hrp0094p2-173 | Fat, metabolism and obesity | ESPE2021

Evaluation of the BigO system during the COVID-19 outbreak in Greece

Kassari Penio , Tragomalou Athanasia , Vourdoumpa Aikaterini , Koutaki Diamanto , Papadopoulou Marina , Manou Maria , Ioakeimidis Ioannis , Filis Konstantinos , Theodoropoulou Eleni , Lymperopoulos Giorgos , Ferri Daniel , Karavidopoulou Youla , Stefanopoulos Leandros , Diou Christos , Lekka Eirini , Maglaveras Nicos , Delopoulos Anastasios , Charmandari Evangelia ,

Background: Since December 2019, the world has witnessed a global pandemic due to SARS-CoV-2 coronavirus (COVID-19), which has led to lifestyle changes as a result of Public Health Regulations and Guidelines introduced by governments worldwide.Objective: To determine the body mass index (BMI) trajectory in children and adolescents with overweight and obesity with respect to the COVID-19 outbreak in Greece.<p class="a...

hrp0094p2-183 | Fat, metabolism and obesity | ESPE2021

Evaluation of the BigO system in a clinical setting in Greece

Kassari Penio , Tragomalou Athanasia , Vourdoumpa Aikaterini , Koutaki Diamanto , Papadopoulou Marina , Manou Maria , Ioakeimidis Ioannis , Filis Konstantinos , Theodoropoulou Eleni , Lymperopoulos Giorgos , Ferri Daniel , Karavidopoulou Youla , Stefanopoulos Leandros , Diou Christos , Lekka Eirini , Maglaveras Nicos , Delopoulos Anastasios , Charmandari Evangelia ,

Background: Obesity in childhood and adolescence represents one of the most important public health problems. Over the last decade, the widespread use of personal digital technologies, such as smart mobiles and accelerometers, create new possibilities for collecting bevavioral data objectively.Objective: To evaluate the body mass index (BMI) trajectory after at least one month’s use of the BigO system.<p class="...

hrp0097p2-43 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Persistent Müllerian duct syndrome and the identification of a yet unreported homozygous mutation in AMHR2 gene

Cima Luminita-Nicoleta , Oprescu Raluca , Zubaci Ana , Tarna Mihaela , Iliescu Marina , Dumitrache Sabina , Grosu Iustina , Draghici Isabela , Chirita-Emandi Adela , Puiu Maria , Gabriela Barbu Carmen , Viorica Popescu Mihaela , Fica Simona

Introduction: Persistent Müllerian duct syndrome (PMDS) is a rare disorder of sex development (DSD) characterized by the persistence of Müllerian derivatives, the uterus and/or fallopian tubes, in otherwise normally virilized boys. PMDS is caused by mutations in the genes coding anti-Müllerian hormone (AMH, PMDS type 1) or the AMH receptor (AMHR2 gene, PMDS type 2) and it usually presents as undescended testes (cryptorchidism) or inguinal hernia...

hrp0082p1-d1-198 | Reproduction | ESPE2014

Stability Conditions in Estradiol Matrix Patches; in vitro Studies for Application in Pediatrics

Ankarberg-Lindgren Carina , Sas Theo

Background: We have previously shown that estradiol (E2) matrix patches for adults could be cut in smaller pieces to administer low doses for pubertal induction in girls with hypogonadism. With a slow increase of the patch size during a few years, serum E2 levels in normal girls undergoing puberty can be closely mimicked.Objective and hypotheses: To evaluate storage conditions once the patch has been cut.Metho...

hrp0084wg6.5 | Turner Syndrome | ESPE2015

Report on the Progress and Difficulties on Transdermal Estradiol Supplementation in Europe

Sas Theo , Ankarberg-Lindgren Carina

Background: The Turner syndrome (TS) Working Group of the ESPE intends to start an international study comparing transdermal estradiol (E2) vs oral E2 in Europe in girls with TS. For this, stable and reliable products for children are needed, for use in different countries with different climates. It has previously been shown that E2 matrix patches for adults can be cut in smaller pieces to administer low doses for pubertal induction in girls. The Turner Working Group plan to ...

hrp0095p1-417 | Adrenals and HPA Axis | ESPE2022

A patient with autoimmune polyglandular syndrome type 1 with atypical presentation

Bazdarska Yuliya , Yordanova Nikolinka , Hristozova Hristina , Krumova Darina , Iotova Violeta

Background: Autoimmune polyglandular syndrome type 1 (APS-1) is &acy; rare multisystem disorder due to mutations in the autoimmune regulator gene (AIRE). APS-1 usually is characterized by a triad of hypoparathyroidism, primary adrenal insufficiency (PAI) and chronic mucocutaneous candidiasis. In the absence of the classic triad, the diagnosis becomes obscure and is often delayed.Case presentation: We report a 12 years ol...

hrp0097p2-231 | Growth and Syndromes | ESPE2023

Growth hormone treatment of short SGA children – experience of tertiary clinic in Bulgaria

Krumova Darina , Zlateva Tanya , Georgieva Ralitsa , Deyanova Yana , Iotova Violeta

Introduction: Fenton (2013) defined small for gestational age children (SGA) as born with birth length and/or weight < 10th percentile for the corresponding gestational age, and clinicians use it ever since. According to the literature, 1 of 10 children born SGA does not catch-up in growth. Wit (2021) suggested to address them as short SGA children. Recombinant human growth hormone (rhGH) treatment in those children have been approved by the FDA in 2001 and...

hrp0098p3-154 | Growth and Syndromes | ESPE2024

An unusual association of Beckwith-Wiedemann syndrome with congenital hypothyreosis, cutaneous haemangiomas and diaphragmatic eventration

Ramosaj Morina Atifete , Krasniqi Elida , Keka Sylaj Alije , Baloku Zejnullahu Arbana

Beckwith-Wiedemann syndrome is a congenital imprinting condition with a heterogenous clinical presentation of overgrowth and an increased childhood cancer risk. Hemangiomas are a rare presentation, while association with diaphragmatic eventration and congenital hypothyroidism was reported even more rarely. This case highlights the presence of some rare anomalies which may be associated with BWS.Case presentation: Personal and disease his...

hrp0092p3-121 | Fat, Metabolism and Obesity | ESPE2019

Associations Between Lipid Parameters and Insulin Resistance in Obese Adolescents

Chaychenko Tetyana , Kharkova Mariia , Rybka Olena

Background: Non-communicable disease epidemic is directly related to the dislipidemia and insulin resistance (IR) that associated with acute cardiovascular events. Meanwhile, there is not much has known about interrelation between this parameters in pediatric patients.Purpose: of the study is to analyze associations between lipids and insulin resistance so as to screen high risk subjects during adolescence.<p class="...

hrp0089p3-p315 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

The Change in Growth’s Velocity in Patients with Premature Puberty Receiving Treatment with Analogues of Lyuliberin

Berseneva Olga , Bashnina Elena , Turkunova Mariia

Background: Suppression of hypothalamic-pituitary-gonadal system activity by luliberin analogues in premature sexual development of the central genesis is accompanied by a decrease in growth’s velocity, sexual development and progression of bone age.Aim: Study of the effectiveness of gonadotropin-releasing hormone agonist therapy, their influence on the physical developmentMethods: 66 patients were treated by triptorelin. Idio...