diseases, disorders of carbohydrate metabolism, which are components of the metabolic syndrome. The nature of the changes of lipid homeostasis, leptin and adiponectin levels in relation to the severity of metabolic syndrome are not well understood.Materials and methods: 48 people with the metabolic syndrome (24, 16–18 years old and 24 young adults (19–22 years)) are ...

A seventeen-year-old girl came to outpatient clinic complaining of enlargement and pains in the right eye. She had a history of a mild weight loss, anxiety and blurred vision for the last few weeks. She was referred from another clinic for evaluation of suspected hyperthyroidism. There was no family history of toxic goiter or exophthalmos. Her grandmother had a papillary thyroid cancer. On physical examination, the patient showed a significant increase in size in the right eye...

Introduction: Widespread obesity, as well as dystyroidism, dictates the investigation of possible thyroid dysfunction in young people with metabolic syndrome (MS).Aim: Study of thyroid status in young people with metabolic syndrome.Materials and methods: The study involved 46 patients (25 boys and 21 girls) with MS at the age of 18 ± 3.1 years. The inclusion criteria were an increase in body m...

Background: Schaaf-Yang syndrome is caused by heterozygous mutation in the MAGEL2 gene (605283) on chromosome 15q11. Schaaf-Yang Syndrome is an autosomal dominant multisystem disorder characterized by psychomotor and mental retardation, hypotension, and behavioral abnormalities. Additional signs include joint contractures, feeding difficulties and various dysmorphic features. The severity of the disorder varies greatly: some patients may live with moderate dis...

Aim: To study of the pathology of the upper gastrointestinal tract in obese young people.Materials and Methods: 87 young people with primary obesity (body mass index above 30 kg / m²), 40 boys (45.9%), mean age 17.9 ± 2.2 years (group 1) were under observation. Conducted clinical, laboratory and instrumental examination, esophagogastroduodenoscopy, Ph-metry and determination of H.Pylori infection. The 2nd g...

Introduction: Due to the widespread occurrence of both obesity and hypothyroidism, physicians need to be especially attentive to the possible thyroid dysfunction in obese patients. The relationship between thyroid hormones and obesity in combination with insulin resistance in young people is not fully understood.Materials and Methods: In order to study of thyroid status in young people with overweight and obesity in comb...

Aim: To determine the efficiency of α-lipoic acid in metabolic syndrome treatment in children.Materials and methods: 44 children with metabolic syndrome are observed. The diagnosis of metabolic syndrome is made on the base of obesity, arterial hypertension, disorders of carbohydrate and lipid metabolism according to the ATP III (2001) и IDF (2005) recommendations. All patients are randomized into 2 groups: 22 ch...