hrp0097p1-541 | Pituitary, Neuroendocrinology and Puberty | ESPE2023

Prediction of Adult Height Based on Automated Bone Age Estimation in Early Puberty: A Single-Center Prospective Study

Huseyin Yigit Murat , Yesiltepe Mutlu Gul , Eviz Elif , Hatun Sukru

Introduction: In cases of precocious puberty, an important factor in making treatment decisions is when adult height estimates based on bone age (BA) determination are behind midparental height. In Turkey, clinicians often use the Greulich Pyle (GP) atlas to determine BA, which can lead to significant differences between assessors. The aim of this study was to compare estimated adult height (EAH) calculations based on BA determined by the automated BoneXpert m...

hrp0092p2-240 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Bone Age Determination in Girls with Early Puberty and Limitations of Adult Height Prediction: Can Automated Evaluation (BoneXpert™)be a Solution?

Yesiltepe-Mutlu Gul , Capaci Merve , Uzunkopru Gizem , Hatun Sükrü

Introduction: One of the factors affecting the treatment decision in early puberty is bone age (BA) evaluation and adult height prediction (AHP), accordingly. These calculations have certain limitations. In this study, we aimed to compare the AHP results calculated by Bayley-Pinneau (BP) and Roche-Wainer-Thissen(RWT) methods based on BA evaluation by using Greulich-Pyle(GP) atlas and BoneXpert™ software.Methods: A t...

hrp0089p3-p298 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

Distinct Presentations of McCune Albright Syndrome, Report of Two Cases

Yesiltepe Mutlu Gul , Kabataş Eryilmaz Sema , Ceylaner Serdar , Hatun Sukru

McCune-Albright Syndrome is a rare genetic disorder characterized by triad of polyostotic fibrous dysplasia of bone, precocious puberty and café au lait skin pigmentation. It is resulted from an activating mutation in the GNAS gene encoding the alpha subunitof stimulatory G protein. Here we present two cases with McCune Albright syndrome presenting with different clinical findings.Case 1: A 7-year and 6 month-old girl presented with breast ...

hrp0086p1-p223 | Diabetes P1 | ESPE2016

The Relationship between the Serum Irisin Levels and the Metabolic Control in adolescents with Type 1 Diabetes

Yuksel Aysegul , Seymen Karabulut Gulcan , Baydemir Canan , Yesiltepe Mutlu Gul , Isgoren Serkan , Cekmen Mustafa , Hatun Sukru

Background: Irisin is an adipomyokine secreted by many tissues. Because it has known relationships with the energy metabolism and exercise, its relationships with obesity and type 2 diabetes (T2D) are being focused on. Its relationship with type 1 diabetes (T1D) is unknown.Objective and hypotheses: In this study, the relationships between the serum irisin level and the metabolic control were investigated in adolescents with T1D.Met...

hrp0097fc5.3 | Diabetes and insulin 1 | ESPE2023

How feasible is it to meet the Time in Tight Range (TITR) target with Automatic Insulin Delivery (AID)?: 2128-day real-world data from a single center

Eviz Elif , Ecem Killi Nesrin , Ege Karakus Kagan , Can Ecem , Gokce Tugba , Yesiltepe Mutlu Gul , Hatun Sukru

Introduction: With the development and use of automated insulin delivery (AID) technologies like Advanced Hybrid Closed Loop (AHCL or Minimed 780G) system, it becomes possible to achieve tighter glycemic control. A new parameter called “Time in Tight Range” (TITR, 70-140 mg/dL) has been proposed to evaluate glycemic control in the latest consensus on the use of continuous glucose monitoring (CGM) data in diabetes research. This study aims to assess...