hrp0089p3-p291 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

Neonatal Panhypopituitarism with Hypoglycemia, Edema, Inspiratory Stridor and Cholestasis

Momm Benita , Nitsch Alexander , Hammer Elke

We report the case of a female newborn, first child of healthy, non-consanguineous parents, born at 42+0 weeks of gestation, who was admitted 21 h after birth with severe hypoglycemia, hypothermia, decreased muscle tone, inspiratory stridor and edema. The course included poor feeding and failure to thrive, hyperbilirubinemia and cholestasis. Infectious or metabolic diseases were ruled out by clinical and laboratory investigations. Hormonal evaluation confirmed the diagnosis of...

hrp0086p2-p523 | Fat Metabolism and Obesity P2 | ESPE2016

Body Image Perception Changes in Obese and Lean Children

Viazava Liudmila , Solntsava Anzhalika , Sukalo Alexander

Background: Body image (BI) is subjective picture of one’s own physical appearance established both by self-observation and by noting the reactions of others. Different BI scales used for screening of the Binge Eating symptoms that strongly linked to obesity.Objective and hypotheses: We supposed to get differences in the own body image perception in overweight and lean children.Method: BI questionnaire (BIQ) and own body satis...

hrp0092p2-109 | Fat, Metabolism and Obesity | ESPE2019

Metabolic Syndrome in Children and Adolescents who Survived After Childhood Cancer

Zhukovskaya Elena , Gavrilova Anna , Nasedkina Tatiana , Chechelnitskaya Serafima , Lisitsa Tatiana , Karelin Alexander , Kasatkin Vladimir , Rumyantsev Alexander

Background/Objectives: During treatment of children and adolescents with cancer, an imbalance of carbohydrate and mineral metabolism may occur, leading to clinical manifestations of the components of the metabolic syndrome. The aim of the work was to study the frequency and severity of various clinical signs associated with metabolic syndrome in a cohort of patients from the Russian Field Clinical Rehabilitation Center.Design/Met...

hrp0086p1-p622 | Growth P1 | ESPE2016

Major Plasma Carotenoids Levels in Growth Hormone Deficient Children

Pankratova Maria , Yusipovich Alexander , Vorontsova Maria , Baizhumanov Adil , Cherkashin Alexander , Shiryaeva Tatiana , Solovchenko Alexei , Peterkova Valentina

Background: Carotenoids are potent antioxidants that affect many different metabolic processes. In plasma, carotenoids are transported with lipoproteins. Growth hormone deficiency (GHD) is known to induce oxidative stress and deterioration in the lipid profile, which can change the level and composition of carotenoids. Particularly interesting to measure these parameters in GHD children.Objective and hypotheses: The aim of this study is to examine the am...

hrp0092p1-121 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology | ESPE2019

Lower Urinary Tract Dysfunction and Infection in Girls with Disorders of Sex Development and Urogenital Sinus

Anikiev Alexander , Brovin Dmitriy , Volodko Elena , Okulov Alexey , Andreeva Elena

Introduction: Two-stage surgical feminization is a part of the multidisciplinary rehabilitation of girls with external genital virilization. The first stage involves clitoroplasty and labioplasty with preservation of urogenital sinus (US) in girls with third degree of virilization according to Prader classification and higher. US eliminating is performed by second stage in the puberty. Persistence US may cause dysfunction of urodynamics and infections of the l...

hrp0092p1-393 | Growth and Syndromes (to include Turner Syndrome) (2) | ESPE2019

Evaluation of Body Composition and Resting Metabolic Rate in Children with Growth Hormone Deficiency

Masueva Madina , Okorokov Pavel , Pankratova Maria , Yusipovich Alexander , Shiryaeva Tatiana

Background/Aims: It is known that growth hormone regulated metabolic processes, including lipid metabolism and the amount of adipose tissue. The purpose was to study metabolic rates at rest in children with growth hormone deficiency (GHD) and their relationship with lipid and hormone levels.Objective: To analyse the body composition and resting metabolic rate (RMR) among prepubertal children with GHD<p class="abstext...

hrp0089rfc5.4 | Thyroid | ESPE2018

The Value of Cytological, Histological and US Examination to Determine of Management Children with Nodular Goiter

Brovin Dmitriy , Peterkova Valentina , Anikiev Alexander , Danilenko Oleg , Kuznetsov Nikolay

Introduction: To date, there are no clear indications for surgical treatment of nodular goiter in children. Current scheme of diagnostic evaluation thyroid nodules in children is not always justified. A number of patients either go to the removal of thyroid remnants when a carcinoma is found in the histological examination and the need for radioiodine therapy, or are at risk of surgery if the results of the final histology show that the disease is benign.<p class="abstext"...

hrp0089p3-p074 | Diabetes &amp; Insulin P3 | ESPE2018

Association between Prior Toxic Stressors and Development of T2DM in Adolescents

Adamidis Adam , Knee Alexander , Cobb Victoria , Conroy Rushika

Background: Low stress resilience in late adolescence and psychosocial traumatic events in adulthood have been linked to a higher risk of developing type 2 diabetes (T2DM) later on in life. However, limited data is available regarding whether prior stressors are related to the risk of developing T2DM in adolescence.Objective: We sought to determine the potential association between prior toxic stressors and T2DM in adolescence.Desi...

hrp0089p3-p207 | GH &amp; IGFs P3 | ESPE2018

Erythropoietin and Granulocyte Macrophage Colony Stimulating Factor Levels in Growth Hormone Deficient Children after 1 Year of Growth Hormone Therapy

Pankratova Maria , Vorontsova Maria , Yusipovich Alexander , Shiryaeva Tatiana , Peterkova Valentina

Background/Aims: An increase in growth rate in children suffering from growth hormone deficiency (GHD) subjected to recombinant growth hormone treatment (rGHT) was shown to be accompanied by acceleration of metabolic processes that may stimulate hematopoiesis. Therefore, the aim of the present study was to examine the effects of one year rGHT on erythropoietin (EPO) and Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) levels in GHD children.Meth...

hrp0089p3-p322 | Sex Differentiation, Gonads and Gynaecology or Sex Endocrinology P3 | ESPE2018

New Method of Surgical Correction of Female Hypospadias in Girls with Disorders of Sex Development and Stenosis of Artificial Introitus

Anikief Alexander , Brovin Dmitriy , Volodko Elena , Okulov Alexey

Introduction: Female hypospadias (FH) is one of disorders of sex development signs (DSD). Short and wide urethra that opens into the vagina predisposes to occurrence of recurrent infection of urinary tract, vaginal voiding and postoperative narrowing of artificial vaginal introitus (AVI).Aim: Improve the results of correction FH with stenosis AVI using reintroitoplasty separating the urinary and genital tracts in patients with DSD....