hrp0082p3-d1-882 | Perinatal and Neonatal Endocrinology | ESPE2014

Project Episga: PreMeb Presentation, Subject Recruitment, and Initial Data

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , Hoyo-Moracho Marta , Lorente-Blazquez Isabel , Lorente Raquel Gomez de Segura , Campos Dorleta Perez , Rodriguez-Rivera Victor Manuel , Macarulla-Arenaza Maria Teresa

Background: Up to 50% SGA did not do a proper catch up (for over/under) and may have implications in size, metabolic, cardiovascular. Arises: epiSGA – PreMeb Project. Global approach to study.Objective: Create clinical cohort of SGA for monitoring, assessment catch-up, use GHRH requirements, environmental/social factors and variables influence on clinical, laboratory and metabolic profiles in order to progress in the knowledge of natural history. Pr...

hrp0082p3-d2-889 | Perinatal and Neonatal Endocrinology (1) | ESPE2014

Evolution and Epidemiological Assessment of the Influence of Sociological Variables of Children Born SGA in the Last Decade in Basque Country

Diez-Lopez Ignacio , Hoyo-Moracho Marta , Sarasua-Miranda Ainhoa , Lorente-Blazquez Isabel , Rodriguez-Rivera Victor Manuel , Macarulla-Arenaza Maria Teresa , de Segura Lorente Raquel Gomez , Campos Dorleta Perez

Background: Although the theoretical impact of small in weight and/or size at birth (<2 SDS for EG) is 3–5% (3.5% in the Basque Country (source: Local Government) the socio-economic situation in our country has conditioned a change in its l although 50% at 2 years did not do a proper catch up (by excess or defect) with potential impact on future size and metabolic complications, cardiovascular require specific monitoring.Objective: To assess soc...

hrp0084p3-929 | GH &amp; IGF | ESPE2015

Biochemical Profiles Differentials by SGA Children Catch Up

Diez-Lopez Ignacio , Sarasua-Miranda Ainhoa , del Hoyo-Moracho Marta , de Segura Raquel Gomez , Perez-Campos Dorleta , Mararulla-Arenaza Maria Teresa , Rodriguez-Rivera Victor Manuel

Background: SGA cohort study in analytical and metabolic variables at 3 and 12 months of age with somatométrica situation.Material and methods: Live births in singleton pregnancies in our hospital during 2012–2014, PEG were studied according EG and weight/height (Spanish Tablas 2008). Tours are conducted at 0, 3, 6, 9, 12 months, with measurements of weight, height and perimeter. Blood samples are obtained at least fasting discussed 4h and exce...

hrp0084p3-1094 | Perinatal | ESPE2015

EPIPEG-PREMEB Proyect. Clinical Situation before 12 months go on a SGA Population

Sarasua-Miranda Ainhoa , Diez-Lopez Ignacio , del Hoyo-Moracho Marta , Lorente-Blazquez Isabel , de Segura Raquel Gomez , Perez-Campos Dorleta , Macarulla-Arenaza Maria Teresa , Rodriguez-Rivera Victor Manuel

Background: Cohort SGA in North of Spain – EPIPEG.Objective and hypotheses: Establish a SGA cohort for monitoring, assessment catch-up, and analysis of middle-environmental and social factors.Method: We study live births in singleton pregnancies in our hospital during 2012–2014, and are classified according age gestation (EG) and weight/height (Spanish growth 2008). Visits were made at 0, 3, 6, 9, 12 months, with measurem...

hrp0084p3-1095 | Perinatal | ESPE2015

McCune–Allbright Syndrome in a Male Newborn with Hyperthiroydism

Valencia Maria Esperanza Rueda , Rodriguez Olga Perez , de Lara Diego Lopez , Sosa Esther Vaquero , Maresca Maria Isabel Armada , Vega Enrique Criado

Introduction: McCune–Albright syndrome (MAS) is a rare disease defined by café-au-lait spots, gonadotropin-precocious puberty and fibrous dysplasia. It could be associated with others endocrinopathies: thyroid involvement as a common feature. The prevalence is very low, being outstanding the neonatal diagnosis, especially in males.Case presentation: A male term newborn with a café-au-lait extensive spot involving the back, arms, legs and s...

hrp0094p2-396 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2021

Combining big data science with clinics: Novel approach for understanding human sex development and its variants.

