hrp0082p3-d2-835 | Growth (1) | ESPE2014

An Unusual Case of a Child with GH Deficiency and Arnold-Chiari Malformation Type I

Xatzipsalti Maria , Polychroni Ioulia , Vazeou Andriani , Stamogiannou Lela

Background: Arnold-Chiari malformations (CM), types I-IV, refer to a spectrum of congenital hindbrain maldevelopments characterized by downward herniation of the cerebellar tonsils. CM-I is defined as tonsillar herniation of 3–5 mm below the foramen magnum and is the most common and the least severe of the spectrum.Objective and hypotheses: Children with CM-I usually are asymptomatic and often diagnosed in adulthood, therefore early presentation of ...

hrp0084p3-1043 | Growth | ESPE2015

GH Deficiency in a Patient with 4p16 Deletion: An Infrequent Association with Wolf–Hirschhorn Syndrome

Polychroni Ioulia , Xatzipsalti Maria , Fryssira Helen , Stamogiannou Lela

Background: Wolf–Hirschhorn syndrome (WHS) is caused by variably-sized deletion of chromosome 4 involving 4p16 whose typical craniofacial features are ‘Greek warrior helmet appearance’ of the nose, microcephaly and prominent grabella. Almost all patients show mental retardation and growth delay.Case presentation: We report on a patient carrying a 4p16 deletion and GH deficiency treated with recombinant human GH (rhGH). The patient is male,...

hrp0089p1-p074 | Diabetes & Insulin P1 | ESPE2018

Catheter Site Selection and Anthropometric Measurements at Subjects with Type 1 Diabetes and Continuous Subcutaneous Insulin Infusion

Xatzipsalti Maria , Vakaki Marina , Mentesidou Lida , Kourti Afroditi , Patouni Konstantina , Choundala Anna , Stamogiannou Lela , Vazeou Andriani

Introduction: The selection of the insulin catheter length for pump T1D users is based mainly on age and though different sites for insertion have been suggested, it is not clear what the ideal site is according to each person’s body type and subcutaneous fat.Aid: Aid of the study is to identify the proper sites for insulin catheter insertion according to subcutaneous fat and anthropometric characteristics.Methods: Study group...

hrp0089p2-p090 | Diabetes & Insulin P2 | ESPE2018

An Unusual Case of an Exclusively Vegan Child with Diabetic Acidosis

Xatzipsalti Maria , Konstantakopoulos Sotiris , Kourti Afroditi , Anastasoudi Maria , Fafoula Olga , Limperatou Christina , Stamogiannou Lela , Vazeou Andriani

Case presentation: A 17 month old female child was transferred to our hospital from another hospital where she was admitted to the intensive care unit (ICU) due to cerebral edema, diabetic acidosis and severe dehydration. The patient had fever, polyuria, polydipsia and vomiting presented four days before admission. At her admission she was unconscious with dilated pupils, no reaction to painful stimuli (GCS 4/15) and Kussmaul breathing. Her initial blood glucose level was 391 ...

hrp0089p3-p209 | GH & IGFs P3 | ESPE2018

Vitamin D Status in Children with Isolated Idiopathic GH Deficiency (GHD) in North and Central Greece

Tsiroukidou Kyriaki , Xatzipsalti Maria , Mameka Iliana , Polychroni Ioulia , Vamvakis Anastasios , Papagianni Maria , Stamogiannou Lela

Background: Vitamin D status in children with isolated GHD has been analyzed in few studies with controversial results. The aim of the study was to assess vitamin D status in children with idiopathic GHD in North and Central Greece.Materials and methods: 128 children (M/F: 76/61, mean age 9.5 (S.D.±3.5 years) with isolated GHD were compared with 65 controls (M/F: 46/3, mean age 9.3 (S.D.±3.2 years). Children were d...

hrp0082p3-d2-827 | Growth (1) | ESPE2014

Impairment of Glucose Metabolism in GH Deficient Children Under GH Replacement

Xatzipsalti Maria , Mitravela Vasiliki-Ioanna , Polichroni Ioulia , Delis Dimitrios , Vazeou Andriani , Stamogiannou Lela

Background: GH replacement therapy in children with GH deficiency (GHD) mainly promotes linear growth. There are few studies fully analyzed the metabolic consequences of GH therapy.Objective and hypotheses: To study the effects of GH replacement therapy on glucose metabolism in patients with GHD.Method: Sixty two children {mean age (S.D. 8.6 (3.3,) years; 35 boys, 10 SGA, 50 prepubertal who were under treatment with ...

hrp0084p3-953 | GH & IGF | ESPE2015

Vitamin D Levels and not Vitamin A are Correlated with Height Velocity in Children with GH Deficiency Who are Under GH Treatment

Xatzipsalti Maria , Polychroni Ioulia , Vazeou Andriani , Maravelia Vasiliki , Papadimitriou Eirini , Stamogiannou Lela

Background: It has been suggested that Vitamin A intake may affect height velocity in children with GH deficiency (GHD) who were under GH replacement (GHR).Objective and hypotheses: Aim of the study was to evaluate vitamin A levels in GHD children under GHR.Method: Vitamin A levels were measured in 38 children (23 males, mean age 10.8 (S.D. 3.3) years) with GHD, after mean duration of GH treatment of 3.1 (S.D....

hrp0082p2-d3-342 | Diabetes (2) | ESPE2014

Prolonged Treatment with Vitamin D Supplementation and High Dose is Necessary to Treat Vitamin D Deficiency/Insufficiency (VDD/I) in Children and Adolescents with Type 1 Diabetes

Xatzipsalti Maria , Dolianiti Maria , Papadopoulou Konstantina , Kouloufakou Penelope , Mitravela Vasiliki-Ioanna , Dracopoulou Maria , Stamogiannou Lela , Vazeou Andriani

Background: Increased frequency of VDD/I has been found in warmer countries over the last years.Objective and hypotheses: To evaluate the response to vitamin D treatment in VDD/I among children and adolescents with type 1 diabetes.Method: Total 25OHvitamin D levels (VDL) were measured in 76 consecutive children and adolescents with type 1 diabetes (36 males, mean age (S.D.) 13.6 (5.09) years, median disease duration ...