hrp0082p2-d2-374 | Fat Metabolism & Obesity (1) | ESPE2014

The Role of Bone and Fat Tissue in Glucose Metabolism in Two Different Metabolic Conditions: Obesity and Diabetes Mellitus Type 1: Pilot Study

Wedrychowicz Anna , Sztefko Krystyna , Starzyk Jerzy

Background: Recent studies have shown a new link between skeleton, fat tissue, and insulin action. However, clinical data are still limited, especially in children.Objective: The aim of the presented study was to investigate the relationship between bone and fat hormones and glucose metabolism in children with type 1 diabetes mellitus (T1DM) and obesity.Methods: Forty-six T1DM children, mean age 12.2±4.6 years, mean BMI 20.0&#...

hrp0084p3-890 | Fat | ESPE2015

Does Vitamin D Influence Energy Metabolism in Children and Adolescents?

Wedrychowicz Anna , Sztefko Krystyna , Starzyk Jerzy

Background: Recent years bring a lot of data of the important role of vitamin D in different physiological processes, including a prevention from pathological states.Objective and hypotheses: The aim of the study was to analyze associations between serum level of vitamin D and some markers of glucose and lipid metabolism but also as well bone-related molecules as adipokines and in children and adolescents.Method: 57 patients, 40 wi...

hrp0082p2-d3-387 | Fat Metabolism & Obesity (2) | ESPE2014

Enhanced Liver Fibrosis Test in Obese Children with Ultrasound-Proven Steatosis

Sztefko Krystyna , Szybowska Patrycja , Wojcik Malgorzata , Starzyk Jerzy B

Background: Non-alcoholic fatty liver disease (NAFLD) in obese children is a diagnostic challenge. Presently recommended markers of liver steatosis and risk of progression to fibrosis are: ultrasound imaging (US) and liver aminotransferases (ALT and AST). Owing to the poor sensitivity of these tests, there is a need to search for biomarkers which could indicate early stages of NAFLD. The enhanced liver fibrosis test (ELF) based on the combination of serum concentration of hyal...

hrp0089p3-p243 | Growth & Syndromes P3 | ESPE2018

Increased Serum Activity of Liver Aminotransferases in Young Patients with Turner Syndrome

Wojcik Malgorzata , Ruszala Anna , Janus Dominika , Sztefko Krystyna , Starzyk Jerzy B.

Background: Liver tests abnormalities are common in adult patients with Turner Syndrome (TS). The data regarding liver tests in children and adolescents with TS remain lacking.Design and patients: A cross-sectional review of liver function of 100 girls with TS (age range 4–16, the mean BMI SDS 0.63 [−1,86 −6,78]); 56 receiving rhGH therapy (9 obese, 47 normal weight), and 44 receiving rhGH therapy and estrogen or estrogen/progesterone ho...

hrp0092p3-288 | Late Breaking Abstracts | ESPE2019

Circulating Chemerin may be Associated with Early Vascular Pathology in Obese Children without Overt Arterial Hypertension – Preliminary Results

Wójcik Małgorzata , Kozioł-Kozakowska Agnieszka , Januś Dominika , Furtak Aleksandra , Małek Agnieszka , Sztefko Krystyna , Starzyk Jerzy

Elevated chemerin level is observed in obese patients with metabolic syndrome and arterial hypertension but it is not known if measurement of this hormone have any prognostic value before the occurrence of clinically overt complications of obesity. The aim of the study was to investigate the relationship between serum chemerin level and 24h blood pressure monitoring (ABPM), and intima media thickness in obese children.Methods: The study ...