Rodriguez Gutierrez Daniel , Sproll Patrick , Von der Decken Isabel , Stevenson Brian , Lang-Muritano Mariarosaria , Konrad Daniel , L’Allemand Dagmar , Nef Serge , Biason-Lauber Anna ,

Background/Introduction: Whole exome sequencing (WES) revolutionized clinical genetics in patients with differences of sex development (DSD). However, our ability to interpret WES data is limited by our incomplete understanding of the mechanisms involved in DSD. Thus, we created a methodology that scores potential candidates based on single cells transcriptomics of human male gonadal cells and applied it to WES data from a cohort of genetically male (46,XY) DS...

hrp0097p1-264 | Fat, Metabolism and Obesity | ESPE2023

Implementation of the EOSS-P Risk Scale in children and adolescents living with obesity

Gonzalez Diego , Rodriguez Roberto , Garibay-Nieto Nayely , Villanueva-Ortega Eréndira , Aguilar-Cuarto Karina , Pedraza Karen , Fuentes Zendy , Ruiz Alejandra , María Hernandez Ana , Prado Edith , Ruiz Arturo

Body Mass Index (BMI) has a high association with body fat percentage and direct association with a higher degree of comorbidities. Categorizing patients only by the degree of obesity, as has been done over time, restricts the possibility of detecting and giving timely treatment to other aspects. The Edmonton Obesity Staging System for Pediatrics (EOSS-P) has been proposed as a tool to categorize obesity not only by BMI, but also by assessing metabolic complications, functiona...

hrp0098p1-47 | Fat, Metabolism and Obesity 1 | ESPE2024

Sleep quality and telomere length after long-term impact of a lifestyle intervention in patients with abdominal obesity

Cristina Azcona-Sanjulian Maria , Catalan Lamban Ana , Ojeda-Rodriguez Ana , Jesus Chueca Guindulain Maria , Berrade Zubiri Sara , Marti del Moral Amelia

Aim: to assess telomere length (TL) changes and sleep quality in patients with abdominal obesity after a lifestyle intervention.Patients, Material and Methods: 122 patients with abdominal obesity, aged 7-16 years, were included in a control randomized intervention study (NCT031472). Abdominal obesity was diagnosed using the waist circumference. The intervention included a 2-month intensive phase and follow-up at 12 and 2...

hrp0092p1-213 | GH and IGFs (1) | ESPE2019

Determinants of Final Height in Patients Born Small for Gestational Age Treated with Recombinant Growth Hormone

Adler Elodie , Lambert Anne-sophie , Bouvattier Claire , Teinturier Cécile , Bougnères Pierre , Rodrigue Danielle , Rothbuhler Anya , De Boissieu Paul , Linglart Agnès

Introduction: About 15% of children born small for gestational age (SGA) do not reach final height within normal range. Recombinant human growth Hormone (rhGH) has shown to be effective in catching up growth velocity and height in children born SGA.The objective of our study is to identify the predictive factors of final height in children born SGA treated with rhGH.Materials and Methods: Monocentric, retrospective s...

hrp0094p2-139 | Diabetes and insulin | ESPE2021

Different schemes of insulin therapy (CSII and MDII) in children with DM1 in a Dnipro city.

Yenhovatova Viktoria , Zelinska Nataliya , Globa Evgenia ,

Background: Due to the Ukrainian Pediatric Diabetes Register (UPDR) the number of children with DM1 0-17 y.o. in 2019 was 9860 (1 in 769), with Dm2 36 (1 in 210,547) with neonatal DM (NDM) 66 (1 in 115,000), with MODY 40 cases (1 in 114,844). The diabetes prevalence rates increased from 9.3 (per 1000) in 2007 up to 12,57 (per 1000) in 2018. CSII is well established in pediatric patients with DM1. Most studies focus on such parameters as HbA1c levels...